Catalog No.
YHJ02101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val645-Gly888
Predicted molecular weight
29.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q5JZY3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EPHA10, Ephrin type-A receptor 10
Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer., PMID:39965532
The mechanism of all-trans retinoic acid-induced cleft palate may be related to the novel ENSMUST00000159153-miR-137-5p-Wnt7a and ENSMUST000000236086-miR-34b-3p-EphA10/TRPM2 ceRNA crosstalk., PMID:39710122
Comprehensive analysis of Epha10 as a predictor of clinical prognosis and immune checkpoint therapy efficacy in non-small cell lung cancer., PMID:39179608
Prognostic microRNAs as biomarkers for prostate cancer., PMID:38554337
Pictilisib-Induced Resistance Is Mediated through FOXO1-Dependent Activation of Receptor Tyrosine Kinases in Mucinous Colorectal Adenocarcinoma Cells., PMID:37569713
EPH/Ephrin-Targeting Treatment in Breast Cancer: A New Chapter in Breast Cancer Therapy., PMID:36499598
A non-coding variant in 5' untranslated region drove up-regulation of pseudo-kinase EPHA10 and caused non-syndromic hearing loss in humans., PMID:36048850
EphA10 drives tumor progression and immune evasion by regulating the MAPK/ERK cascade in lung adenocarcinoma., PMID:35839564
EphrinA3 is a key regulator of malignant behaviors and a potential prognostic factor in lung adenocarcinoma., PMID:35770949
Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer., PMID:35278434
Artesunate-induced Cellular Effects Are Mediated by Specific EPH Receptors and Ephrin Ligands in Breast Carcinoma Cells., PMID:34949656
The intracellular domains of the EphB6 and EphA10 receptor tyrosine pseudokinases function as dynamic signalling hubs., PMID:34431498
Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration., PMID:33990369
Expression Pattern and Prognostic Value of EPHA/EFNA in Breast Cancer by Bioinformatics Analysis: Revealing Its Importance in Chemotherapy., PMID:33977106
Radiomics and gene expression profile to characterise the disease and predict outcome in patients with lung cancer., PMID:33959797
Galectin‑9 suppresses the tumor growth of colon cancer in vitro and in vivo., PMID:33907832
Ephrin A4-ephrin receptor A10 signaling promotes cell migration and spheroid formation by upregulating NANOG expression in oral squamous cell carcinoma cells., PMID:33436772
Stem-like Cells from Invasive Breast Carcinoma Cell Line MDA-MB-231 Express a Distinct Set of Eph Receptors and Ephrin Ligands., PMID:33099474
The catalytically defective receptor protein tyrosine kinase EphA10 promotes tumorigenesis in pancreatic cancer cells., PMID:32644283
The plasma peptides of sepsis., PMID:32636717
Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases., PMID:32619402
Transcriptional Signatures That Define Ulcerative Colitis in Remission., PMID:32322884
Cataloguing the dead: breathing new life into pseudokinase research., PMID:32053275
Anti-diabetic drug metformin inhibits cell proliferation and tumor growth in gallbladder cancer via G0/G1 cell cycle arrest., PMID:31815765
Eph receptor signalling: from catalytic to non-catalytic functions., PMID:31406248
Molecular dissection of cone photoreceptor-enriched genes encoding transmembrane and secretory proteins., PMID:30260491
[Development of a Fundamental Technology to Seek Drug Targets, and Its Application to Cancer Targeting Therapy]., PMID:29962467
Overcoming Multidrug Resistance by Codelivery of MDR1-Targeting siRNA and Doxorubicin Using EphA10-Mediated pH-Sensitive Lipoplexes: In Vitro and In Vivo Evaluation., PMID:29798663
Juxtacrine Signaling Inhibits Antitumor Immunity by Upregulating PD-L1 Expression., PMID:29789418
Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine-docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo., PMID:29513049
Isoform expression patterns of EPHA10 protein mediate breast cancer progression by regulating the E-Cadherin and β-catenin complex., PMID:28427223
Anti-EphA10 antibody-conjugated pH-sensitive liposomes for specific intracellular delivery of siRNA., PMID:27574425
EPHA7 and EPHA10 Physically Interact and Differentially Co-localize in Normal Breast and Breast Carcinoma Cell Lines, and the Co-localization Pattern Is Altered in EPHB6-expressing MDA-MB-231 Cells., PMID:27566654
[Challenge to the Development of Molecular Targeted Therapy against a Novel Target Candidate Identified by Antibody Proteomics Technology]., PMID:26831784
A Novel Bispecific Antibody against Human CD3 and Ephrin Receptor A10 for Breast Cancer Therapy., PMID:26678395
Antitumor effect of metformin on cholangiocarcinoma: In vitro and in vivo studies., PMID:26398221
Extracellular superoxide dismutase regulates the expression of small gtpase regulatory proteins GEFs, GAPs, and GDI., PMID:25751262
Generation and characterization of a bispecific diabody targeting both EPH receptor A10 and CD3., PMID:25528586
Ligand stimulation induces clathrin- and Rab5-dependent downregulation of the kinase-dead EphB6 receptor preceded by the disruption of EphB6-Hsp90 interaction., PMID:25152371
Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers., PMID:24946238
Eph receptor A10 has a potential as a target for a prostate cancer therapy., PMID:24924629
Expression of Eph receptor A10 is correlated with lymph node metastasis and stage progression in breast cancer patients., PMID:24403271
PreImplantation factor (PIF*) promotes embryotrophic and neuroprotective decidual genes: effect negated by epidermal growth factor., PMID:26085845
Increased EphA/ephrinA expression in hippocampus of pilocarpine treated mouse., PMID:23352741
A paradigm shift in EPH receptor interaction: biological relevance of EPHB6 interaction with EPHA2 and EPHB2 in breast carcinoma cell lines., PMID:21737611
Dancing with the dead: Eph receptors and their kinase-null partners., PMID:21455264
Expression profile of Eph receptors and ephrin ligands in healthy human B lymphocytes and chronic lymphocytic leukemia B-cells., PMID:18819711
Comparative integromics on Eph family., PMID:16596241
Potential clinical relevance of Eph receptors and ephrin ligands expressed in prostate carcinoma cell lines., PMID:16516143
Characterization of a novel Eph receptor tyrosine kinase, EphA10, expressed in testis., PMID:15777695
For research use only. Not for human or drug use.
