Catalog No.
YHH58001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp615-Ser735
Predicted molecular weight
15.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q32MZ4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
LRR FLII-interacting protein 1, TRIP, Leucine-rich repeat flightless-interacting protein 1, GCF2, GC-binding factor 2, TAR RNA-interacting protein, LRRFIP1
LRRFIP1 enhances the Wnt/β-catenin pathway by binding to DVLs in myelodysplastic syndrome., PMID:40420163
Analysis of TNS3-203 and LRRFIP1-211 Transcripts as Oral Cancer Biomarkers., PMID:39888120
Genome-wide scan of Flortaucipir PET levels finds JARID2 associated with cerebral tau deposition., PMID:39417126
Chlamydia trachomatis Inc Ct226 is vital for FLI1 and LRRF1 recruitment to the chlamydial inclusion., PMID:39404459
Identification of Nonsynonymous SNPs in Immune-Related Genes Associated with Pneumonia Severity in Pigs., PMID:39202462
Evidence of innate training in bovine γδ T cells following subcutaneous BCG administration., PMID:39100669
The clinical significance and oncogenic function of LRRFIP1 in pancreatic cancer., PMID:38634978
Acute myeloid leukemia with LRRFIP1::FGFR1 rearrangement and a complex karyotype., PMID:37597337
Immune micro-environment analysis and establishment of response prediction model for PD-1 blockade immunotherapy in glioblastoma based on transcriptome deconvolution., PMID:37407848
A multi-omic approach identifies an autism spectrum disorder (ASD) regulatory complex of functional epimutations in placentas from children born preterm., PMID:36938998
ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma., PMID:36780194
CCNB1 and AURKA are critical genes for prostate cancer progression and castration-resistant prostate cancer resistant to vinblastine., PMID:36601001
Identification of diagnostic mRNA biomarkers in whole blood for ankylosing spondylitis using WGCNA and machine learning feature selection., PMID:36172367
Copy number variations of LRRFIP1 gene and the relationship with growth traits in four Chinese sheep., PMID:36170043
LRRFIP1, an epigenetically regulated gene, is a prognostic biomarker and predicts malignant phenotypes of glioma., PMID:35338570
Comparative transcriptome provides insights into the selection adaptation between wild and farmed foxes., PMID:34646484
Global alternative splicing landscape of skeletal muscle atrophy induced by hindlimb unloading., PMID:33987341
Nuclear Factor Kappa-B/Homeobox A9-Mediated Modulation of Leucine-Rich Repeat Flightless-Interacting Protein 1 Is Involved in Advanced Glycation End Product-Induced Endothelial Dysfunction., PMID:33882503
Silencing of LRRFIP1 enhances the sensitivity of gemcitabine in pancreatic cancer cells by activating JNK/c-Jun signaling., PMID:33707114
Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation., PMID:33265962
Rbm24 modulates adult skeletal muscle regeneration via regulation of alternative splicing., PMID:33042276
A novel LRRFIP1-ALK fusion in inflammatory myofibroblastic tumor of hip and response to crizotinib., PMID:32915420
Spliced genes in muscle from Nelore Cattle and their association with carcass and meat quality., PMID:32895448
Integrated Analysis of RNA-Binding Proteins in Glioma., PMID:32272554
Rapalog-Mediated Repression of Tribbles Pseudokinase 3 Regulates Pre-mRNA Splicing., PMID:32245792
MiR-215-5p inhibits the inflammation injury in septic H9c2 by regulating ILF3 and LRRFIP1., PMID:31806569
Duckling short beak and dwarfism syndrome virus infection activates host innate immune response involving both DNA and RNA sensors., PMID:31655218
Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells., PMID:31405957
LRRFIP1 expression triggers platelet agglutination by enhancing αIIbβ3 expression., PMID:31258662
Knockdown of GC binding factor 2 by RNA interference inhibits invasion and migration of vascular smooth muscle cells., PMID:31257544
Multidisciplinary Roles of LRRFIP1/GCF2 in Human Biological Systems and Diseases., PMID:30709060
Recombinant Leucine-Rich Repeat Flightless-Interacting Protein-1 Improves Healing of Acute Wounds through Its Effects on Proliferation Inflammation and Collagen Deposition., PMID:29996558
The alternatively spliced LRRFIP1 Isoform-1 is a key regulator of the Wnt/β-catenin transcription pathway., PMID:28322931
Muscle developmental defects in heterogeneous nuclear Ribonucleoprotein A1 knockout mice., PMID:28077597
SRSF10 Plays a Role in Myoblast Differentiation and Glucose Production via Regulation of Alternative Splicing., PMID:26586428
Silencing of LRRFIP1 reverses the epithelial-mesenchymal transition via inhibition of the Wnt/β-catenin signaling pathway., PMID:26047573
LRRFIP1 Inhibits Hepatitis C Virus Replication by Inducing Type I Interferon in Hepatocytes., PMID:26045710
Integrating phosphoproteome and transcriptome reveals new determinants of macrophage multinucleation., PMID:25532521
Knockdown of GCF2/LRRFIP1 by RNAi causes cell growth inhibition and increased apoptosis in human hepatoma HepG2 cells., PMID:24761896
Higher LRRFIP1 expression in glioblastoma multiforme is associated with better response to teniposide, a type II topoisomerase inhibitor., PMID:24690174
Characterization of Gcf2/Lrrfip1 in experimental cerebral ischemia and its role as a modulator of Akt, mTOR and β-catenin signaling pathways., PMID:24637094
Noncoding RNAs and LRRFIP1 regulate TNF expression., PMID:24567534
The microRNA miR-132 targets Lrrfip1 to block vascular smooth muscle cell proliferation and neointimal hyperplasia., PMID:23880186
Newly described pattern recognition receptors team up against intracellular pathogens., PMID:23846113
Anti-thrombosis effect of LRRFIP1 shRNA lentivirus in a mouse model of deep vein thrombosis., PMID:23751182
One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease., PMID:23557933
A variant in the LRRFIP1 gene is associated with adiposity and inflammation., PMID:23505185
Immunohistochemical analysis of medullary breast carcinoma autoantigens in different histological types of breast carcinomas., PMID:23181716
Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1., PMID:23099021
The lavender plumage colour in Japanese quail is associated with a complex mutation in the region of MLPH that is related to differences in growth, feed consumption and body temperature., PMID:22937744
For research use only. Not for human or drug use.
