Catalog No.
YHJ07801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp167-Lys335
Predicted molecular weight
21.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6Q788
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
APOA5, ApoA-V, RAP3, Regeneration-associated protein 3, Apo-AV, Apolipoprotein A-V, Apolipoprotein A5
Characterization of familial chylomicronemia syndrome in a compound heterozygote for 2 APOA5 nonsense variants., PMID:40500638
Association of CETP, APOA5, IL6, and PON1 Gene Variants with Dyslipidemia and Cardiovascular Risk in a Population from Cauca Department, Colombia., PMID:40428368
Clinical and molecular spectrum of genetic hypertriglyceridaemia in North Indian children: a case series., PMID:40353385
Gene clusters linked to insulin resistance identified in a genome-wide study of the Taiwan Biobank population., PMID:40229288
Gene-Diet Interactions in High-Density Lipoprotein Cholesterol-Related Polymorphisms and Cardiovascular Disease Risk: Insights from the Korean Genome and Epidemiology Study., PMID:40077648
[The regulation and mechanism of apolipoprotein A5 on myocardial lipid deposition]., PMID:40065613
Unveiling circulating targets in pancreatic cancer: Insights from proteogenomic evidence and clinical cohorts., PMID:40060891
Comprehensive analysis of Chinese patients with non-LPL familial chylomicronemia syndrome: Genetic variants, dietary interventions, and clinical insights., PMID:40023655
Ezh2 Shapes T Cell Plasticity to Drive Atherosclerosis., PMID:39917842
Cascade screening of a Pakistani consanguineous familial hypercholesterolemia cohort: Identification of seven new homozygous patients., PMID:39903948
Oxidised Apolipoprotein Peptidome Characterises Metabolic Dysfunction-Associated Steatotic Liver Disease., PMID:39822152
Genetic Variants in Severe Hypertriglyceridemia Among Taiwanese Participants - Insights From Genome-Wide Association and Whole-Exome Sequencing Analyses., PMID:39662927
Identification and functional analysis of novel homozygous LMF1 variants in severe hypertriglyceridemia., PMID:39537501
Can Bone Morphogenetic Protein 1 (BMP1) Be a Potential Biomarker of Obesity?, PMID:39280566
Genetic variants in triglyceride metabolism genes among individuals with hypertriglyceridemia in Colombia., PMID:39278772
Genome-wide association study for metabolic syndrome reveals APOA5 single nucleotide polymorphisms with multilayered effects in Koreans., PMID:39198834
Genetic Polymorphisms and Genetic Risk Scores Contribute to the Risk of Coronary Artery Disease (CAD) in a North Indian Population., PMID:39126122
Sex hormones differently regulate lipid metabolism genes in primary human hepatocytes., PMID:39090659
A Man with Primary Hyperchylomicronemia with Triglyceride Levels Exceeding 11,000 mg/dL Was Well Controlled by Pemafibrate Combined with Dietary Therapy., PMID:39048362
APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease., PMID:38899694
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries., PMID:38880127
Monogenic hypertriglyceridemia and recurrent pancreatitis in a homozygous carrier of a rare APOA5 mutation: a case report., PMID:38872171
Association between APOA5 polymorphisms and susceptibility to metabolic syndrome: a systematic review and meta-analysis., PMID:38867151
Etiology and emerging treatments for familial chylomicronemia syndrome., PMID:38866702
APOA5 alleviates reactive oxygen species to promote oxaliplatin resistance in PIK3CA-mutated colorectal cancer., PMID:38848145
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry., PMID:38795861
Incidental diagnosis of familial apolipoprotein A5 deficiency., PMID:38692986
Evaluation of apolipoprotein A5 variants: A cohort of patients with severe hypertriglyceridemia from Turkiye., PMID:38627169
Carboxyl-terminal sequences in APOA5 are important for suppressing ANGPTL3/8 activity., PMID:38625948
The Apo gene's genetic variants: hidden role in Asian vascular risk., PMID:38625441
Significant but partial lipoprotein lipase functional loss caused by a novel occurrence of rare LPL biallelic variants., PMID:38561841
Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention., PMID:38547584
A unified model for regulating lipoprotein lipase activity., PMID:38521668
Depletion of ApoA5 aggravates spontaneous and diet-induced nonalcoholic fatty liver disease by reducing hepatic NR1D1 in hamsters., PMID:38505614
APOA-5 genetic variant and a hypocaloric diet enriched in ω-6 fatty acids with Mediterranean pattern., PMID:38497884
Identification of a Compound Heterozygous LMF1 Variants in a Patient with Severe Hypertriglyceridemia - Case Report and Literature Review., PMID:38462482
Genetic and biochemical analysis of severe hypertriglyceridemia complicated with acute pancreatitis or with low post-heparin lipoprotein lipase mass., PMID:38346769
Rare and common coding variants in lipid metabolism-related genes and their association with coronary artery disease., PMID:38336686
The pathogenic mutations of APOA5 in Chinese patients with hyperlipidemic acute pancreatitis., PMID:38331899
Cognitive and Functional Change Over Time in Cognitively Healthy Individuals According to Alzheimer Disease Biomarker-Defined Subgroups., PMID:38165338
Genetic variation in apolipoprotein A-V in hypertriglyceridemia., PMID:38117614
Potential drug targets for myocardial infarction identified through Mendelian randomization analysis and Genetic colocalization., PMID:38065874
Angiopoietin-like protein 8: a multifaceted protein instrumental in regulating triglyceride metabolism., PMID:37962908
The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation., PMID:37957317
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus., PMID:37925679
Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen., PMID:37824203
Association of Apolipoprotein A5 Gene Variants with Hyperlipidemic Acute Pancreatitis in Southeastern China., PMID:37768328
Variability of longitudinal triglyceride phenotype in patients heterozygous for pathogenic APOA5 variants., PMID:37586912
Long-term environmental metal exposure is associated with hypomethylation of CpG sites in NFKB1 and other genes related to oncogenesis., PMID:37550793
The East Asian-specific LPL p.Ala288Thr (c.862G > A) missense variant exerts a mild effect on protein function., PMID:37550668
For research use only. Not for human or drug use.
