Catalog No.
YHH89701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu309-Lys452
Predicted molecular weight
18.55 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q53H76
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PSPLA1, PS-PLA1, Phosphatidylserine-specific phospholipase A1, PLA1A, NMD, Phospholipase A1 member A
Screening and Identification of Brain Pericyte-Selective Markers., PMID:39912338
Phosphatidylserine phospholipase A1 enables GPR34-dependent immune cell accumulation in the peritoneal cavity., PMID:39412501
Tumor and Peritoneum-Associated Macrophage Gene Signature as a Novel Molecular Biomarker in Gastric Cancer., PMID:38612926
Phospholipase A1 Member A Deficiency Alleviates Mannan-Induced Psoriatic Arthritis in Mice Model., PMID:35955693
Molecular diagnosis of ABMR with or without donor-specific antibody in kidney transplant biopsies: Differences in timing and intensity but similar mechanisms and outcomes., PMID:35575435
Phosphatidylserine-Specific Phospholipase A1 Limits Aggressiveness of Lung Adenocarcinoma by Lysophosphatidylserine and Protein Kinase A-Dependent Pathway., PMID:35358472
A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence., PMID:35220880
Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis., PMID:34884486
Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization., PMID:34089703
PLA1A expression as a diagnostic marker of BRAF-mutant metastasis in melanoma cancer., PMID:33723350
Enhancement of transgene expression by the β-catenin inhibitor iCRT14., PMID:33472046
Higher serum levels of autotaxin and phosphatidylserine-specific phospholipase A1 in patients with lupus nephritis., PMID:33314787
Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma., PMID:32060356
Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism., PMID:31978406
Serum phosphatidylserine-specific phospholipase A1 as a novel biomarker for monitoring systemic lupus erythematosus disease activity., PMID:31468739
Phosphatidylserine-Specific Phospholipase A1 is the Critical Bridge for Hepatitis C Virus Assembly., PMID:31161554
The Spastic Paraplegia-Associated Phospholipase DDHD1 Is a Primary Brain Phosphatidylinositol Lipase., PMID:30221923
PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria., PMID:30016790
Association between serum autotaxin or phosphatidylserine-specific phospholipase A1 levels and melanoma., PMID:29500864
RNA-seq Reveals Transcriptomic Differences in Inflamed and Noninflamed Intestinal Mucosa of Crohn's Disease Patients Compared with Normal Mucosa of Healthy Controls., PMID:28613228
Analysis of glycero-lysophospholipids in gastric cancerous ascites., PMID:28143894
The molecular landscape of antibody-mediated kidney transplant rejection: evidence for NK involvement through CD16a Fc receptors., PMID:25787894
Phosphatidylserine-specific phospholipase A1 involved in hepatitis C virus assembly through NS2 complex formation., PMID:25505071
Expression of bioactive lysophospholipids and processing enzymes in the vitreous from patients with proliferative diabetic retinopathy., PMID:25496321
PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort., PMID:24886443
A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1α in autosomal recessive wooly hair/hypotrichosis., PMID:23768866
Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements., PMID:22904677
The β9 loop domain of PA-PLA1α has a crucial role in autosomal recessive woolly hair/hypotrichosis., PMID:22475755
LPA-producing enzyme PA-PLA₁α regulates hair follicle development by modulating EGFR signalling., PMID:21857648
Expression of phosphatidylserine-specific phospholipase A(1) mRNA in human THP-1-derived macrophages., PMID:20573295
A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A(1) in human serum samples., PMID:20388504
Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis., PMID:20213768
Exploring the specific features of interfacial enzymology based on lipase studies., PMID:16931141
Polymorphisms in the gene encoding phosphatidylserine-specific phospholipase A1 ( PSPLA1)., PMID:12436198
Identification of alterations in gene expression in rat recipients with long-term-surviving cardiac grafts., PMID:12431588
Structure and function of phosphatidylserine-specific phospholipase A1., PMID:12069807
Murine phosphatidylserine-specific phospholipase A1 (Ps-pla1) maps to chromosome 16 but is distinct from the lpd (lipid defect) locus., PMID:11210182
For research use only. Not for human or drug use.
