Catalog No.
YHJ08301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser1705-Ile1942
Predicted molecular weight
27.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6UVK1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Chondroitin sulfate proteoglycan 4, CSPG4, Chondroitin sulfate proteoglycan NG2, MCSP, Melanoma chondroitin sulfate proteoglycan, Melanoma-associated chondroitin sulfate proteoglycan
B7-H3 and CSPG4 co-targeting as Pan-CAR-T cell treatment of triple-negative breast cancer., PMID:40425233
Computational analysis of the structural-functional dynamics of a Co-receptor proteoglycan., PMID:40201239
Inherited and de novo variants in young females potentially associated with pelvic organ prolapse., PMID:40157519
Disease pathogenicity in Hutchinson-Gilford progeria syndrome mice: insights from lung-associated alterations., PMID:40128656
Human CSPG4-targeting CAR-macrophages inhibit melanoma growth., PMID:40082557
Clinical evaluation of HuDo-CSPG4 DNA electroporation as adjuvant treatment for canine oral malignant melanoma: comparison of two vaccination protocols., PMID:40059815
Immune regulation differences in Large yellow croaker with varied resistance to Cryptocaryon irritans infection., PMID:39900312
CSPG4 overexpression implicates higher risks of recurrence and tumorigenesis after surgical intervention of vocal fold Leukoplakia., PMID:39863819
Identification of CSPG4 as a Biomarker and Therapeutic Target for Infantile Post-Hemorrhagic Hydrocephalus via Multi-Omics Analysis., PMID:39686677
Glycosaminoglycan Adenogenesis Factors: Immunohistochemical Expression in Endometriosis Tissues Compared with the Endometrium., PMID:39630037
Cspg4 sculpts oligodendrocyte precursor cell morphology., PMID:39566199
CSPG4 involvement in endometrial decidualization contributes to the pathogenesis of preeclampsia†., PMID:39563514
Macrophages producing chondroitin sulfate proteoglycan-4 induce neuro-cardiac junction impairment in Duchenne muscular dystrophy., PMID:39523812
Expression features of targets for anti-glioma CAR-T cell immunotherapy., PMID:39467936
Impact of Chondroitin Sulfate Proteoglycan 4 Pseudogene 12 Genetic Variants on Colorectal Cancer Risk: A Case-Control Study., PMID:39421940
De novo design of mini-protein binders broadly neutralizing Clostridioides difficile toxin B variants., PMID:39358329
Chondroitin Sulfate Proteoglycan 4 (CSPG4) as a Potential Biomarker for Fetal Growth Restriction: Insights from an Umbilical Cord Blood Analysis., PMID:39257129
The cytoglobin-dependent transcriptome in melanoma indicates a protective function associated with oxidative stress, inflammation and cancer-associated pathways., PMID:39107431
Chondroitin sulfate proteoglycan 4 increases invasion of recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma by modifying transforming growth factor-β signalling., PMID:39018437
Application of Proteomics and Machine Learning Methods to Study the Pathogenesis of Diabetic Nephropathy and Screen Urinary Biomarkers., PMID:38949094
CSPG4P12 polymorphism served as a susceptibility marker for esophageal cancer in Chinese population., PMID:38877481
Targeting NG2 relieves the resistance of BRAF-mutant thyroid cancer cells to BRAF inhibitors., PMID:38795180
Chondroitin sulfate proteoglycan 4: An attractive target for antibody-based immunotherapy., PMID:38735753
Hypoxia-associated markers in the prognosis of oral canine melanoma., PMID:38613423
CSPG4-dependent cytotoxicity for C. difficile TcdB is influenced by extracellular calcium and chondroitin sulfate., PMID:38470254
Chondroitin Sulfate Proteoglycan 4 Provides New Treatment Approach to Preventing Peritoneal Dissemination in Ovarian Cancer., PMID:38338902
Chondroitin sulfate modification of CSPG4 regulates the maintenance and differentiation of glioma-initiating cells via integrin-associated signaling., PMID:38309500
Using Human Fetal Neural Stem Cells to Elucidate the Role of the JAK-STAT Cell Signaling Pathway in Oligodendrocyte Differentiation In Vitro., PMID:38227271
Prolonged use of temozolomide leads to increased anxiety and decreased content of aggrecan and chondroitin sulfate in brain tissues of aged rats., PMID:38124768
CSPG4 CAR-redirected Cytokine Induced Killer lymphocytes (CIK) as effective cellular immunotherapy for HLA class I defective melanoma., PMID:37993874
MiR126-targeted-nanoparticles combined with PI3K/AKT inhibitor as a new strategy to overcome melanoma resistance., PMID:37990493
Whole-exome sequencing analysis of patent ductus arteriosus in a Japanese macaque (Macaca fuscata)., PMID:37990472
Combining CSPG4-CAR and CD20-CCR for treatment of metastatic melanoma., PMID:37901209
Comprehensive characterization of pathogenic synovial fluid extracellular vesicles from knee osteoarthritis., PMID:37866785
Screening tumor stage-specific candidate neoantigens in thyroid adenocarcinoma using integrated exome and transcriptome sequencing., PMID:37854594
Targeting the melanoma-associated antigen CSPG4 with HLA-C*07:01-restricted T-cell receptors., PMID:37849763
Exogenous recombinant N-acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) inhibits progression of B16F10 cutaneous melanomas and modulates cell signaling., PMID:37813168
Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB., PMID:37747247
Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment., PMID:37714830
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation., PMID:37699522
Immunohistochemical detection of the chondroitin sulfate proteoglycan 4 protein in primary and metastatic melanoma., PMID:37559576
CSPG4 as a target for the specific killing of triple-negative breast cancer cells by a recombinant SNAP-tag-based antibody-auristatin F drug conjugate., PMID:37432459
Low-density lipoprotein receptor-related protein-1 (LRP1) in the glial lineage modulates neuronal excitability., PMID:37383546
Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice., PMID:37313486
A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma., PMID:37312451
Machine learning-based prognostic modeling of lysosome-related genes for predicting prognosis and immune status of patients with hepatocellular carcinoma., PMID:37275878
Probing the interaction between metastatic breast cancer cells and osteoblasts in a thread-based breast-bone co-culture device., PMID:37255012
Identification of novel urine proteomic biomarkers for high stamina in high-altitude adaptation., PMID:37250129
Overexpression of OLIG2 and MYT1L Transcription Factors Enhance the Differentiation Potential of Human Mesenchymal Stem Cells into Oligodendrocytes., PMID:37232730
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma., PMID:37208128
For research use only. Not for human or drug use.
