Catalog No.
YHJ04201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala4069-Gly4393
Predicted molecular weight
38.21 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q685J3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MUC-3, MUC-17, MUC17, Small intestinal mucin-3, Mucin-17, MUC3
Construction of Bispecific T-Cell Engager Radiotracer and Its Micro-PET Evaluation in Pancreatic Cancer., PMID:40146904
Integrated Analysis of WES and scRNA-Seq Data Reveals the Genetic Basis of Immune Dysregulation in Unexplained Recurrent Pregnancy Loss., PMID:40066928
Deoxynivalenol modulated mucin expression and proinflammatory cytokine production, affecting susceptibility to enteroinvasive Escherichia coli infection in intestinal epithelial cells., PMID:39980277
Relationship between mucin gene polymorphisms and different types of gallbladder stones., PMID:39885433
Development of a Caco-2-based intestinal mucosal model to study intestinal barrier properties and bacteria-mucus interactions., PMID:39714032
MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease., PMID:39699961
The MYO1B and MYO5B motor proteins and the sorting nexin SNX27 regulate apical targeting of membrane mucin MUC17 in enterocytes., PMID:39661054
Identification and validation of serum MUC17 as a non-invasive early warning biomarker for screening of gastric intraepithelial neoplasia., PMID:39580962
MUC17 Is a Potential New Prognostic Biomarker and Promotes Pancreatic Cancer Progression in Obstructive Jaundice., PMID:39396510
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response., PMID:39123229
[Clinicopathological and molecular genetic features of Crohn's disease]., PMID:38556818
Characterizing and forecasting neoantigens-resulting from MUC mutations in COAD., PMID:38539235
Mucin Expression Profiles in Ulcerative Colitis: New Insights on the Histological Mucosal Healing., PMID:38339134
Polypeptide N-Acetylgalactosaminyltransferase 14 (GALNT14) as a Chemosensitivity-Related Biomarker for Osteosarcoma., PMID:38024474
MUC17 mutations and methylation are associated with poor prognosis in adult-type diffuse glioma patients., PMID:37562166
Variants of Human Mucin Genes in Clear Cell Renal Cell Carcinoma and their Potential Prognostic and Predictive Values., PMID:37283258
The MYO1B and MYO5B motor proteins and the SNX27 sorting nexin regulate membrane mucin MUC17 trafficking in enterocytes., PMID:36945389
Acquired resistance to EGFR-TKIs in NSCLC mediates epigenetic downregulation of MUC17 by facilitating NF-κB activity via UHRF1/DNMT1 complex., PMID:36778111
Investigation of biomarkers in Endometriosis-associated infertility: Systematic Review., PMID:36477241
DUSP5 and PHLDA1 mutations in mature cystic teratomas of the ovary identified on whole-exome sequencing may explain teratoma characteristics., PMID:36289533
Discovery of a MUC3B gene reconstructs the membrane mucin gene cluster on human chromosome 7., PMID:36256656
Molecular classification of human papillomavirus-positive cervical cancers based on immune signature enrichment., PMID:36203656
Identification and Validation of Immune Infiltration Phenotypes in Laryngeal Squamous Cell Carcinoma by Integrative Multi-Omics Analysis., PMID:35281069
High frequency of PDGFRA and MUC family gene mutations in diffuse hemispheric glioma, H3 G34-mutant: a glimmer of hope?, PMID:35109850
Bile cytology diagnosis in challenging cases: Validation of diagnostic bile cytology criteria and extensive study for immunocytochemical markers., PMID:34981669
Bioinformatic Analysis of Immune Significance of RYR2 Mutation in Breast Cancer., PMID:34888385
Combination of 35-Gene Mutation Profile and Radiotherapy Dosimetry Predicts the Therapeutic Outcome of Definitive Chemoradiation in Patients With Esophageal Squamous Cell Carcinoma., PMID:34513706
Systems Immunology Analysis Reveals the Contribution of Pulmonary and Extrapulmonary Tissues to the Immunopathogenesis of Severe COVID-19 Patients., PMID:34262555
IL-22 promotes the formation of a MUC17 glycocalyx barrier in the postnatal small intestine during weaning., PMID:33596425
Skin transcriptome, tissue distribution of mucin genes and discovery of simple sequence repeats in crucian carp (Carassius auratus)., PMID:32885862
Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants., PMID:32734521
Comprehensive Cohort Analysis of Mutational Spectrum in Early Onset Breast Cancer Patients., PMID:32731431
Transcriptional Signatures That Define Ulcerative Colitis in Remission., PMID:32322884
An intestinal model with a finger-like villus structure fabricated using a bioprinting process and collagen/SIS-based cell-laden bioink., PMID:32194815
EGF-Containing Membrane-Bound Mucins: A Hidden ErbB2 Targeting Pathway?, PMID:32027502
Genomic and Expression Analyses Define MUC17 and PCNX1 as Predictors of Chemotherapy Response in Breast Cancer., PMID:31879365
Analysis of TGCA data reveals genetic and epigenetic changes and biological function of MUC family genes in colorectal cancer., PMID:31773991
The human transmembrane mucin MUC17 responds to TNFα by increased presentation at the plasma membrane., PMID:31387973
Mucin 17 inhibits the progression of human gastric cancer by limiting inflammatory responses through a MYH9-p53-RhoA regulatory feedback loop., PMID:31262330
Effects of chlorogenic acid, epicatechin gallate, and quercetin on mucin expression and secretion in the Caco-2/HT29-MTX cell model., PMID:30847127
Untouchable genes in the human genome: Identifying ideal targets for cancer treatment., PMID:30803560
Epigenetic downregulation of MUC17 by H. pylori infection facilitates NF-κB-mediated expression of CEACAM1-3S in human gastric cancer., PMID:30778796
Non-Invasive Evaluation of Extracellular Matrix Formation in the Intestinal Epithelium., PMID:30417287
Genomic landscape and mutational impacts of recurrently mutated genes in cancers., PMID:30107644
Germline cytoskeletal and extra-cellular matrix-related single nucleotide variations associated with distinct cancer survival rates., PMID:29778426
Study of mucin turnover in the small intestine by in vivo labeling., PMID:29636525
Peptidomic Analysis of Female Reproductive Tract Secretion to Identify Putative Anti-Infection Peptides in the Female Genital System via Nanotechnologies., PMID:29463379
Identification of Sets of Cytoskeletal Related and Adhesion-related Coding Region Mutations in the TCGA Melanoma Dataset that Correlate with a Negative Outcome., PMID:28659724
Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer., PMID:28052300
Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients., PMID:27803053
For research use only. Not for human or drug use.
