Catalog No.
YHJ15301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser36-Ser202
Predicted molecular weight
21.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86TI2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dipeptidyl peptidase 9, Dipeptidyl peptidase IX, DPRP-2, DPLP9, Dipeptidyl peptidase IV-related protein 2, DPP IX, DPP9, Dipeptidyl peptidase-like protein 9, DP9, DPRP2
Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase-1- and Gasdermin-Dependent Cell Death., PMID:40498275
A fluorescent sensor for real-time monitoring of DPP8/9 reveals crucial roles in immunity and cancer., PMID:40355159
DPP8/9 processing of human AK2 unmasks an IAP binding motif., PMID:40312560
The multifunctional regulatory post-proline protease dipeptidyl peptidase 9 and its inhibitors: new opportunities for therapeutics., PMID:40293537
Multimodal cell maps as a foundation for structural and functional genomics., PMID:40205054
Dipeptidyl peptidase 9 (DPP9) depletion from hepatocytes in experimental primary liver cancer., PMID:40187163
Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors., PMID:40180908
Diverse autoinhibitory mechanisms of FIIND-containing proteins: Insight into regulation of NLRP1 and CARD8 inflammasome., PMID:39854601
Role of IPF genetic risk loci in post-COVID-19 lung abnormalities: a cohort study., PMID:39832890
Pinocembrin activation of DPP9 inhibits NLRP1 inflammasome activation to alleviate cerebral ischemia/reperfusion-induced lung and intestinal injury., PMID:39676095
Molecular Targeted Engagement of DPP9 in Rat Tissue Using CETSA, SP3 Processing, and Absolute Quantitation Mass Spectrometry., PMID:39642389
The serine protease DPP9 and the redox sensor KEAP1 form a mutually inhibitory complex., PMID:39615677
In Silico analysis unveils rs2109069 of DPP9 as a potential catalyst for COVID-19 severity and risk of inflammatory symptoms., PMID:39615159
An Interdisciplinary Approach Provides Insights into the Pronounced Selectivity of Compound 42 for DPP9., PMID:39552560
Hippocampal dipeptidyl peptidase 9 bidirectionally regulates memory associated with synaptic plasticity., PMID:39369958
Cosolvent Molecular Dynamics Applied to DPP4, DPP8 and DPP9: Reproduction of Important Binding Features and Use in Inhibitor Design., PMID:39332821
Discovery of the selective and nanomolar inhibitor of DPP-4 more potent than sitagliptin by structure-guided rational design., PMID:39265251
DPP9 regulates NQO1 and ROS to promote resistance to chemotherapy in liver cancer cells., PMID:39094401
Vaccinia virus F1L blocks the ribotoxic stress response to subvert ZAKα-dependent NLRP1 inflammasome activation., PMID:39086059
Dipeptidyl peptidases and E3 ligases of N-degron pathways cooperate to regulate protein stability., PMID:38874443
Single nucleotide variants in the CCL2, OAS1 and DPP9 genes and their association with the severity of COVID-19 in an Ecuadorian population., PMID:38694517
Study on the correlation between DPP9 rs2109069 and IFNAR2 rs2236757 polymorphisms with COVID-19 mortality., PMID:38660988
A combination of virtual screening, molecular dynamics simulation, MM/PBSA, ADMET, and DFT calculations to identify a potential DPP4 inhibitor., PMID:38565703
Dipeptidyl-peptidase 9 regulates the dynamics of tumorigenesis and metastasis in breast cancer., PMID:38531482
N-terminal processing by dipeptidyl peptidase 9: Cut and Go!, PMID:38461970
DPP8/9 inhibition attenuates the TGF-β1-induced excessive deposition of extracellular matrix (ECM) in human mesangial cells via Smad and Akt signaling pathways., PMID:38458339
Development of the dipeptidyl peptidase 4 family and its association with lung diseases: a narrative review., PMID:38249892
Exploring immunoregulatory properties of a phenolic-enriched maple syrup extract through integrated proteomics and in vitro assays., PMID:38019191
DPP8/9 are not Required to Cleave Most Proline-Containing Peptides., PMID:37982048
Mapping the genetic architecture of idiopathic pulmonary fibrosis: Meta-analysis and epidemiological evidence of case-control studies., PMID:37977320
CASP1 is a target for combination therapy in pancreatic cancer., PMID:37949157
Alternative splicing in lung influences COVID-19 severity and respiratory diseases., PMID:37794074
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers., PMID:37742993
DPP9 Comes of Age: Highly Selective Inhibitors Promise New Therapeutic Opportunities., PMID:37721863
Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin., PMID:37721854
DPP9 Stabilizes NRF2 to Suppress Ferroptosis and Induce Sorafenib Resistance in Clear Cell Renal Cell Carcinoma., PMID:37713596
Hemophagocytic lymphohistiocytosis-like hyperinflammation due to a de novo mutation in DPP9., PMID:37544411
Licochalcone A Derivatives as Selective Dipeptidyl Peptidase 4 Inhibitors with Anti-Inflammatory Effects., PMID:37337963
Activation of the NLRP1 Inflammasome and Its Role in Transmissible Gastroenteritis Coronavirus Infection., PMID:37255428
The amino-dipeptidyl peptidases DPP8 and DPP9: Purification and enzymatic assays., PMID:37230592
CARD8 Inflammasome Activation by HIV-1 Protease., PMID:37074642
DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies., PMID:37048172
SARS-CoV-2 infection in children: A 24 months experience with focus on risk factors in a pediatric tertiary care hospital in Milan, Italy., PMID:36873632
Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19., PMID:36672770
Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation., PMID:36649711
A common variant close to the "tripwire" linker region of NLRP1 contributes to severe COVID-19., PMID:36416944
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection., PMID:36315050
Inflammasome sensor NLRP1 disease variant M1184V promotes autoproteolysis and DPP9 complex formation by stabilizing the FIIND domain., PMID:36309085
Host Genetic Risk Factors Associated with COVID-19 Susceptibility and Severity in Vietnamese., PMID:36292769
Genome-wide association studies of COVID-19: Connecting the dots., PMID:36280088
For research use only. Not for human or drug use.
