Catalog No.
YHH35101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu135
Predicted molecular weight
17.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16690
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dual specificity protein phosphatase 5, DUSP5, Dual specificity protein phosphatase hVH3, VH3
Design and synthesis of 3,4-seco-lupane triterpene-tryptamine derivatives and revealing their anti-bladder cancer mechanisms by combining TCGA and transcriptomic approaches., PMID:40473811
Load activated FGFR and beta1 integrins target distinct chondrocyte mechano-response genes., PMID:40379111
OTX2 expression contributes progression of gastric cancer in young adults., PMID:40341176
MAP Kinase Phosphatase-5 Deficiency Improves Endurance Exercise Capacity., PMID:40136658
Structural and kinetic characterization of DUSP5 with a Di-phosphorylated tripeptide substrate from the ERK activation loop., PMID:39749114
Gene Expression Profiles in Ovarian Cancer Tissues as a Potential Tool to Predict Platinum-based Chemotherapy Resistance., PMID:39740837
Developing the new diagnostic model by integrating bioinformatics and machine learning for osteoarthritis., PMID:39695788
Mitogen-Activated Protein Kinase Phosphatase-5 is Required for TGF-β Signaling Through a JNK-Dependent Pathway., PMID:39607740
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Glabridin inhibits proliferation and migration in hepatocellular carcinoma by regulating multi-targets., PMID:39510424
Corynoxine exerts the anti-tumor effect on esophageal squamous cell carcinoma principally via the EZH2-DUSP5-ERK1/2-mediated cell growth inhibition., PMID:39383633
Anti-liver cancer therapeutic targets and safety of usenamine A in experimental liver cancer., PMID:39360781
Ethanol enhances selenoprotein P expression via ERK-FoxO3a axis in HepG2 cells., PMID:39345286
Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium., PMID:39283953
Integrated analyses reveal CST7 and DUSP5 regulate Th2 cells differentiation to promote chronic HBV infection., PMID:39237681
DUSP5 deficiency suppresses the progression of acute kidney injury by enhancing autophagy through AMPK/ULK1 pathway., PMID:39218057
BAP1-mediated MAFF deubiquitylation regulates tumor growth and is associated with adverse outcomes in colorectal cancer., PMID:39151323
Proteomic changes of the bovine blood plasma in response to heat stress in a tropically adapted cattle breed., PMID:39149588
PHF10 inhibits gastric epithelium differentiation and induces gastric cancer carcinogenesis., PMID:39127832
Inflammatory gene regulation by Cdc42 in airway epithelial cells., PMID:39067837
[Mechanisms of the Effect of Maternal Age-Related Oocyte Aging on Fertility: Transcriptomic Sequencing Analysis of a Zebrafish Model]., PMID:38948296
ASAH1 facilitates TNBC by DUSP5 suppression-driven activation of MAP kinase pathway and represents a therapeutic vulnerability., PMID:38926346
DUSP5 regulated by YTHDF1-mediated m6A modification promotes epithelial-mesenchymal transition and EGFR-TKI resistance via the TGF-β/Smad signaling pathway in lung adenocarcinoma., PMID:38872157
[Knockdown of dual-specificity phosphatase 5 (DUSP5) inhibits BCG-induced inflammatory response in RAW264.7 macrophages via blocking NF-κB signaling pathway]., PMID:38790096
Epithelial cells derived exosomal miR-203a-3p facilitates stromal inflammation of type IIIA chronic prostatitis/chronic pelvic pain syndrome by targeting DUSP5 and increasing MCP-1 generation., PMID:38724995
LncRNA PART1 Attenuates Myocardial Ischemia-Reperfusion Injury by Regulating TFAP2C/DUSP5 Axis via miR-302a-3p., PMID:38654453
Targeting DUSP5 suppresses malignant phenotypes of BRAF-mutant thyroid cancer cells and improves their response to sorafenib., PMID:38564084
Participation of Long Noncoding RNA FOXP4-AS1 in the Development and Progression of Endometrioid Carcinoma with Epigenetically Silencing DUSP5., PMID:38512300
Impact of knockout of dual-specificity protein phosphatase 5 on structural and mechanical properties of rat middle cerebral arteries: implications for vascular aging., PMID:38200357
Dual-specificity phosphatase 5-mediated fatty acid oxidation promotes Mycobacterium bovis BCG -induced inflammatory responses., PMID:38049081
Identification of lncRNA-based regulatory mechanisms of Takifugu rubripes growth traits in fast and slow-growing family lines., PMID:37976965
Effects of low-level Er:YAG laser irradiation on proliferation and gene expression in primary gingival fibroblasts isolated from mouse maxilla., PMID:37975254
Cold Stress Induces Apoptosis in Silver Pomfret via DUSP-JNK Pathway., PMID:37658990
Enhanced Cerebral Hemodynamics and Cognitive Function Via Knockout of Dual-Specificity Protein Phosphatase 5., PMID:37588944
Functional Mechanism of MicroRNA-25-3p in Hilar Cholangiocarcinoma Cell Proliferation and Migration Through Regulation of Dual Specificity Phosphatase 5., PMID:37394525
Quercetin induces dual specificity phosphatase 5 via serum response factor., PMID:37291053
Host factor DUSP5 potently inhibits dengue virus infection by modulating cytoskeleton rearrangement., PMID:37149044
Variances in the Expression Profile of DUSP1-7 and miRNAs Regulating their Expression in the HaCat Line under LPS and Cyclosporine A., PMID:37032503
MiR-216a-3p inhibits the proliferation and invasion of fibroblast-like synoviocytes by targeting dual-specificity phosphatase 5., PMID:36843205
Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis., PMID:36765305
Evaluation of cellular response to Clostridium difficile toxin-A: a network analysis., PMID:36762215
BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation., PMID:36526622
Dual targeting of aberrant DNA and histone methylation synergistically suppresses tumor cell growth in ATL., PMID:36516085
Circ_0000471 suppresses the progression of ovarian cancer through mediating mir-135b-5p/dusp5 axis., PMID:36369900
DUSP5 and PHLDA1 mutations in mature cystic teratomas of the ovary identified on whole-exome sequencing may explain teratoma characteristics., PMID:36289533
miR-203 suppresses pancreatic cancer cell proliferation and migration by modulating DUSP5 expression., PMID:36183924
Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors., PMID:36105166
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress., PMID:35999210
Screening of genes encoding proteins that interact with ISG15: Probing a cDNA library from a snakehead fish cell line using a yeast two-hybrid system., PMID:35921933
Low concentration triphenyl phosphate fuels proliferation and migration of hepatocellular carcinoma cells., PMID:35776891
For research use only. Not for human or drug use.
