Catalog No.
YHJ13701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu1069-Glu1331
Predicted molecular weight
32.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7Z406
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Myosin heavy chain 14, Non-muscle myosin heavy chain IIc, Myosin heavy chain, non-muscle IIc, NMHC II-C, MYH14, KIAA2034, Myosin-14
Sodium-Glucose Cotransporter 2 (SGLT2) as a Potential Biomarker and Target in Papillary Renal Cell Carcinoma., PMID:40020263
Increased Matrix Stiffness Promotes Slow Muscle Fibre Regeneration After Skeletal Muscle Injury., PMID:39969079
TMT-labelled quantitative proteomics reveals the mechanism of Rhodotorula mucilaginosa on proteolysis of dry-cured ham: Structural protein degradation, amino acid release and taste improvement., PMID:39848055
A Novel MYH14 Variant Presenting as a New Phenotype of MYH14-Associated Neuromuscular Disorders-Clinicohistologic Findings and Review of the Literature., PMID:39590923
Proteo-transcriptomic profiles reveal genetic mechanisms underlying primary hair follicle development in coarse sheep fetal skin., PMID:39395776
Identification and Validation of Tumor Microenvironment-Associated Signature in Clear-Cell Renal Cell Carcinoma through Integration of DNA Methylation and Gene Expression., PMID:38928496
Sesamolin serves as an MYH14 inhibitor to sensitize endometrial cancer to chemotherapy and endocrine therapy via suppressing MYH9/GSK3β/β-catenin signaling., PMID:38698330
Clinical and genetic features of dominant Essential Tremor in Tuscany, Italy: FUS, CAMTA1, ATXN1 and beyond., PMID:38626532
Pathophysiology of human hearing loss associated with variants in myosins., PMID:38562617
Identification of novel MYH14 variants in families with autosomal dominant sensorineural hearing loss., PMID:38352997
Identification of common genes and pathways underlying imatinib and nilotinib treatment in CML: a Bioinformatics Study., PMID:38117080
Long-stranded non-coding RNAs temporal-specific expression profiles reveal longissimus dorsi muscle development and intramuscular fat deposition in Tianzhu white yak., PMID:38029315
Hereditary etiology of non-syndromic sensorineural hearing loss in the Republic of North Ossetia-Alania., PMID:36743950
Investigation of the effects of downregulation of jumping translocation breakpoint (JTB) protein expression in MCF7 cells for potential use as a biomarker in breast cancer., PMID:36225631
Proteomics Profiling of Osteoporosis and Osteopenia Patients and Associated Network Analysis., PMID:36077598
Heterozygous variants in MYH10 associated with neurodevelopmental disorders and congenital anomalies with evidence for primary cilia-dependent defects in Hedgehog signaling., PMID:35980381
Genetic etiology of non-syndromic hearing loss in Europe., PMID:35044523
A new automated tool to quantify nucleoid distribution within mitochondrial networks., PMID:34815439
Prevalence and Clinical Characteristics of Hearing Loss Caused by MYH14 Variants., PMID:34681017
Regulation of the Expression of the Myosin Heavy Chain (MYH) Gene myh14 in Zebrafish Development., PMID:34490548
Association Analysis of Candidate Gene Polymorphisms and Tinnitus in Young Musicians., PMID:34282101
Nonproductive Splicing Prevents Expression of MYH7b Protein in the Mammalian Heart., PMID:34227390
Cochlear Nerve Canal Stenosis: Association With MYH14 and MYH9 Genes., PMID:33683976
Mapping drug-target interactions and synergy in multi-molecular therapeutics for pressure-overload cardiac hypertrophy., PMID:33589646
Nonmuscle Myosin Heavy Chain ⅡA-Mediated Exosome Release via Regulation of the Rho-Associated Kinase 1/Myosin Light Chains/Actin Pathway., PMID:33363470
Nonmuscle myosin-2 contractility-dependent actin turnover limits the length of epithelial microvilli., PMID:33026933
4-Hydroxyacetophenone modulates the actomyosin cytoskeleton to reduce metastasis., PMID:32848073
A novel MYH14 mutation in a Chinese family with autosomal dominant nonsyndromic hearing loss., PMID:32711451
Nonmuscle myosin 2 regulates cortical stability during sprouting angiogenesis., PMID:32583739
The Progression of Acute Myeloid Leukemia from First Diagnosis to Chemoresistant Relapse: A Comparison of Proteomic and Phosphoproteomic Profiles., PMID:32512867
Myosins and Hearing., PMID:32451864
The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex., PMID:32209652
A Network-Based Bioinformatics Approach to Identify Molecular Biomarkers for Type 2 Diabetes that Are Linked to the Progression of Neurological Diseases., PMID:32041280
Post-lingual non-syndromic hearing loss phenotype: a polygenic case with 2 biallelic mutations in MYO15A and MITF., PMID:31898538
An overview of research trends and genetic polymorphisms for noise-induced hearing loss from 2009 to 2018., PMID:31696427
Neuropathy due to impaired axonal transport of non-fragmented mitochondria in MYH14 mutation carriers., PMID:31653586
Neuropathy due to impaired axonal transport of non-fragmented mitochondria in MYH14 mutation carriers-Authors' reply., PMID:31631044
Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14., PMID:31358530
Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy., PMID:31296530
The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy., PMID:31231018
Systematic Review of Hearing Loss Genes in the African American Population., PMID:31083078
Genetic Inheritance of Late-Onset, Down-Sloping Hearing Loss and Its Implications for Auditory Rehabilitation., PMID:31045651
Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits., PMID:30086768
Replacing nonmuscle myosin 2A with myosin 2C1 permits gastrulation but not placenta vascular development in mice., PMID:30044719
SOX9 is dispensable for the initiation of epigenetic remodeling and the activation of marker genes at the onset of chondrogenesis., PMID:30021842
Quantitative Proteomic Analysis Identifies AHNAK (Neuroblast Differentiation-associated Protein AHNAK) as a Novel Candidate Biomarker for Bladder Urothelial Carcinoma Diagnosis by Liquid-based Cytology., PMID:29950347
Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMA., PMID:29941967
Mammalian nonmuscle myosin II comes in three flavors., PMID:29550471
Identification by proteomics of oviductal sperm-interacting proteins., PMID:29540510
For research use only. Not for human or drug use.
