Catalog No.
YHJ11301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu489-Ser730
Predicted molecular weight
30.03 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6ZUJ8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BCAP, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, B-cell adapter for phosphoinositide 3-kinase, Phosphoinositide 3-kinase adapter protein 1
Bioinformatics analysis of shared biomarkers and immune pathways of preeclampsia and periodontitis., PMID:40016711
Differential tumor protein expression at follicular lymphoma diagnosis reveals dysregulation of key molecular pathways associated with histological transformation., PMID:39622932
B cell adapter for PI 3-kinase (BCAP) coordinates antigen internalization and trafficking through the B cell receptor., PMID:39546610
Circulating inflammatory and immune response proteins and endometrial cancer risk: a nested case-control study and Mendelian randomization analyses., PMID:39278107
Elucidating sleep disorders: a comprehensive bioinformatics analysis of functional gene sets and hub genes., PMID:38919616
Can inflammatory plasma proteins predict Long COVID or Fatigue severity after SARS-CoV-2 infection?, PMID:38508399
Serum Olink Proteomics-Based Identification of Protein Biomarkers Associated with the Immune Response in Ischemic Stroke., PMID:38319990
New insights into the genetic predisposition of brucellosis and its effect on the gut and vaginal microbiota in goats., PMID:37973848
Bcl-2 inhibition combined with PPARα activation synergistically targets leukemic stem cell-like cells in acute myeloid leukemia., PMID:37644011
Sargentodoxa cuneata and Patrinia villosa extract inhibits LPS-induced inflammation by shifting macrophages polarization through FAK/PI3K/Akt pathway regulation and glucose metabolism reprogramming., PMID:37390878
Identification of the immune-related biomarkers in Behcet's disease by plasma proteomic analysis., PMID:37264476
PI3K-Akt pathway-independent PIK3AP1 identified as a replication inhibitor of the African swine fever virus based on iTRAQ proteomic analysis., PMID:36775023
Analysis of Human Papilloma Virus Content and Integration in Mucoepidermoid Carcinoma., PMID:36366450
PhIP-Seq Reveals Autoantibodies for Ubiquitously Expressed Antigens in Viral Myocarditis., PMID:36101433
Sacha Inchi Oil Press-Cake Protein Hydrolysates Exhibit Anti-Hyperuricemic Activity via Attenuating Renal Damage and Regulating Gut Microbiota., PMID:36010534
Identification of Multiple Hub Genes in Acute Kidney Injury after Kidney Transplantation by Bioinformatics Analysis., PMID:35630098
Study of the inhibitory effect of STAT1 on PDCoV infection., PMID:35033844
MiR-1246 regulates the PI3K/AKT signaling pathway by targeting PIK3AP1 and inhibits thyroid cancer cell proliferation and tumor growth., PMID:34870753
Overexpression of long non-coding RNA WT1-AS or silencing of PIK3AP1 are inhibitory to cervical cancer progression., PMID:34839795
Identification of Gene Co-Expression Networks Associated with Consensus Molecular Subtype-1 of Colorectal Cancer., PMID:34830978
Integrative cBioPortal Analysis Revealed Molecular Mechanisms That Regulate EGFR-PI3K-AKT-mTOR Pathway in Diffuse Gliomas of the Brain., PMID:34209611
BRG1 regulates lipid metabolism in hepatocellular carcinoma through the PIK3AP1/PI3K/AKT pathway by mediating GLMP expression., PMID:34158256
Priming of the cGAS-STING-TBK1 Pathway Enhances LPS-Induced Release of Type I Interferons., PMID:33916318
Frequent somatic TET2 mutations in chronic NK-LGL leukemia with distinct patterns of cytopenias., PMID:33786584
Overexpression of MicroRNA 142-5p Suppresses the Progression of Cervical Cancer through Targeting Phosphoinositol-3-Kinase Adaptor Protein 1 Expression., PMID:33288643
TLR signaling adapter BCAP regulates inflammatory to reparatory macrophage transition by promoting histone lactylation., PMID:33199625
Prediction of a competing endogenous RNA co-expression network as a prognostic marker in glioblastoma., PMID:33047898
Transcriptome sequencing identifies genes associated with invasion of ovarian cancer., PMID:32878513
PIK3AP1 and SPON2 Genes Are Differentially Methylated in Patients With Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis (PFAPA) Syndrome., PMID:32793186
S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion., PMID:32663191
BCAP Regulates Dendritic Cell Maturation Through the Dual-Regulation of NF-κB and PI3K/AKT Signaling During Infection., PMID:32133012
DNA-dependent protein kinase regulates lysosomal AMP-dependent protein kinase activation and autophagy., PMID:31983282
Abnormal methylation of PIK3AP1 was involved in regulating the immune inflammatory response of GES-1 cells induced by Helicobacter pylori., PMID:31980170
Signalling, sorting and scaffolding adaptors for Toll-like receptors., PMID:31889021
A Novel Phosphoinositide-3-kinase Adapter Protein 1 Gene Missense Mutation in Familial Cirrhosis., PMID:31695254
Phosphorylation of the multifunctional signal transducer B-cell adaptor protein (BCAP) promotes recruitment of multiple SH2/SH3 proteins including GRB2., PMID:31527084
Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood-Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters, Receptors or Tight Junction-Related Protein., PMID:31155591
The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1., PMID:31088976
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer., PMID:31078520
Cutting Edge: BCAP Promotes Lupus-like Disease and TLR-Mediated Type I IFN Induction in Plasmacytoid Dendritic Cells., PMID:30936294
BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation., PMID:30093533
B cell adaptor for PI3-kinase (BCAP) modulates CD8+ effector and memory T cell differentiation., PMID:30093532
BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway., PMID:29223746
BCAP inhibits proliferation and differentiation of myeloid progenitors in the steady state and during demand situations., PMID:28087538
Transcriptional profiling of subcutaneous adipose tissue in Italian Large White pigs divergent for backfat thickness., PMID:26931818
Proteomics and Transcriptomics of BJAB Cells Expressing the Epstein-Barr Virus Noncoding RNAs EBER1 and EBER2., PMID:26121143
Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma Multiforme., PMID:25502460
Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer., PMID:24786473
Genome-wide association study of orthostatic hypotension and supine-standing blood pressure changes in two korean populations., PMID:24124408
Nck-mediated recruitment of BCAP to the BCR regulates the PI(3)K-Akt pathway in B cells., PMID:23913047
For research use only. Not for human or drug use.
