Catalog No.
YHJ14001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr322-Arg450
Predicted molecular weight
16.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7Z4P5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Growth/differentiation factor 7, GDF-7, GDF7
Growth differentiation factor 7 alleviates the proliferation and metastasis of hepatocellular carcinoma., PMID:39958922
Therapeutic potential and mechanisms of umbilical cord mesenchymal stem cells differentiating into tendon cells and promotion of rotator cuff tendon-bone healing., PMID:39882545
Transcriptional profiling of the M. complexus in naked neck chickens suggest a direct pleiotropic effect of GDF7 on feathering and reduced hatchability., PMID:39548399
Growth differentiation factor 7 pretreatment enhances the therapeutic capacity of bone marrow-derived mesenchymal stromal cells against cerebral ischemia-reperfusion injury., PMID:37879595
Growth differentiation factor 7 autocrine signaling promotes hepatic progenitor cell expansion in liver fibrosis., PMID:37798809
Ligand-specific regulation of transforming growth factor beta superfamily factors by leucine-rich repeats and immunoglobulin-like domains proteins., PMID:37603563
FAM20A mutations and transcriptome analyses of dental pulp tissues of enamel renal syndrome., PMID:37159186
Characterization of Histone Modifications in Late-Stage Rotator Cuff Tendinopathy., PMID:36833423
Growth Differentiation Factor 7 Prevents Sepsis-Induced Acute Lung Injury in Mice., PMID:36588594
Growth Differentiation Factor 7 promotes multiple-lineage differentiation in tenogenic cultures of mesenchymal stem cells., PMID:36261312
Immunogenomic Characteristics of Cell-Death-Associated Genes with Prognostic Implications in Bladder Cancer., PMID:35898507
The combination of BMP12 and KY02111 enhances tendon differentiation in bone marrow-derived equine mesenchymal stromal cells (BM-eMSCs)., PMID:35847484
An Integrated Perspective of Evolution and Development: From Genes to Function to Ear, Lateral Line and Electroreception., PMID:35505776
Secretome screening reveals immunomodulating functions of IFNα-7, PAP and GDF-7 on regulatory T-cells., PMID:34408239
CREB signaling activity correlates with differentiation and survival in medulloblastoma., PMID:34373489
Proliferation and tenogenic differentiation of bone marrow mesenchymal stem cells in a porous collagen sponge scaffold., PMID:33584983
The miR-204-5p/FOXC1/GDF7 axis regulates the osteogenic differentiation of human adipose-derived stem cells via the AKT and p38 signalling pathways., PMID:33461605
The genetic basis and robustness of naked neck mutation in chicken., PMID:33415443
iTRAQ-based proteomic analysis of the molecular mechanisms and downstream effects of fatty acid synthase in osteosarcoma cells., PMID:33405298
TET-dependent GDF7 hypomethylation impairs aqueous humor outflow and serves as a potential therapeutic target in glaucoma., PMID:33388417
A Deletion in GDF7 is Associated with a Heritable Forebrain Commissural Malformation Concurrent with Ventriculomegaly and Interhemispheric Cysts in Cats., PMID:32575532
Concurrent multi-lineage differentiation of mesenchymal stem cells through spatial presentation of growth factors., PMID:32526725
Tenocyte-imprinted substrate: a topography-based inducer for tenogenic differentiation in adipose tissue-derived mesenchymal stem cells., PMID:31896091
Repair of Rotator Cuff Tendon Defects in Aged Rats Using a Growth Factor Injectable Gel Scaffold., PMID:31784364
Aspirin promotes tenogenic differentiation of tendon stem cells and facilitates tendinopathy healing through regulating the GDF7/Smad1/5 signaling pathway., PMID:31637734
Toxicogenomic analyses of the effects of BDE-47/209, TBBPA/S and TCBPA on early neural development with a human embryonic stem cell in vitro differentiation system., PMID:31326446
Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells., PMID:31324852
Loss of the small GTPase Arl8b results in abnormal development of the roof plate in mouse embryos., PMID:31038803
The TGFβ-signaling pathway and colorectal cancer: associations between dysregulated genes and miRNAs., PMID:29986714
Housekeeping Gene Stability in Human Mesenchymal Stem and Tendon Cells Exposed to Tenogenic Factors., PMID:29676207
Synergistic promoting effects of bone morphogenetic protein 12/connective tissue growth factor on functional differentiation of tendon derived stem cells and patellar tendon window defect regeneration., PMID:29174694
Autogenous Mesenchymal Stem Cells from the Vertebral Body Enhance Intervertebral Disc Regeneration via Paracrine Interaction: An in Vitro Pilot Study., PMID:27075568
The nuclear receptor REV-ERBα represses the transcription of growth/differentiation factor 10 and 15 genes in rat endometrium stromal cells., PMID:26811051
The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk., PMID:26783083
Local rhBMP-12 on an Absorbable Collagen Sponge as an Adjuvant Therapy for Rotator Cuff Repair - A Phase 1, Randomized, Standard of Care Control, Multicenter Study: Safety and Feasibility., PMID:26033972
Multidifferentiation potential of human mesenchymal stem cells from adipose tissue and hamstring tendons for musculoskeletal cell-based therapy., PMID:25565145
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus., PMID:25447851
Identification and characterization of the novel Col10a1 regulatory mechanism during chondrocyte hypertrophic differentiation., PMID:25321476
Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo., PMID:25312837
BMP12 induces tenogenic differentiation of adipose-derived stromal cells., PMID:24155967
Diclofenac and triamcinolone acetonide impair tenocytic differentiation and promote adipocytic differentiation of mesenchymal stem cells., PMID:24004657
The transcription factor Otx2 regulates choroid plexus development and function., PMID:23364326
The effect of growth factors on both collagen synthesis and tensile strength of engineered human ligaments., PMID:22698725
Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation., PMID:22539980
Effect of BMP-12, TGF-β1 and autologous conditioned serum on growth factor expression in Achilles tendon healing., PMID:22124845
[Effect of growth differentiation factor 7 on tenogenic differentiation of bone marrow mesenchymal stem cells of rat in vitro]., PMID:21991820
Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities., PMID:21702718
Treatment with rhBMP12 or rhBMP13 increase the rate and the quality of rat Achilles tendon repair., PMID:21469182
Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering., PMID:21423653
Balanced Shh signaling is required for proper formation and maintenance of dorsal telencephalic midline structures., PMID:21114856
For research use only. Not for human or drug use.
