Catalog No.
YHH32101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys266-Thr522
Predicted molecular weight
32.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16625
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Occludin, OCLN
Artemether Improves Aβ1-42-Induced Mitochondrial Dysfunction and Protects Against Blood-Brain Barrier Damage Through Activating the CAMKK2/AMPK/PGC1α Signaling Pathway., PMID:40493345
Transcriptional characterization of sepsis in a LPS porcine model., PMID:40471388
Profiling Tight Junction Protein Expression in Brain Vascular Malformations., PMID:40429705
The effect of anthocyanin extract from Lycium ruthenicum Murray on intestinal barrier function in Bamei ternary pigs., PMID:40410595
Regulation of IL-1β gene expression and its function of defense mechanism in rumen epithelial cells from pre- and postweaning calves., PMID:40400194
Dietary supplementation with antibacterial peptide microcin J25 improved antioxidant capacity and intestinal health of pigeons., PMID:40351762
LncRNA NEAT1 protects uremic toxin-induced intestinal epithelial barrier injury by regulating miR-122-5p/Occludin axis., PMID:40338929
Exogenous acetate mitigates later enhanced allergic airway inflammation in a menopausal mouse model., PMID:40292217
EGF-Induced Macropinocytosis Promotes NAV1-Dependent Internalization of Occludin in Keratinocytes., PMID:40266031
Exposure of broiler chickens to deoxynivalenol and Campylobacter jejuni induces substantial changes in intestinal gene expression., PMID:40253521
Mesenchymal Stem Cells Restore Endothelial Integrity and Alleviate Emotional Impairments in a Diabetic Mouse Model via Inhibition of MMP-9 Activity., PMID:40244194
ALKBH5 Improves the Epithelial Cell Tight Junctions to Inhibit Escherichia coli-Induced Mastitis., PMID:40214476
Reduced occludin expression is related to unfavorable tumor phenotype and poor prognosis in many different tumor types: A tissue microarray study on 16,870 tumors., PMID:40173205
PVA and PVP nanofibers combined with Helichrysum italicum oil preserve skin cell interactions, elasticity and proliferation., PMID:40158043
Bifidobacterium breve HH079 alleviates early-life antibiotic-exposed colon dysbiosis in mice by restoring the gut microbiota and gut barrier function., PMID:40143684
Repetitive Low-Level Blast Exposure Alters Circulating Myeloperoxidase, Matrix Metalloproteinases, and Neurovascular Endothelial Molecules in Experienced Military Breachers., PMID:40076437
Growth patterns and heat tolerance analysis of dwarf chicken with frizzled feather., PMID:40073636
Long-term consumption of moderate amounts of sucrose-sweetened drinks disrupts intestinal barrier function by impairing goblet cell differentiation., PMID:40072586
Farnesoid X receptor induction decreases invasion and tumor progression by JAK2/occludin signaling in human glioblastoma cells., PMID:40058449
Modulation of occludin, NF-κB, p-STAT3, and Th17 response by DJ-X-025 decreases inflammation and ameliorates experimental colitis., PMID:40036995
Claudin-1 impairs blood-brain barrier by downregulating endothelial junctional proteins in traumatic brain injury., PMID:40018968
Mechanisms of the effects of turpiniae folium extract on growth performance, immunity, antioxidant activity and intestinal barrier function in LPS-challenged broilers., PMID:39985896
Dolutegravir induces endoplasmic reticulum stress at the blood-brain barrier., PMID:39985305
Estrogen prevented gingival barrier injury from Porphyromonas gingivalis lipopolysaccharide., PMID:39976433
Hydroxy-selenomethionine helps cows to overcome heat stress by enhancing antioxidant capacity and alleviating blood-milk barrier damage., PMID:39967694
Bifidobacterium bifidum CCFM1163 alleviates cathartic colon by activating the BDNF-TrkB-PLC/IP3 pathway to reconstruct the intestinal nerve and barrier., PMID:39963068
Investigation of the nutritional and functional roles of a microencapsulated blend of botanicals on intestinal health and growth of nursery pigs challenged with F18+Escherichia coli., PMID:39953722
Rosuvastatin mitigates blood-brain barrier disruption in sepsis-associated encephalopathy by restoring occludin levels., PMID:39953583
Benzyl butyl phthalate promotes ferroptosis in Sertoli cells via disrupting ceruloplasmin-mediated iron balance., PMID:39921026
Real-world of Limosilactobacillus reuteri in mitigation of acute experimental colitis., PMID:39891249
Effects of Production System With or Without Growth-Promoting Technologies on Growth and Blood Expression of (Cyto)Chemokines and Heat Shock and Tight Junction Proteins in Bos taurus and indicus Breeds During Summer Season., PMID:39852940
RhoA/ROCK2 signaling pathway regulates Mn-induced alterations in tight junction proteins leading to cognitive dysfunction in mice., PMID:39834519
The protein ingredient quality of infant formula influences colonic physiology and microbiota and the serum metabolomic profile in neonatal mini-piglets., PMID:39779144
Anti-inflammatory, anti-colitis, and antioxidant effects of columbianadin against DSS-induced ulcerative colitis in rats via alteration of HO-1/Nrf2 and TLR4-NF-κB signaling pathway., PMID:39757276
Impact of the probiotic Bacillus coagulans on loperamide-induced delayed bowel movement in Sprague-Dawley rats., PMID:39745362
Annexin A1 Mitigates Blood-Brain Barrier Disruption in a Sepsis-Associated Encephalopathy Model by Enhancing the Expression of Occludin and Zonula Occludens-1 (ZO-1)., PMID:39727329
Expression of PRAME in high-grade serous carcinoma is associated with higher residual disease volume and Occludin expression., PMID:39709875
Tirzepatide, a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), positively impacts the altered microbiota of obese, diabetic, ovariectomized mice., PMID:39675551
Effects of deoxynivalenol contaminated corn distiller's dried grains with solubles on growth performance, body composition, immunological response, and gastrointestinal health in young pullets., PMID:39675103
Crocin nano-chitosan-coated compound mitigates hippocampal blood-brain barrier disruption, anxiety, and cognitive deficits in chronic immobilization stress-induced rats., PMID:39640648
INTESTINAL EPITHELIAL-SPECIFIC OCCLUDIN DELETION WORSENS GUT PERMEABILITY AND SURVIVAL FOLLOWING SEPSIS., PMID:39637366
HSP105 inhibition downregulates store-operated calcium entry and promotes acute UVB-induced tight junction disruption., PMID:39637147
AD-Like Neuropsychiatric Dysfunction in a Mice Model Induced by a Combination of High-Fat Diet and Intraperitoneal Injection of Streptozotocin., PMID:39626951
Circulating Blood-Brain Barrier Proteins for Differentiating Ischaemic Stroke Patients from Stroke Mimics., PMID:39595521
Threonine attenuates lipopolysaccharide-induced intestinal inflammatory responses in rabbits., PMID:39549129
Comparative evaluation of the modulatory role of 1,25-dihydroxy-vitamin D3 on endoplasmic reticulum stress-induced effects in 2D and 3D cultures of the intestinal porcine epithelial cell line IPEC-J2., PMID:39521992
Occludin Is Essential to Maintain Normal Alveolar Barrier Integrity and Its Protective Role During ARDS Progression., PMID:39519146
Dietary Zanthoxylum bungeanum leaf powder improves growth performance and antioxidant capacity via Nrf2/HO-1 signaling pathway in broilers., PMID:39513326
Claudin-5 and occludin levels in patients with psychiatric disorders - A systematic review., PMID:39500414
Exploration of age-related changes in reproductive parameters of female Japanese quail (Coturnix japonica)., PMID:39500266