Catalog No.
YHJ04901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly166-Pro327
Predicted molecular weight
20.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6DKJ4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NRX, Nucleoredoxin, NXN
Nucleoredoxin regulates WNT signaling during pituitary stem cell differentiation., PMID:40044116
Circular RNA NXN (circNXN) promotes diabetic retinopathy by regulating the miR-338-3p/FGFR1 axis., PMID:39988878
Single-Cell RNA Sequencing Reveals LEF1-Driven Wnt Pathway Activation as a Shared Oncogenic Program in Hepatoblastoma and Medulloblastoma., PMID:39851951
Molecular characterization, transcriptional profiling, and antioxidant activity assessment of nucleoredoxin (NXN) as a novel member of thioredoxin from red-lip mullet (Planiliza haematocheilus)., PMID:39736406
Molecules That Have Rarely Been Studied in Lymphatic Endothelial Cells., PMID:39596293
A model of alcoholic liver disease based on different hepatotoxics leading to liver cancer., PMID:38621424
Nucleoredoxin Redox Interactions Are Sensitized by Aging and Potentiated by Chronic Alcohol Consumption in the Mouse Liver., PMID:38539791
Size-dependent toxicity of polystyrene microplastics on the gastrointestinal tract: Oxidative stress related-DNA damage and potential carcinogenicity., PMID:38135073
Hi-BDiSCO: folding 3D mesoscale genome structures from Hi-C data using brownian dynamics., PMID:38015443
Association of Blood-Based DNA Methylation Markers With Late-Onset Alzheimer Disease: A Potential Diagnostic Approach., PMID:37827850
Cold avoidance and heat pain hypersensitivity in neuronal nucleoredoxin knockout mice., PMID:36126861
NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3., PMID:35927236
Is Nucleoredoxin a Master Regulator of Cellular Redox Homeostasis? Its Implication in Different Pathologies., PMID:35453355
NXN Gene Epigenetic Changes in an Adult Neurogenesis Model of Alzheimer's Disease., PMID:35406633
Binary Matrix Method to Enumerate, Hierarchically Order, and Structurally Classify Peptide Aggregation., PMID:35232014
Novel pathogenic variants and quantitative phenotypic analyses of Robinow syndrome: WNT signaling perturbation and phenotypic variability., PMID:35047859
Impairment of lysosomal function by Clostridioides difficile TcdB., PMID:34931374
Common and mutation specific phenotypes of KRAS and BRAF mutations in colorectal cancer cells revealed by integrative -omics analysis., PMID:34233735
Reduced exploratory behavior in neuronal nucleoredoxin knockout mice., PMID:34198070
Nucleoredoxin Knockdown in SH-SY5Y Cells Promotes Cell Renewal., PMID:33805811
The Carboxyl-Terminal Penta-Peptide Repeats of Major Royal Jelly Protein 3 Enhance Cell Proliferation., PMID:33268709
Flightless-I is a potential biomarker for the early detection of alcoholic liver disease., PMID:33166508
Novel pathogenic genomic variants leading to autosomal dominant and recessive Robinow syndrome., PMID:33048444
Neurocognitive, adaptive, and psychosocial functioning in individuals with Robinow syndrome., PMID:32954672
Nucleoredoxin interaction with flightless-I/actin complex is differentially altered in alcoholic liver disease., PMID:32524749
Protein velocity and acceleration from single-cell multiomics experiments., PMID:32070398
Therapeutic Application of Micellar Solubilized Xanthohumol in a Western-Type Diet-Induced Mouse Model of Obesity, Diabetes and Non-Alcoholic Fatty Liver Disease., PMID:30999670
Ethanol targets nucleoredoxin/dishevelled interactions and stimulates phosphatidylinositol 4-phosphate production in vivo and in vitro., PMID:30125555
CYP2D6 basic genotyping as a potential tool to improve the antiemetic efficacy of ondansetron in prophylaxis of postoperative nausea and vomiting., PMID:30058787
Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy., PMID:29470513
WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome., PMID:29276006
Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner., PMID:29037191
Proteomic and transcriptomic studies of HBV-associated liver fibrosis of an AAV-HBV-infected mouse model., PMID:28830339
Glucosyltransferase-dependent and -independent effects of TcdB on the proteome of HEp-2 cells., PMID:28612519
Toxin A of the nosocomial pathogen Clostridium difficile induces primary effects in the proteome of HEp-2 cells., PMID:27860399
Genome-wide DNA methylation patterns in CD4+ T cells from Chinese Han patients with rheumatoid arthritis., PMID:27585642
Hairpin formation promoted by the heterochiral dinipecotic acid segment: A DFT study., PMID:26015319
Phosphorescent biscyclometallated iridium(III) ethylenediamine complexes functionalised with polar ester or carboxylate groups as bioimaging and visualisation reagents., PMID:25522324
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk., PMID:24836286
Structures of complexes of a metal-independent glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-acetylgalactosamine (UDP-GalNAc) and its hydrolysis products., PMID:24459149
Fibrogenic actions of acetaldehyde are β-catenin dependent but Wingless independent: a critical role of nucleoredoxin and reactive oxygen species in human hepatic stellate cells., PMID:23880292
Identification of cilia genes that affect cell-cycle progression using whole-genome transcriptome analysis in Chlamydomonas reinhardtti., PMID:23604077
NXN-188, a selective nNOS inhibitor and a 5-HT1B/1D receptor agonist, inhibits CGRP release in preclinical migraine models., PMID:23155193
Emerging treatment for chronic migraine and refractory chronic migraine., PMID:22862686
Gastrodia elata Blume (tianma) mobilizes neuro-protective capacities., PMID:22773961
Digital staining for histopathology multispectral images by the combined application of spectral enhancement and spectral transformation., PMID:22256200
Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer., PMID:20682712
Triptan-induced enhancement of neuronal nitric oxide synthase in trigeminal ganglion dural afferents underlies increased responsiveness to potential migraine triggers., PMID:20627971
Discovery of candidate disease genes in ENU-induced mouse mutants by large-scale sequencing, including a splice-site mutation in nucleoredoxin., PMID:20011118
Elementary network reconstruction: a framework for the analysis of regulatory networks in biological systems., PMID:20004670
For research use only. Not for human or drug use.
