Catalog No.
YHJ04501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr960-Val1192
Predicted molecular weight
29.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q6AWC2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein WWC2, WWC2, BOMB, WW domain-containing protein 2, BH-3-only member B
CLK1 Activates YAP to Promote Intrahepatic Cholangiocarcinogenesis., PMID:39693605
m6A-modified circXPO1 accelerates colorectal cancer progression via interaction with FMRP to promote WWC2 mRNA decay., PMID:39402642
WWC2 modulates GABAA-receptor-mediated synaptic transmission, revealing class-specific mechanisms of synapse regulation by WWC family proteins., PMID:39388350
Cuproptosis-related lncRNA signature as a prognostic tool and therapeutic target in diffuse large B cell lymphoma., PMID:38839842
Modulation of GABA A receptor trafficking by WWC2 reveals class-specific mechanisms of synapse regulation by WWC family proteins., PMID:38559047
WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT., PMID:37528078
WWC2 expression in the testis: Implications for spermatogenesis and male fertility., PMID:37086090
Identification of healthspan-promoting genes in Caenorhabditis elegans based on a human GWAS study., PMID:35748965
Constructing a Novel Signature Based on Immune-Related lncRNA to Improve Prognosis Prediction of Cervical Squamous Cell Carcinoma Patients., PMID:35075611
Identification of Differentially Expressed and Prognostic lncRNAs for the Construction of ceRNA Networks in Lung Adenocarcinoma., PMID:34987577
Lack of WWC2 Protein Leads to Aberrant Angiogenesis in Postnatal Mice., PMID:34070186
The Hippo pathway component Wwc2 is a key regulator of embryonic development and angiogenesis in mice., PMID:33483469
WWC Proteins: Important Regulators of Hippo Signaling in Cancer., PMID:33467643
Identification of Crucial lncRNAs, miRNAs, mRNAs, and Potential Therapeutic Compounds for Polycystic Ovary Syndrome by Bioinformatics Analysis., PMID:33224973
miR-21-5p promotes lung adenocarcinoma cell proliferation, migration and invasion via targeting WWC2., PMID:32623387
MicroRNA-10a promotes epithelial-to-mesenchymal transition and stemness maintenance of pancreatic cancer stem cells via upregulating the Hippo signaling pathway through WWC2 inhibition., PMID:32542845
Down-Regulation of LINC00460 Represses Metastasis of Colorectal Cancer via WWC2., PMID:31541369
LncRNA WWC2-AS1 functions AS a novel competing endogenous RNA in the regulation of FGF2 expression by sponging miR-16 in radiation-induced intestinal fibrosis., PMID:31262262
Bone marrow fibroblasts overexpress miR-27b and miR-214 in step with multiple myeloma progression, dependent on tumour cell-derived exosomes., PMID:30357841
WWC2 is an independent prognostic factor and prevents invasion via Hippo signalling in hepatocellular carcinoma., PMID:28815883
Evolutionary and molecular facts link the WWC protein family to Hippo signaling., PMID:24682284
Exome sequencing in a family with restless legs syndrome., PMID:23192925
Function and cancer genomics of FAT family genes (review)., PMID:23076869
For research use only. Not for human or drug use.
