Catalog No.
YHH32701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly154-Arg292
Predicted molecular weight
18.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16635
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EFE2, TAZ, G4.5, Tafazzin, Protein G4.5
E-Cadherin: A conductor of cellular signaling., PMID:40513205
Cytolethal Distending Toxin-increased DNA damage and ploidy involve the YAP/TAZ-TEAD signaling pathway., PMID:40503662
Lats1/2 Are Essential for Developmental Vascular Remodeling and Biomechanical Adaptation to Shear Stress., PMID:40501385
Molecular patterns and mechanisms of tumorigenesis in HPV-associated and HPV-independent sinonasal squamous cell carcinoma., PMID:40500270
YAP, TAZ, and Hippo-Dysregulating Fusion Proteins in Cancer., PMID:40491864
Biopolymer hydrogels in biomedicine: Bridging chemistry, biology, and clinical translation., PMID:40490181
Crosstalk between MST1-Hippo and Wnt/β-Catenin, Notch, and PI3K/Akt pathways in cardiac physiology and pathology., PMID:40489018
Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation., PMID:40488107
Atypical Hippo signaling network: uncovering novel insights into head and neck cancer biology and advancements in precision intervention., PMID:40486910
TEADlight, a bright dynamic reporter for live detection of YAP/TAZ-TEAD signaling., PMID:40482695
Proteomic landscape of decellularized breast carcinomas identifies C-type lectin domain family 3 member A as a driver of cancer aggressiveness., PMID:40480997
The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2., PMID:40478800
Vitamin D promotes wound healing in aged skin by modulating inflammation, angiogenesis, and EMT via the Hippo pathway., PMID:40466431
Nanoscale Curvature Regulates YAP/TAZ Nuclear Localization Through Nuclear Deformation and Rupture., PMID:40462347
PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in mice., PMID:40454481
Transcription Factors and Coregulators in Schwann Cell Differentiation, Myelination, and Remyelination: Implications for Peripheral Neuropathy., PMID:40452391
Genetic compensation response contributes to Pleurodeles waltl limb regeneration., PMID:40450023
Molecular basis and therapeutic implications of binary YAPOn/YAPOff cancer classes., PMID:40440076
Therapeutic efficacy of canagliflozin against hepatocarcinogenesis induced by CDD/DEN/TAA in a rat model: regulation of AMPK/HIF-1α/YAP-1/TAZ signaling pathways., PMID:40439888
ITIH4 attenuates acute lung injury by Fe-containing particulate matter in mice via Hippo pathway in type II alveolar epithelial cells., PMID:40437524
CD71-Mediated Effects of Soluble Vasorin on Tumor Progression, Angiogenesis and Immunosuppression., PMID:40430053
The IL-18 receptor is expressed on murine small-intestinal enterochromaffin cells and executes a recovery program upon injury., PMID:40424129
Local C1q/TNF-related protein 1 attenuates kidney inflammation and fibrosis by regulating macrophage activation., PMID:40424084
WIPF1 regulates stemness in small cell lung cancer., PMID:40415347
Mechanisms underlying obesity-malignancy connection: a systematic narrative review., PMID:40408050
Double-sided niche regulation in skin stem cell and cancer: mechanisms and clinical applications., PMID:40399946
JAM-C prevents ocular fibrosis by suppressing the TAZ/KLF6 pathway., PMID:40398745
Swimming induces bone loss via regulating mechanical sensing pathways in bone marrow., PMID:40395774
Restoring Prostacyclin/PGI2-PTGIR signaling alleviates intestinal fibrosis in Crohn's disease via fibroblast-specific YAP/TAZ inhibition., PMID:40390655
Activation of Hippo/YAP signaling pathway exacerbates vascular remodeling and aggravates hypertension by upregulating Foxm1., PMID:40388085
YAP/TAZ: An epitome of tumorigenesis., PMID:40381686
A spreadable self-gelling hemostatic powder sensitizes CAR-NK cell therapy to prevent hepatocellular carcinoma recurrence postresection., PMID:40380326
ABHD18 degrades cardiolipin by stepwise hydrolysis of fatty acids., PMID:40378955
Auranofin resensitizes ferroptosis-resistant lung cancer cells to ferroptosis inducers., PMID:40373379
LPAR6 Inhibits the Progression of Hepatocellular Carcinoma (HCC) by Suppressing the Nuclear Translocation of YAP/TAZ., PMID:40362442
Targeting the Hippo Pathway in Breast Cancer: A Proteomic Analysis of Yes-Associated Protein Inhibition., PMID:40362184
[Mechanism of icariin in promoting osteogenic differentiation of BMSCs and improving bone metabolism disorders through caveolin-1/Hippo signaling pathway]., PMID:40350837
Tuina promotes nerve myelin regeneration in SNI rats through Piezo1/YAP/TAZ pathway., PMID:40350445
The Patatin-Like Phospholipase Domain-Containing 3 148M Variant Exacerbates Alcohol-Induced Liver Injury and Tumorigenesis in Mice., PMID:40350061
Matrix Softness Induces an Afibrogenic Lipofibroblast Phenotype in Fibroblasts from IPF Patients., PMID:40343813
VGLL2 and TEAD1 fusion proteins identified in human sarcoma drive YAP/TAZ-independent tumorigenesis by engaging EP300., PMID:40338073
YAP/TAZ activity in PDGFRα-expressing alveolar fibroblasts modulates AT2 proliferation through Wnt4., PMID:40333185
A murine model of Barth syndrome recapitulates human cardiac and skeletal muscle phenotypes., PMID:40326536
Wogonin potentiates the irradiation effect on hepatocellular carcinoma by activating the Hippo-Yes-associated protein/transcriptional co-activator with PDZ-binding motif pathway., PMID:40318272
Calcaratarin D, a labdane diterpenoid, attenuates bleomycin-induced pulmonary fibrosis by blocking Wnt/β-catenin signaling pathway., PMID:40311955
The cardiac glycoside periplocymarin sensitizes gastric cancer to ferroptosis via the ATP1A1-Src-YAP/TAZ-TFRC axis., PMID:40311597
Vestigial-like family member 1 (VGLL1): An emerging candidate in tumor progression., PMID:40300335
Down-regulation of YAP prevents smoking- and alcohol-induced carcinogenesis of esophageal paracancerous tissue by promoting cellular pyroptosis., PMID:40295580
Expression of YAP1 and TAZ in Melanoma-, Bronchial- and Breast Carcinoma Brain Metastasis: Primary vs. Relapsed Tumors., PMID:40295045
The Hippo pathway in bone and cartilage: implications for development and disease., PMID:40292098