Catalog No.
YHJ10601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val22-Ser1268
Predicted molecular weight
141.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6YHK3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CPAMD7, r150, CD109, 150 kDa TGF-beta-1-binding protein, Platelet-specific Gov antigen, CD109 antigen, p180, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7
Three cryo-EM structures of CD109 reveal its mechanism of protease inhibition., PMID:40482031
Identification of EPHB4 as a potential causal gene and therapeutic target for endometriosis using Mendelian randomization., PMID:40450304
IL-6-mediated tumorigenicity and antioxidant state in squamous cell carcinoma cells are driven by CD109 via stabilization of IL-6 receptor-alpha and activation of STAT3/NRF2 pathway., PMID:40317079
Tumor-Derived CD109 Orchestrates Reprogramming of Tumor-Associated Macrophages to Dampen Immune Response., PMID:40220905
Exome sequencing reveals low-frequency and rare variant contributions to multiple sclerosis susceptibility in Turkish families., PMID:40188234
Identification of the Staphylococcus aureus endothelial cell surface interactome by proximity labeling., PMID:40162795
CD109, a master regulator of inflammatory responses., PMID:39990858
4D-DIA Proteomics Uncovers New Insights into Host Salivary Response Following SARS-CoV-2 Omicron Infection., PMID:39803891
Senescence of endothelial cells increases susceptibility to Kaposi's sarcoma-associated herpesvirus infection via CD109-mediated viral entry., PMID:39666389
Microglial upregulation of CD109 expression in spinal cord of amyotrophic lateral sclerosis mouse model and its role in modulating inflammation and TGFβ/SMAD pathway., PMID:39577687
Identification of CD109 in the extracellular vesicles derived from ovarian cancer stem-like cells., PMID:39567205
Endosomal Trafficking Bypassed by the RAB5B-CD109 Interplay Promotes Axonogenesis in KRAS-Mutant Pancreatic Cancer., PMID:39488792
Identification of senescent cell subpopulations by CITE-seq analysis., PMID:39143693
Expression of CD109 in oral squamous cell carcinoma and its clinical significance., PMID:38814222
Asporin and CD109, expressed in the injured neonatal spinal cord, attenuate axonal re-growth in vitro., PMID:38796094
Proteolytic cleavage of the TGFβ co-receptor CD109 changes its conformation, resulting in protease inhibition via activation of its thiol ester, and dissociation from the cell membrane., PMID:38587194
CD109 drives pro-tumorigenic cell properties in human non-small cell lung cancer through interaction with desmoglein-2., PMID:38562713
HPV16 E7 modulates the cell surface expression of MET and CD109 via the AP2 complex., PMID:38485055
CD109 identified in circulating proteomics mitigates postoperative recurrence in chronic rhinosinusitis with nasal polyps by suppressing TGF-β1-induced epithelial-mesenchymal transition., PMID:38442581
CD109 Attenuates Bleomycin-induced Pulmonary Fibrosis by Inhibiting TGF-β Signaling., PMID:38334455
Identification, diversity, and evolution analysis of thioester-containing protein family in Pacific oyster (Crassostrea gigas) and immune response to biotic and abiotic stresses., PMID:38159874
[Expression characteristics and clinical significance of CD109 in de novo acute myeloid leukemia]., PMID:38049323
The possible role furin and furin inhibitors in endometrial adenocarcinoma: A narrative review., PMID:38018319
A sialyltransferases-related gene signature serves as a potential predictor of prognosis and therapeutic response for bladder cancer., PMID:37968767
Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development., PMID:37935281
Comprehensive characterization of pathogenic synovial fluid extracellular vesicles from knee osteoarthritis., PMID:37866785
H3K27 acetylation activated-CD109 evokes 5-fluorouracil resistance in gastric cancer via the JNK/MAPK signaling pathway., PMID:37661780
Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis., PMID:37558884
Metronomic Administration of Topotecan Alone and in Combination with Docetaxel Inhibits Epithelial-mesenchymal Transition in Aggressive Variant Prostate Cancers., PMID:37476073
CLPTM1L is a GPI-anchoring pathway component targeted by HCMV., PMID:37389656
CD109 Promotes Drug Resistance in A2780 Ovarian Cancer Cells by Regulating the STAT3-NOTCH1 Signaling Axis., PMID:37373457
Machine learning approach to screen new diagnostic features of adamantinomatous craniopharyngioma and explore personalised treatment strategies., PMID:37305719
Significance of expression of CD109 in osteosarcoma and its involvement in tumor progression via BMP signaling., PMID:37030166
Mapping Immune Correlates and Surfaceome Genes in BRAF Mutated Colorectal Cancers., PMID:36975409
CD109-regulated mechanical properties of endothelial cells., PMID:36929132
A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer., PMID:36907523
Transcriptomic and proteomic studies suggest the establishment of advanced zonation-like profiles in human-induced pluripotent stem cell-derived liver sinusoidal endothelial cells and carboxypeptidase M-positive liver progenitor cells cocultured in a fluidic microenvironment., PMID:36866738
GABAB receptor activation alters astrocyte phenotype changes induced by trimethyltin via ERK signaling in the dentate gyrus of mice., PMID:36841471
Single cell cortical bone transcriptomics define novel osteolineage gene sets altered in chronic kidney disease., PMID:36777346
CD200 as a Potential New Player in Inflammation during Rotator Cuff Tendon Injury/Repair: An In Vitro Model., PMID:36499497
Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates., PMID:36428765
Mining of transcriptome identifies CD109 and LRP12 as possible biomarkers and deregulation mechanism of T cell receptor pathway in Acute Myeloid Leukemia., PMID:36299526
CD109 Pumps Up Type Two Dendritic Cells for Allergic Responses in the Airways., PMID:36264767
Simultaneous genotyping for human platelet antigen systems and HLA-A and HLA-B loci by targeted next-generation sequencing., PMID:36263028
CD109 on Dendritic Cells Regulates Airway Hyperreactivity and Eosinophilic Airway Inflammation., PMID:36215676
A prognostic six-gene expression risk-score derived from proteomic profiling of the metastatic colorectal cancer secretome., PMID:36134447
Evolution of nacre- and prisms-related shell matrix proteins in the pen shell, Atrina pectinata., PMID:36075178
Molecular characterization of thioester-containing proteins in Biomphalaria glabrata and their differential gene expression upon Schistosoma mansoni exposure., PMID:35967434
CD109 Is a Critical Determinant of EGFR Expression and Signaling, and Tumorigenicity in Squamous Cell Carcinoma Cells., PMID:35954339
A Role of the TEX101 Interactome in the Common Aetiology Behind Male Subfertility and Testicular Germ Cell Tumor., PMID:35774118
For research use only. Not for human or drug use.
