Catalog No.
YHJ03101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe138-Leu248
Predicted molecular weight
15.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5TB30
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DEPDC1, DEPDC1A, DEP domain-containing protein 1A
DEP domain‑containing 1 is a prognostic biomarker associated with the cell cycle in gliomas., PMID:40247989
YY1-mediated DUXAP8 facilitates HCC progression via modulating DEPDC1 expression., PMID:39992478
Exploring shared pathogenesis of multiple myeloma and osteoporosis via bioinformatic analysis., PMID:39943780
Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations., PMID:39391317
Roles of DEPDC1 in various types of cancer (Review)., PMID:39296974
DEPDC1 as a metabolic target regulates glycolysis in renal cell carcinoma through AKT/mTOR/HIF1α pathway., PMID:39068164
DEPDC1 affects autophagy-dependent glycolysis levels in human osteosarcoma cells by modulating RAS/ERK signaling through TTK., PMID:39016842
FOXM1/DEPDC1 feedback loop promotes hepatocarcinogenesis and represents promising targets for cancer therapy., PMID:39004911
Exosomal miR-130b-3p suppresses metastasis of non-small cell lung cancer cells by targeting DEPDC1 via TGF-β signaling pathway., PMID:38960258
DEPDC1B is a Novel Direct Target of B-Myb and Contributes to Malignant Progression and Immune Infiltration in Lung Adenocarcinoma., PMID:38940035
Comprehensive analysis and validation reveal DEPDC1 as a potential diagnostic biomarker associated with tumor immunity in non-small-cell lung cancer., PMID:38564630
Targeting DEP domain containing 1 in anaplastic thyroid carcinoma: Implications for stemness regulation and malignant phenotype suppression., PMID:38449652
Machine Learning Developed a MYC Expression Feature-Based Signature for Predicting Prognosis and Chemoresistance in Pancreatic Adenocarcinoma., PMID:38245886
Genome-wide DNA methylation of lesional and peri-lesional skin in vitiligo: a comparative and integrated analysis of multi-omics in Chinese population., PMID:38182908
S100A16 cooperates with DEPDC1 to promote the progression and angiogenesis of nephroblastoma through PI3K/Akt/mTOR pathway., PMID:37955537
Molecular Characterization of Cuproptosis-related lncRNAs: Defining Molecular Subtypes and a Prognostic Signature of Ovarian Cancer., PMID:37528285
Bioinformatics analysis of the pathogenic link between Epstein-Barr virus infection, systemic lupus erythematosus and diffuse large B cell lymphoma., PMID:37072474
High-throughput RNA-sequencing reveals novel targets of tofacitinib in the treatment of rheumatoid arthritis., PMID:36995321
Identification of Core Genes Shared by Endometrial Cancer and Ovarian Cancer Using an Integrated Approach., PMID:36905262
DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway., PMID:36849972
Identification of a Five Immune Term Signature for Prognosis and Therapy Options (Immunotherapy versus Targeted Therapy) for Patients with Hepatocellular Carcinoma., PMID:36785674
Glycolysis-Related Gene Analyses Indicate That DEPDC1 Promotes the Malignant Progression of Oral Squamous Cell Carcinoma via the WNT/β-Catenin Signaling Pathway., PMID:36768316
Integrative transcriptome analysis of triple negative breast cancer profiles for identification of druggable targets., PMID:36617953
DEPDC1 as a crucial factor in the progression of human osteosarcoma., PMID:36479633
Silencing eL31 suppresses the progression of colorectal cancer via targeting DEPDC1., PMID:36309731
SIRT1 enhances oxaliplatin resistance in colorectal cancer through microRNA-20b-3p/DEPDC1 axis., PMID:36200529
FOXM1 is regulated by DEPDC1 to facilitate development and metastasis of oral squamous cell carcinoma., PMID:36072787
FOXO3a‑modulated DEPDC1 promotes malignant progression of nephroblastoma via the Wnt/β‑catenin signaling pathway., PMID:35795985
Identification of Core Genes and Screening of Potential Targets in Intervertebral Disc Degeneration Using Integrated Bioinformatics Analysis., PMID:35711934
Long non-coding RNA DEPDC1-AS1 promotes proliferation and migration of human gastric cancer cells HGC-27 via the human antigen R-F11R pathway., PMID:35466755
Identification of potential key genes and functional role of CENPF in osteosarcoma using bioinformatics and experimental analysis., PMID:34934449
Linc-ROR facilitates progression and angiogenesis of hepatocellular carcinoma by modulating DEPDC1 expression., PMID:34741030
Artemisia argyi Essential Oil Inhibits Hepatocellular Carcinoma Metastasis via Suppression of DEPDC1 Dependent Wnt/β-Catenin Signaling Pathway., PMID:34268303
ALPK2 acts as tumor promotor in development of bladder cancer through targeting DEPDC1A., PMID:34210956
In silico analysis of differentially expressed genesets in metastatic breast cancer identifies potential prognostic biomarkers., PMID:34172056
[DEPDC1 is Highly Expressed in Lung Adenocarcinoma and Promotes Tumor Cell Proliferation]., PMID:34134185
Identification of Prognostic Biomarkers and Correlation With Immune Infiltrates in Hepatocellular Carcinoma Based on a Competing Endogenous RNA Network., PMID:34093635
Long noncoding RNA KTN1 antisense RNA 1exerts an oncogenic function in lung adenocarcinoma by regulating DEP domain containing 1 expression via activating epithelial-mesenchymal transition., PMID:33491970
Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCR., PMID:33403046
DEPDC1 upregulation promotes cell proliferation and predicts poor prognosis in patients with gastric cancer., PMID:33361586
The effect of a novel glycolysis-related gene signature on progression, prognosis and immune microenvironment of renal cell carcinoma., PMID:33287763
Overexpression of gene DEP domain containing 1 and its clinical prognostic significance in colorectal cancer., PMID:33140894
DEPDC1 up-regulates RAS expression to inhibit autophagy in lung adenocarcinoma cells., PMID:33021072
Identification of epithelial-mesenchymal transition-related circRNA-miRNA-mRNA ceRNA regulatory network in breast cancer., PMID:32825956
Identification of biomarkers in colon cancer based on bioinformatic analysis., PMID:35117850
NNK-mediated upregulation of DEPDC1 stimulates the progression of oral squamous cell carcinoma by inhibiting CYP27B1 expression., PMID:32642287
Key genes involved in cell cycle arrest and DNA damage repair identified in anaplastic thyroid carcinoma using integrated bioinformatics analysis., PMID:35117787
Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients., PMID:32500232
STAT1-induced upregulation of lncRNA KTN1-AS1 predicts poor prognosis and facilitates non-small cell lung cancer progression via miR-23b/DEPDC1 axis., PMID:32396871
DEP Domain Containing 1 Promotes Proliferation, Invasion, and Epithelial-Mesenchymal Transition in Colorectal Cancer by Enhancing Expression of Suppressor of Zest 12., PMID:32343606
For research use only. Not for human or drug use.
