Catalog No.
YHH38001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala292-Met640
Predicted molecular weight
41.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16822
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PEPCK-M, PEPCK2, Phosphoenolpyruvate carboxykinase [GTP], mitochondrial, PCK2
Relationship between plasma asprosin, dry matter intake, and plasma glucose at different stages of lactation., PMID:40470287
Melatonin enhances the function of porcine immature Sertoli cells by inhibiting the HMGCS1-estradiol pathway., PMID:40413863
Mathematical modelling of carbohydrate and protein metabolism in muscle., PMID:40409679
Integrated proteomics and phosphoproteomics study reveals the potential tumour suppressive function of PCK2 in hepatocellular carcinoma., PMID:40235441
Plasticity of the mammalian integrated stress response., PMID:40140574
The Expression of Ferroptosis-Related Genes in Hepatocellular Carcinoma and Their Relationships With Prognosis., PMID:40130081
PCK2 promotes invasion and epithelial-to-mesenchymal transition in triple-negative breast cancer by promoting TGF-β/SMAD3 signaling through inhibiting TRIM67-mediated SMAD3 ubiquitination., PMID:40081967
Genetic coupling of enhancer activity and connectivity in gene expression control., PMID:39870618
Insulin Resistance Mediates the Association Between Vitamin D and Non-Alcoholic Fatty Liver Disease., PMID:39867257
FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production., PMID:39821719
Pck2 association with the plasma membrane and efficient response of the cell integrity pathway require regulation of PI4P homeostasis by exomer., PMID:39540318
Lactylation-Driven IGF2BP3-Mediated Serine Metabolism Reprogramming and RNA m6A-Modification Promotes Lenvatinib Resistance in HCC., PMID:39450426
Glycogenesis and glyconeogenesis from glutamine, lactate and glycerol support human macrophage functions., PMID:39424955
Elucidating the effective age for dietary restriction and the key metabolites involved., PMID:39362416
DNA 5mC and RNA m6A Collaborate to Upregulate Phosphoenolpyruvate Carboxykinase 2 for Kupffer Cell Activation., PMID:39337381
Heat Stress Induces Alterations in Gene Expression of Actin Cytoskeleton and Filament of Cellular Components Causing Gut Disruption in Growing-Finishing Pigs., PMID:39272260
Strategy for treating MAFLD: Electroacupuncture alleviates hepatic steatosis and fibrosis by enhancing AMPK mediated glycolipid metabolism and autophagy in T2DM rats., PMID:39261952
Identification of Disease-relevant, Sex-based Proteomic Differences in iPSC-derived Vascular Smooth Muscle., PMID:39211096
Insight in the (Phospho)proteome of Vascular Smooth Muscle Cells Derived From Patients With Abdominal Aortic Aneurysm Reveals Novel Disease Mechanisms., PMID:39206541
Phosphoenolpyruvate carboxykinase 2-mediated metabolism promotes lung tumorigenesis by inhibiting mitochondrial-associated apoptotic cell death., PMID:39193344
Phosphoenolpyruvate carboxykinase-2 (PCK2) is a therapeutic target in triple-negative breast cancer., PMID:39177932
Targeting SOX4/PCK2 signaling suppresses neuroendocrine trans-differentiation of castration-resistant prostate cancer., PMID:39014441
PCK2 maintains intestinal homeostasis and prevents colitis by protecting antibody-secreting cells from oxidative stress., PMID:38934051
Effects of the Interaction between Rumen Microbiota Density-VFAs-Hepatic Gluconeogenesis on the Adaptability of Tibetan Sheep to Plateau., PMID:38928432
Association of mitochondrial phosphoenolpyruvate carboxykinase with prognosis and immune regulation in hepatocellular carcinoma., PMID:38890507
PCK2 induces gefitinib resistance by suppresses ferroptosis in non-small cell lung cancer., PMID:38850814
The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells., PMID:38783087
Tumor-repopulating cells evade ferroptosis via PCK2-dependent phospholipid remodeling., PMID:38720107
Dysregulation of phosphoenolpyruvate carboxykinase in cancers: A comprehensive analysis., PMID:38697449
Electrospun Poly-l-Lactic Acid Membranes Promote M2 Macrophage Polarization by Regulating the PCK2/AMPK/mTOR Signaling Pathway., PMID:38650356
In vitro suppression of porcine epidemic diarrhea virus by Panax notoginseng saponins: assessing antiviral potential., PMID:38565720
Molecular and Biological Characteristics of a Peach Latent Mosaic Viroid PC Isolate in Peach from China: Base Mutations in Hairpin Stems and Implications for Symptomatology., PMID:38522091
Long-stranded non-coding RNAs temporal-specific expression profiles reveal longissimus dorsi muscle development and intramuscular fat deposition in Tianzhu white yak., PMID:38029315
Allosteric regulation of the lid domain of PCK2 as a novel strategy for modulating mitochondrial dynamics., PMID:37885376
Enhanced ileum function in weaned piglets via Laminaria digitata and alginate lyase dietary inclusion: A combined proteomics and metabolomics analysis., PMID:37775079
Thermosensitive hydrogel-based GPR124 delivery strategy for rebuilding blood-spinal cord barrier., PMID:37693060
Integrated analysis of transcriptome and proteome for exploring mechanism of promoting proliferation of equine satellite cells associated with leucine., PMID:37633218
AF9 sustains glycolysis in colorectal cancer via H3K9ac-mediated PCK2 and FBP1 transcription., PMID:37565737
Global gene expression analysis reveals a subtle effect of DEHP in human granulosa cell line HGrC1., PMID:37536456
Sodium butyrate alleviates deoxynivalenol-induced porcine intestinal barrier disruption by promoting mitochondrial homeostasis via PCK2 signaling., PMID:37467604
Effects of Capsaicin on Glucose Uptake and Consumption in Hepatocytes., PMID:37446918
Growth, immunity and transcriptome response to different stocking densities in Litopenaeus vannamei., PMID:37406891
The LncRNA FEZF1-AS1 promotes tumor proliferation in colon cancer by regulating the mitochondrial protein PCK2., PMID:37304670
PCK1 Protects against Mitoribosomal Defects in Diabetic Nephropathy in Mouse Models., PMID:37199399
Chlorpyrifos induced autophagy and mitophagy in common carp livers through AMPK pathway activated by energy metabolism disorder., PMID:37148751
Biallelic pathogenic variants in the mitochondrial form of phosphoenolpyruvate carboxykinase cause peripheral neuropathy., PMID:36845668
Rapid direct conversion of bovine non-adipogenic fibroblasts into adipocyte-like cells by a small-molecule cocktail., PMID:36819108
Association between placental DNA methylation and fetal congenital heart disease., PMID:36396788
Differentially expressed long noncoding RNAs and mRNAs in PC12 cells under lysophosphatidylcholine stimulation., PMID:36369435
Inhibition of IκB Kinase Is a Potential Therapeutic Strategy to Circumvent Resistance to Epidermal Growth Factor Receptor Inhibition in Triple-Negative Breast Cancer Cells., PMID:36358633
For research use only. Not for human or drug use.
