Catalog No.
YHH39801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn200
Predicted molecular weight
25.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16878
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cysteine dioxygenase type 1, CDO1, CDO-I, CDO, Cysteine dioxygenase type I
Impact of DNA methylation on the recurrence risk of stage I non-small cell lung cancer with EGFR mutations., PMID:40457471
CDO1 phosphorylation is required for IL-6-induced tumor cell proliferation through governing cysteine availability., PMID:40269955
Circulating Tumor DNA Methylation Is a Biomarker of Poor Recurrence-free Survival in Locally-Advanced Rectal Cancer., PMID:40155013
XDH-1 inactivation causes xanthine stone formation in C. elegans which is inhibited by SULP-4-mediated anion exchange in the excretory cell., PMID:39975063
A proposed role for CDO1 in CNS development: Three children with rare missense variants and a neurological phenotype., PMID:39949058
Metagenomic and Transcriptomic Analysis Reveals Crosstalk Between Intratumor Mycobiome and Hosts in Early-Stage Nonsmoking Lung Adenocarcinoma Patients., PMID:39853685
Bile acid sequestrant inhibits gluconeogenesis via inducing hepatic cysteine dioxygenase type 1 to reduce cysteine availability., PMID:39819116
Hydrogen sulfide mediates the interaction between C. elegans and Actinobacteria from its natural microbial environment., PMID:39786993
Integration of epigenomic and transcriptomic profiling uncovers EZH2 target genes linked to cysteine metabolism in hepatocellular carcinoma., PMID:39516467
Cloning, bioinformatics analysis and expression of the cysteine dioxygenase type 1 (CDO1) gene in domestic yak., PMID:39493813
A Multicenter Cohort Study on DNA Methylation for Endometrial Cancer Detection in Cervical Scrapings., PMID:39487683
Study of the mechanism of fibroblast-like synoviocytes-derived exosomes inducing macrophages M1 polarization and CD8+T cells immune regulation ferroptosis and autophagy in rheumatoid arthritis., PMID:39447763
[Molecular mechanism of CDO1 regulating common metabolic diseases]., PMID:39192790
Ferroptosis-Related Genes in IgA Nephropathy: Screening for Potential Targets of the Mechanism., PMID:39171207
MIR124-3 and NKX6-1 hypermethylation profiles accurately predict metachronous gastric lesions in a Caucasian population., PMID:39169394
LncRNA FAM83H-AS1 inhibits ferroptosis of endometrial cancer by promoting DNMT1-mediated CDO1 promoter hypermethylation., PMID:39159808
Prognostic utility of circulating tumor DNA methylation analysis in stage IV colorectal cancer., PMID:39155651
Analysis of CDO1, PITX2, and CDH13 Gene Methylation in Early Endometrial Cancer for Prediction of Medical Treatment Outcomes., PMID:38732110
lncRNA SNHG4 inhibits ferroptosis by orchestrating miR-150-5p/c-Myb axis in colorectal cancer., PMID:38692535
TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system., PMID:38614226
Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans., PMID:38349720
DNMT3L inhibits hepatocellular carcinoma progression through DNA methylation of CDO1: insights from big data to basic research., PMID:38308276
XJB-5-131 protects chondrocytes from ferroptosis to alleviate osteoarthritis progression via restoring Pebp1 expression., PMID:38304614
H2S-Synthesizing Enzymes Are Putative Determinants in Lung Cancer Management toward Personalized Medicine., PMID:38247476
Cdo1-Camkk2-AMPK axis confers the protective effects of exercise against NAFLD in mice., PMID:38110408
Fathers' preconception smoking and offspring DNA methylation., PMID:37649101
Identification and expression analysis of transcripts involved in taurine biosynthesis during early ontogeny of tropical gar Atractosteus tropicus., PMID:37562582
The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis., PMID:37406020
Hypoxia-inducible factor induces cysteine dioxygenase and promotes cysteine homeostasis in Caenorhabditis elegans., PMID:37205365
UHPLC-Orbitrap-Fusion-TMS-Based Metabolomics Study of Phenylpropionamides in the Seed of Cannabis sativa L. against Alzheimer's Disease., PMID:37072341
Transcriptomic profiles of the ruminal wall in Italian Mediterranean dairy buffaloes fed green forage., PMID:36941576
TP73 Isoform-specific disruption reveals a critical role of TAp73beta in growth suppression and inflammatory response., PMID:36631448
Longitudinal monitoring of cell-free DNA methylation in ALK-positive non-small cell lung cancer patients., PMID:36461127
Development and validation of a novel model for predicting the survival of bladder cancer based on ferroptosis-related genes., PMID:36399105
Identification and validation of ferroptosis-related genes for chronic rhinosinusitis with nasal polyps., PMID:36255469
Cdo1 promotes PPARγ-mediated adipose tissue lipolysis in male mice., PMID:36253617
Adipose tissue cysteine dioxygenase type 1 is associated with an anti-inflammatory profile, impacting on systemic metabolic traits., PMID:36206624
The Cys-N-degron pathway modulates pexophagy through the N-terminal oxidation and arginylation of ACAD10., PMID:36184612
Hepatic Transcriptome Analysis Provides New Insight into the Lipid-Reducing Effect of Dietary Taurine in High-Fat Fed Groupers (Epinephelus coioides)., PMID:35888794
Rumen-protected methionine during heat stress alters mTOR, insulin signaling, and 1-carbon metabolism protein abundance in liver, and whole-blood transsulfuration pathway genes in Holstein cows., PMID:35879168
Hypermethylated CDO1 and ZNF454 in Cytological Specimens as Screening Biomarkers for Endometrial Cancer., PMID:35574348
Methylated DNA markers for plasma detection of ovarian cancer: Discovery, validation, and clinical feasibility., PMID:35370009
Amniotic membrane mesenchymal stem cells-based therapy improves Bmi-1-deficient mandible osteoporosis through stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption., PMID:35319819
Extracellular cystine influences human preadipocyte differentiation and correlates with fat mass in healthy adults., PMID:34519922
Endogenous Taurine Downregulation Is Required for Renal Injury in Salt-Sensitive Hypertensive Rats via CBS/H2S Inhibition., PMID:34484563
Accurate transcriptome assembly by Nanopore RNA sequencing reveals novel functional transcripts in hepatocellular carcinoma., PMID:34255396
Prognostic biomarker identification and tumor classification in breast cancer patients by methylation and transcriptome analysis., PMID:34056873
[Methylation profiles of genes in breast cancer luminal HER2-negative primary tumor during regional lymphnode metastasis]., PMID:33645526
Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis., PMID:33469142
Prediction of Efficacy of Postoperative Chemotherapy by DNA Methylation of CDO1 in Gastric Cancer., PMID:32777557
For research use only. Not for human or drug use.
