Catalog No.
YHH91301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly165-Phe439
Predicted molecular weight
31.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q53RD9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FBLN7, TM14, FIBL-7, Fibulin-7
The pericellular function of Fibulin-7 in the adhesion of oligodendrocyte lineage cells to neuronal axons during CNS myelination., PMID:39809135
FBLN7 mediates vascular smooth muscle cell phenotype switching and vascular remodeling in hypertension., PMID:39659565
An in-silico study reveals that a C-terminal fragment of the adhesion protein Fibulin7 (Fbln7-C) regulates the activation of integrin α5β1 through dynamics of VWA and the hybrid domain in the β1 subunit., PMID:39578974
RNA-binding proteins potentially regulate alternative splicing of immune/inflammatory-associated genes during the progression of generalized pustular psoriasis., PMID:39158708
Exome sequencing identifies novel genetic variants associated with varicose veins., PMID:38980841
A synthetic bioactive peptide of the C-terminal fragment of adhesion protein Fibulin7 attenuates the inflammatory functions of innate immune cells in LPS-induced systemic inflammation., PMID:38836870
Fibulin7 Mediated Pathological Cardiac Remodeling through EGFR Binding and EGFR-Dependent FAK/AKT Signaling Activation., PMID:37344348
Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration., PMID:37009470
Fibulin7 aggravates calcium oxalate-induced acute kidney injury by binding to calcium oxalate crystals., PMID:36370444
Novel progressive acrodysostosis-like skeletal dysplasia, cerebellar atrophy, and ichthyosis., PMID:32783359
Immunomodulation via macrophages to fight solid tumor malignancies., PMID:32578301
The role of adhesion protein Fibulin7 in development and diseases., PMID:32429873
A C-terminal fragment of adhesion protein Fibulin7 regulates neutrophil migration and functions and improves survival in LPS induced systemic inflammation., PMID:32388247
A C-terminal fragment of adhesion protein fibulin-7 inhibits growth of murine breast tumor by regulating macrophage reprogramming., PMID:32297473
Fibulin-7 C-terminal fragment and its active synthetic peptide suppress choroidal and retinal neovascularization., PMID:32017943
Hypothalamic transcriptome of tame and aggressive silver foxes (Vulpes vulpes) identifies gene expression differences shared across brain regions., PMID:31605445
Possible role of differentially expressing novel protein markers (ligatin and fibulin-7) in human aqueous humor and trabecular meshwork tissue in glaucoma progression., PMID:30958601
Fibulin-7 is overexpressed in glioblastomas and modulates glioblastoma neovascularization through interaction with angiopoietin-1., PMID:30924128
Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity., PMID:30518776
Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice., PMID:29730503
Cell adhesion protein fibulin-7 and its C-terminal fragment negatively regulate monocyte and macrophage migration and functions in vitro and in vivo., PMID:29634368
Spiroplasma eriocheiris Adhesin-Like Protein (ALP) Interacts with Epidermal Growth Factor (EGF) Domain Proteins to Facilitate Infection., PMID:28184355
Identification of peptides derived from the C-terminal domain of fibulin-7 active for endothelial cell adhesion and tube formation disruption., PMID:26491858
Functional analysis of candidate genes in 2q13 deletion syndrome implicates FBLN7 and TMEM87B deficiency in congenital heart defects and FBLN7 in craniofacial malformations., PMID:24694933
A C-terminal fragment of fibulin-7 interacts with endothelial cells and inhibits their tube formation in culture., PMID:24480309
Drosophila MMP2 regulates the matrix molecule faulty attraction (Frac) to promote motor axon targeting in Drosophila., PMID:21471368
Anti-Ro/SSA autoantibody-mediated regulation of extracellular matrix fibulins in human epithelial cells of the salivary gland., PMID:19229767
Nerve growth factor promotes differentiation of odontoblast-like cells., PMID:19170059
TM14 is a new member of the fibulin family (fibulin-7) that interacts with extracellular matrix molecules and is active for cell binding., PMID:17699513
For research use only. Not for human or drug use.
