Catalog No.
YHJ09201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser398-Gln568
Predicted molecular weight
22.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6UWW8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Liver carboxylesterase 31 homolog, CES3, Carboxylesterase 3
Multi-omics reveals miR-181a-5p regulates PPAR-driven lipid metabolism in Oral squamous cell carcinoma: Insights from CRISPR/Cas9 knockout models., PMID:40490244
A potential novel biomarker: comprehensive analysis of prognostic value and immune implication of CES3 in colonic adenocarcinoma., PMID:37480527
ACE2 negatively regulates the Warburg effect and suppresses hepatocellular carcinoma progression via reducing ROS-HIF1α activity., PMID:37215979
Identification of lncRNA-miRNA-mRNA Regulatory Network and Therapeutic Agents for Skin Aging by Bioinformatics Analysis., PMID:36719625
Plant produced endotoxin binding recombinant proteins effectively remove endotoxins from protein samples., PMID:36180579
Colchicine stimulates browning via antagonism of GABA receptor B and agonism of β3-adrenergic receptor in 3T3-L1 white adipocytes., PMID:35598717
Nuclear-lipid-droplet proteome: carboxylesterase as a nuclear lipase involved in lipid-droplet homeostasis., PMID:33817385
Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues., PMID:33595329
Effects of methylphenidate on the aggressive behavior, serotonin and dopamine levels, and dopamine-related gene transcription in brain of male Nile tilapia (Oreochromis niloticus)., PMID:31054043
Lipidomic and transcriptomic analysis of western diet-induced nonalcoholic steatohepatitis (NASH) in female Ldlr -/- mice., PMID:30943218
A Unique Role of Carboxylesterase 3 (Ces3) in β-Adrenergic Signaling-Stimulated Thermogenesis., PMID:30862682
Novel regulatory roles of carboxylesterase 3 in lipid metabolism and browning in 3T3-L1 white adipocytes., PMID:30807212
A comparative analysis of label-free liquid chromatography-mass spectrometry liver proteomic profiles highlights metabolic differences between pig breeds., PMID:30208024
Formaldehyde alters triglyceride synthesis and very low-density lipoprotein secretion in a time-dependent manner., PMID:28866046
Global gene expression changes in the prefrontal cortex of rabbits with hypercholesterolemia and/or hypertension., PMID:27890723
Hepatic carboxylesterase 3 (Ces3/Tgh) is downregulated in the early stages of liver cancer development in the rat., PMID:27523631
Tumor-Induced Hyperlipidemia Contributes to Tumor Growth., PMID:27050512
Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages., PMID:24868095
Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat., PMID:24468282
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes., PMID:24362705
Liver-specific cholesteryl ester hydrolase deficiency attenuates sterol elimination in the feces and increases atherosclerosis in ldlr-/- mice., PMID:23744992
Metabolomics identifies an inflammatory cascade involved in dioxin- and diet-induced steatohepatitis., PMID:23140643
Fluoxetine induces hepatic lipid accumulation via both promotion of the SREBP1c-related lipogenesis and reduction of lipolysis in primary mouse hepatocytes., PMID:23137031
Ces3/TGH deficiency improves dyslipidemia and reduces atherosclerosis in Ldlr(-/-) mice., PMID:22872154
Liver specific inactivation of carboxylesterase 3/triacylglycerol hydrolase decreases blood lipids without causing severe steatosis in mice., PMID:22707181
Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing., PMID:22700792
Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity., PMID:21951919
Mammalian carboxylesterase 3: comparative genomics and proteomics., PMID:20422440
Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure., PMID:20197051
Bovine Carboxylesterases: Evidence for Two CES1 and Five Families of CES Genes on Chromosome 18., PMID:20161341
A new class of mammalian carboxylesterase CES6., PMID:20161041
Es-x/Ces1 prevents triacylglycerol accumulation in McArdle-RH7777 hepatocytes., PMID:19651238
Human carboxylesterases: an update on CES1, CES2 and CES3., PMID:19508181
Horse carboxylesterases: evidence for six CES1 and four families of CES genes on chromosome 3., PMID:20403742
In vivo endothelial gene regulation in diabetes., PMID:18423039
Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor., PMID:18289373
Effect of buffer components and carrier solvents on in vitro activity of recombinant human carboxylesterases., PMID:18248745
Hydrolysis of capecitabine to 5'-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide., PMID:15687373
Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a newly expressed carboxylesterase isoenzyme, CES3., PMID:15100172
Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1., PMID:15082749
Carboxylesterases expressed in human colon tumor tissue and their role in CPT-11 hydrolysis., PMID:14581373
Multicopy suppressors of temperature-sensitive mutations of yeast mRNA capping enzyme., PMID:8836740
For research use only. Not for human or drug use.
