Catalog No.
YHJ12701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys136-Pro379
Predicted molecular weight
30.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q7L5Y9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HLC-10, E3 ubiquitin-protein transferase MAEA, Erythroblast macrophage protein, Cell proliferation-inducing gene 5 protein, P44EMLP, MAEA, Human lung cancer oncogene 10 protein, EMP, Macrophage erythroblast attacher
Exploring the genomic and transcriptomic profiles of glycemic traits and drug repurposing., PMID:40399988
The interactome of tau phosphorylated at T217 in Alzheimer's disease human brain tissue., PMID:40317322
Metabolic Engineering of E. coli for Enhanced Diols Production from Acetate., PMID:40103233
The E3 ubiquitin ligase MAEA promotes macrophage phagocytosis and inhibits gastrointestinal cancer progression by mediating PARP1 ubiquitination and degradation., PMID:39990651
Microwave-assisted extraction enhances Aquafaba functionality: A high value-added egg white replacer in vegan meringue production., PMID:39897973
Genome-wide screen of Mycobacterium tuberculosis-infected macrophages revealed GID/CTLH complex-mediated modulation of bacterial growth., PMID:39472457
Novel gene fusions in human oropharyngeal carcinoma., PMID:38971117
Snakehead vesiculovirus hijacks SH3RF1 for replication via mediating K63-linked ubiquitination at K264 of the phosphoprotein., PMID:37979762
LAD1 promotes malignant progression by diminishing ubiquitin-dependent degradation of vimentin in gastric cancer., PMID:37718450
Metabolomics of Escherichia coli for Disclosing Novel Metabolic Engineering Strategies for Enhancing Hydrogen and Ethanol Production., PMID:37511377
E3 ligase MAEA-mediated ubiquitination and degradation of PHD3 promotes glioblastoma progression., PMID:36882523
Endocannabinoids, anandamide and 2-AG, regulate mechanosensitivity of mucosal afferents in the Guinea pig bladder., PMID:36858341
maea affects head formation through ß-catenin degradation during early Xenopus laevis development., PMID:36444483
The draft genome sequence of Rhodosporidium toruloides strain Z11, an isolate capable of co-producing lipids and carotenoids from waste molasses., PMID:36276468
The TRPV1 Receptor Is Up-Regulated by Sphingosine 1-Phosphate and Is Implicated in the Anandamide-Dependent Regulation of Mitochondrial Activity in C2C12 Myoblasts., PMID:36232401
Impact of overexpressing NADH kinase on glucoamylase production in Aspergillus niger., PMID:35665816
Oncopeptide MBOP Encoded by LINC01234 Promotes Colorectal Cancer through MAPK Signaling Pathway., PMID:35565466
TBC1D14 inhibits autophagy to suppress lymph node metastasis in head and neck squamous cell carcinoma by downregulating macrophage erythroblast attacher., PMID:35342354
Change in Cofactor Specificity of Oxidoreductases by Adaptive Evolution of an Escherichia coli NADPH-Auxotrophic Strain., PMID:34399608
The plasma peptides of Alzheimer's disease., PMID:34182925
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened., PMID:34161574
MAEA is an E3 ubiquitin ligase promoting autophagy and maintenance of haematopoietic stem cells., PMID:33947846
Plasma biomarkers for prediction of early tumor recurrence after resection of pancreatic ductal adenocarcinoma., PMID:33820913
CB2 cannabinoid receptor agonist selectively inhibits the mechanosensitivity of mucosal afferents in the guinea pig bladder., PMID:33749323
Common variants in MAEA gene contributed the susceptibility to osteoporosis in Han Chinese postmenopausal women., PMID:33423677
Engineering cofactor metabolism for improved protein and glucoamylase production in Aspergillus niger., PMID:33097040
High fat diet induced obesity alters endocannabinoid and ghrelin mediated regulation of components of the endocannabinoid system in nodose ganglia., PMID:32659299
[Identification of a critical region on chromosome 4p16.3 for Wolf-Hirschhorn syndrome-associated fetal growth retardation]., PMID:32619252
Antiemetic Effects of Cannabinoid Agonists in Nonhuman Primates., PMID:32561684
Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment., PMID:32469311
Modulatory effect of methanandamide on gastric vagal afferent satiety signals depends on nutritional status., PMID:32237243
The CTLH Complex in Cancer Cell Plasticity., PMID:31885576
The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan., PMID:31795790
Biphasic effects of methanandamide on murine gastric vagal afferent mechanosensitivity., PMID:31642519
The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation., PMID:31285494
MAEA rs6815464 polymorphism and periodontitis in postmenopausal Japanese females: A cross-sectional study., PMID:31005685
A polymorphism rs6815464 in the macrophage erythroblast attacher gene is associated with low bone mineral density in postmenopausal Japanese women., PMID:30890479
Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands., PMID:30674470
Protectin DX Ameliorates Hepatic Steatosis by Suppression of Endoplasmic Reticulum Stress via AMPK-Induced ORP150 Expression., PMID:29572342
Erythroblast macrophage protein (Emp): Past, present, and future., PMID:29032607
Adenovirus vector-mediated macrophage erythroblast attacher (MAEA) overexpression in primary mouse hepatocytes attenuates hepatic gluconeogenesis., PMID:28955747
Cardiovascular Actions and Clinical Outcomes With Glucagon-Like Peptide-1 Receptor Agonists and Dipeptidyl Peptidase-4 Inhibitors., PMID:28847797
Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex., PMID:28668087
A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants., PMID:28490609
[Effect of Electroacupuncture and Moxibustion on Visceral Pain and Expression of VR 1 and HSP 70 of "Tianshu" (ST 25) Region in Colorectal Distension-induced Visceral Hypersensitivity Rats]., PMID:29071922
Targeted optimization of central carbon metabolism for engineering succinate production in Escherichia coli., PMID:27342774
Type 2 Diabetes Risk Allele UBE2E2 Is Associated With Decreased Glucose-Stimulated Insulin Release in Elderly Chinese Han Individuals., PMID:27175665
Cannabinoid receptor 1 ligands revisited: Pharmacological assessment in the ACTOne system., PMID:26772161
Cannabinoid receptor 1 but not 2 mediates macrophage phagocytosis by G(α)i/o /RhoA/ROCK signaling pathway., PMID:25545473
Molecular phylogeny of a RING E3 ubiquitin ligase, conserved in eukaryotic cells and dominated by homologous components, the muskelin/RanBPM/CTLH complex., PMID:24143168
For research use only. Not for human or drug use.
