Catalog No.
YHJ15201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro945-Leu1320
Predicted molecular weight
44.29 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q86TC9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYPN, Myopalladin, 145 kDa sarcomeric protein, MYOP
The Proteomic Landscape of the Coronary Accessible Heart Cell Surfaceome., PMID:39790063
Phenotype-Genotype Correlation of a Cohort of Patients with Congenital Myopathy: A Single Centre Experience from India., PMID:38968056
Associations of MYPN, TTN, SCN5A, MYO6 and ELN Mutations With Arrhythmias and Subsequent Sudden Cardiac Death: A Case Report of an Ecuadorian Individual., PMID:37936622
Structural and signaling proteins in the Z-disk and their role in cardiomyopathies., PMID:36935760
Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities., PMID:36927816
Outcomes of a multicenter study of the causes of sudden cardiac death (SCD) in the Czech Republic and primary prevention of cardiac arrest in relatives., PMID:35882527
Restrictive cardiomyopathy: from genetics and clinical overview to animal modeling., PMID:35345275
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart., PMID:34647998
Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload., PMID:34558411
Transcriptome profiling analysis of muscle tissue reveals potential candidate genes affecting water holding capacity in Chinese Simmental beef cattle., PMID:34099805
Shotgun proteomics for the preliminary identification of biomarkers of beef sensory tenderness, juiciness and chewiness from plasma and muscle of young Limousin-sired bulls., PMID:33714802
Genetic Spectrum of Left Ventricular Non-Compaction in Paediatric Patients., PMID:33049752
SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways., PMID:33048956
[Seroprevalence of anti-Mycoplasma pneumoniae antibodies in otherwise healthy children]., PMID:32730514
Myopalladin promotes muscle growth through modulation of the serum response factor pathway., PMID:31647200
Double missense mutations in cardiac myosin-binding protein C and myopalladin genes: A case report with diffuse coronary disease, complete atrioventricular block, and progression to dilated cardiomyopathy., PMID:31524317
Congenital myopathy with hanging big toe due to homozygous myopalladin (MYPN) mutation., PMID:31133047
A case report of recessive restrictive cardiomyopathy caused by a novel mutation in cardiac troponin I (TNNI3)., PMID:30953456
Zebrafish VCAP1X2 regulates cardiac contractility and proliferation of cardiomyocytes and epicardial cells., PMID:29777134
[Gene mutation and clinical phenotype analysis of patients with Noonan syndrome and hypertrophic cardiomyopathy]., PMID:29050118
Dissection of Z-disc myopalladin gene network involved in the development of restrictive cardiomyopathy using system genetics approach., PMID:28515850
Novel trigenic CACNA1C/DES/MYPN mutations in a family of hypertrophic cardiomyopathy with early repolarization and short QT syndrome., PMID:28427417
Recessive MYPN mutations cause cap myopathy with occasional nemaline rods., PMID:28220527
Two novel candidate genes identified in adults from the Newfoundland population with addictive tendencies towards food., PMID:28115213
Association study between single nucleotide polymorphisms in porcine genes and pork quality traits for fresh consumption and processing into Italian dry-cured ham., PMID:28064046
Biallelic Mutations in MYPN, Encoding Myopalladin, Are Associated with Childhood-Onset, Slowly Progressive Nemaline Myopathy., PMID:28017374
Paving the way for novel treatment strategies in genetic cardiomyopathies., PMID:25541131
Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy., PMID:25541130
Nonsense mutations in BAG3 are associated with early-onset dilated cardiomyopathy in French Canadians., PMID:25448463
SNPs of MYPN and TTN genes are associated to meat and carcass traits in Italian Large White and Italian Duroc pigs., PMID:24158610
Novel mutations in the sarcomeric protein myopalladin in patients with dilated cardiomyopathy., PMID:22892539
Molecular basis for clinical heterogeneity in inherited cardiomyopathies due to myopalladin mutations., PMID:22286171
A novel polymorphism of the MYPN gene and its association with meat quality traits in Bos taurus., PMID:20812196
Analysis of the Z-disc genes PDLIM3 and MYPN in patients with hypertrophic cardiomyopathy., PMID:20801532
Cytoplasmic Ig-domain proteins: cytoskeletal regulators with a role in human disease., PMID:19466753
Mutations in the Z-band protein myopalladin gene and idiopathic dilated cardiomyopathy., PMID:18006477
The palladin/myotilin/myopalladin family of actin-associated scaffolds., PMID:16164966
Mapping, identification of polymorphisms and analysis of allele frequencies in the porcine skeletal muscle myopalladin and titin genes., PMID:14970695
Interaction of nebulin SH3 domain with titin PEVK and myopalladin: implications for the signaling and assembly role of titin and nebulin., PMID:12482578
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies., PMID:11309420
For research use only. Not for human or drug use.
