Catalog No.
YHJ08501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu27-Asp175
Predicted molecular weight
18.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6UW15
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Regenerating islet-derived protein 3-gamma, Reg III-gamma, Pancreatitis-associated protein 1B, Regenerating islet-derived protein III-gamma, Pancreatitis-associated protein IB, REG III, REG-3-gamma, REG3G, PAP1B, PAP IB, PAP-1B
2'-Fucosyllactose Modulates the Intestinal Immune Response to Gut Microbiota and Buffers Experimental Colitis in Mice: An Integrating Investigation of Colonic Proteomics and Gut Microbiota Analysis., PMID:40501496
Characterization of Mucosal Immune-Related lncRNAs and mRNAs in a Mouse Model of Allergic Conjunctivitis., PMID:40357374
Effects of the regenerating gene family on DSS-induced ulcerative colitis in a mouse model., PMID:40300333
Targeting ubiquitin-independent proteasome with small molecule increases susceptibility in pan-KRAS-mutant cancer models., PMID:40091835
Intraduodenal administration of Reg3g improves gut barrier function and mitigates hepatic steatosis in mice., PMID:39970263
Rotavirus regulates the gut microhabitat immune response through the IL-22/pSTAT3/RegIIIγ signaling pathway, leading to lactose intolerance., PMID:39954663
Effects of Oltipraz on the Glycolipid Metabolism and the Nrf2/HO-1 Pathway in Type 2 Diabetic Mice., PMID:39654602
RegⅢγ promotes the proliferation, and inhibits inflammation response of macrophages by Akt, STAT3 and NF-κB pathways., PMID:39490142
Xylanase enhances gut microbiota-derived butyrate to exert immune-protective effects in a histone deacetylase-dependent manner., PMID:39434145
Gene expression changes in mouse lung induced by subacute inhalation of PM10-rich particulate matter., PMID:39388309
Mechanistic study of fructus aurantii (Quzhou origin) in regulating ileal reg3g in the treatment for NASH., PMID:39098169
Commensal bacterial outer membrane protein A induces interleukin-22 production., PMID:38823020
The imbalance of pulmonary Th17/Treg cells in BALB/c suckling mice infected with respiratory syncytial virus-mediated intestinal immune damage and gut microbiota changes., PMID:38727214
Dissecting the respective roles of microbiota and host genetics in the susceptibility of Card9-/- mice to colitis., PMID:38649950
The role of morphine- and fentanyl-induced impairment of intestinal epithelial antibacterial activity in dysbiosis and its impact on the microbiota-gut-brain axis., PMID:38648368
IL-22-dependent responses and their role during Citrobacter rodentium infection., PMID:38557196
Oral administration of egg ovalbumin allergen induces dysregulation of tryptophan metabolism in sensitized BALB/c mice., PMID:38546528
Antibacterial peptide Reg4 ameliorates Pseudomonas aeruginosa-induced pulmonary inflammation and fibrosis., PMID:38501823
Immune cell-intrinsic Ah receptor facilitates the expression of antimicrobial REG3G in the small intestine., PMID:38358358
Differential Modulation of Mouse Intestinal Organoids with Fecal Luminal Factors from Obese, Allergic, Asthmatic Children., PMID:38255939
Differential gene expression (DGE) analysis in persons with a history of giardiasis., PMID:38170269
Lactobacillus rhamnosus Probio-M9 alleviates OVA-sensitized food allergy through modulating gut microbiota and its metabolism., PMID:37982421
Reg3γ: current understanding and future therapeutic opportunities in metabolic disease., PMID:37524871
Ruminococcus gnavus and Limosilactobacillus reuteri Regulate Reg3γ Expression through Multiple Pathways., PMID:36943156
Bacillus subtilis pretreatment alleviates ethanol-induced acute liver injury by regulating the Gut-liver axis in mice., PMID:36907542
T-cell activation Rho GTPase-activating protein maintains intestinal homeostasis by regulating intestinal T helper cells differentiation through the gut microbiota., PMID:36704549
Evaluation of transcriptomic molecular classification, biological behavior, and clinicopathological features in hepatocellular carcinoma., PMID:36655856
Dysregulated hepatic lipid metabolism and gut microbiota associated with early-stage NAFLD in ASPP2-deficiency mice., PMID:36466835
The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function., PMID:36240758
Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice., PMID:36150609
Multi-Omics Analysis Reveals the Protection of Gasdermin D in Concanavalin A-Induced Autoimmune Hepatitis., PMID:35972273
Milk Fat Globule Membrane Attenuates Acute Colitis and Secondary Liver Injury by Improving the Mucus Barrier and Regulating the Gut Microbiota., PMID:35799795
Prior exposure to microcystin alters host gut resistome and is associated with dysregulated immune homeostasis in translatable mouse models., PMID:35799048
Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia., PMID:35263589
Regenerating islet-derived protein 3 gamma (Reg3g) ameliorates tacrolimus-induced pancreatic β-cell dysfunction in mice by restoring mitochondrial function., PMID:35060126
Free Feeding of CpG-Oligodeoxynucleotide Particles Prophylactically Attenuates Allergic Airway Inflammation and Hyperresponsiveness in Mice., PMID:34867960
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation., PMID:34808192
The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock., PMID:34324837
The Potential Role of REG Family Proteins in Inflammatory and Inflammation-Associated Diseases of the Gastrointestinal Tract., PMID:34281249
Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis., PMID:33970198
Myocardial Accumulations of Reg3A, Reg3γ and Oncostatin M Are Associated with the Formation of Granulomata in Patients with Cardiac Sarcoidosis., PMID:33923774
Temporal overexpression of IL-22 and Reg3γ differentially impacts the severity of experimental autoimmune encephalomyelitis., PMID:33876425
Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis., PMID:33777700
IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice., PMID:33547295
Genetic Dissection of the Regulatory Mechanisms of Ace2 in the Infected Mouse Lung., PMID:33488611
Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22., PMID:33443222
Dietary cellulose induces anti-inflammatory immunity and transcriptional programs via maturation of the intestinal microbiota., PMID:33079623
P. gingivalis Lipopolysaccharide Stimulates the Upregulated Expression of the Pancreatic Cancer-Related Genes Regenerating Islet-Derived 3 A/G in Mouse Pancreas., PMID:33027970
Bacteria-derived long chain fatty acid exhibits anti-inflammatory properties in colitis., PMID:32978245
STING controls intestinal homeostasis through promoting antimicrobial peptide expression in epithelial cells., PMID:32969062