Catalog No.
YHH31001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu23-Glu133
Predicted molecular weight
13.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16602
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CGRP type 1 receptor, CGRPR, Calcitonin receptor-like receptor, CALCRL, Calcitonin gene-related peptide type 1 receptor
CALCR interaction with ANTXR1 drives gastric tumor growth and metastasis via AKT signaling pathway., PMID:40195530
Upregulation of the neuropeptide receptor calcitonin receptor-like in the spinal cord via MLL2 in a mouse model of paclitaxel-induced peripheral neuropathy., PMID:39905828
Neuropeptide signalling orchestrates T cell differentiation., PMID:39415015
Differential expression of components of the CGRP-receptor family in human coronary and human middle meningeal arteries: functional implications., PMID:39390360
Extracellular bimolecular fluorescence complementation for investigating membrane protein dimerization: a proof of concept using class B GPCRs., PMID:39361899
Overexpression of CGRP receptor attenuates tendon graft degeneration in anterior cruciate ligament reconstruction., PMID:39318262
A cheminformatics and network pharmacology approach to elucidate the mechanism of action of Mycobacterium tuberculosis γ-carbonic anhydrase inhibitors., PMID:39286631
CALCR exacerbates renal cell carcinoma progression via stabilizing CD44., PMID:38985127
Fine mapping of candidate effector genes for heart rate., PMID:38969939
Quantitative proteomics reveals CLR interactome in primary human cells., PMID:38777147
Innervation of nociceptor neurons in the spleen promotes germinal center responses and humoral immunity., PMID:38772371
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro., PMID:38602103
Activation of CGRP receptor-mediated signaling promotes tendon-bone healing., PMID:38457499
CALCRL knockdown suppresses cancer stemness and chemoresistance in acute myeloid leukemia with FLT3-ITD and DNM3TA-R882 double mutations., PMID:38349260
Distinctive genes and signaling pathways associated with type 2 diabetes-related periodontitis: Preliminary study., PMID:38241313
CALCRL induces resistance to daunorubicin in acute myeloid leukemia cells through upregulation of XRCC5/TYK2/JAK1 pathway., PMID:37948318
Antinociceptive effect of the calcitonin gene-related peptide receptor antagonist BIBN4096BS in mice with bacterial cystitis., PMID:37823199
Calcitonin Related Polypeptide Alpha Mediates Oral Cancer Pain., PMID:37443709
Reassessing the adrenomedullin scavenging function of ACKR3 in lymphatic endothelial cells., PMID:37252916
Galectin-1 Regulates RNA Expression and Alternative Splicing of Angiogenic Genes in HUVECs., PMID:37114537
Uterine histotroph and conceptus development: III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway., PMID:37036518
Expression of the Calcitonin Receptor-like Receptor (CALCRL) in Normal and Neoplastic Tissues., PMID:36835377
Identification of a Five Immune Term Signature for Prognosis and Therapy Options (Immunotherapy versus Targeted Therapy) for Patients with Hepatocellular Carcinoma., PMID:36785674
Response to erenumab assessed by Headache Impact Test-6 is modulated by genetic factors and arterial hypertension: An explorative cohort study., PMID:36627267
Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth., PMID:36374225
Inhibition of CGRP signaling impairs fracture healing in mice., PMID:36281531
Plasma Clearance of Intravenously Infused Adrenomedullin in Rats with Acute Renal Failure., PMID:36139120
Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance., PMID:36081671
Identification of Hub Genes of Lung Adenocarcinoma Based on Weighted Gene Co-Expression Network in Chinese Population., PMID:36032660
The Analysis of a Genome-Wide Association Study (GWAS) of Overweight and Obesity in Psoriasis., PMID:35806402
Identification of Novel Genes for Cell Fusion during Osteoclast Formation., PMID:35742859
A Single Injection of NTG-101 Reduces the Expression of Pain-Related Neurotrophins in a Canine Model of Degenerative Disc Disease., PMID:35628530
The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling., PMID:35563897
CALCRL Gene is a Suitable Prognostic Factor in AML/ETO+ AML Patients., PMID:35342399
Identification of Synovial Fibroblast-Associated Neuropeptide Genes and m6A Factors in Rheumatoid Arthritis Using Single-Cell Analysis and Machine Learning., PMID:35186167
Identification and validation of CALCRL-associated prognostic genes in acute myeloid leukemia., PMID:34655717
Calcitonin receptor-like (CALCRL) is a marker of stemness and an independent predictor of outcome in pediatric AML., PMID:34559198
Sensory nerves: A driver of the vicious cycle in bone metastasis?, PMID:34504741
CALCR knockdown inhibits the development and progression of non-small-cell lung cancer., PMID:34417812
Role of CGRP pathway polymorphisms in migraine: a systematic review and impact on CGRP mAbs migraine therapy., PMID:34330208
In-depth bioinformatic study of the cadherin 5 interactome in patients with thoracic aortic aneurysm unveils 8 novel biomarkers., PMID:34293135
Temporal and spatial expression of adrenomedullin and its receptors in the porcine uterus and peri-implantation conceptuses., PMID:34104954
Identification of significant genes as prognostic markers and potential tumor suppressors in lung adenocarcinoma via bioinformatical analysis., PMID:34039311
Gene expression changes contribute to stemness and therapy resistance of relapsed acute myeloid leukemia: roles of SOCS2, CALCRL, MTSS1, and KDM6A., PMID:34029637
A genetic map of the mouse dorsal vagal complex and its role in obesity., PMID:33767443
Adrenomedullin 2 and 5 activate the calcitonin receptor-like receptor (clr) - Receptor activity-modifying protein 3 (ramp3) receptor complex in Xenopus tropicalis., PMID:33711314
Structure and dynamics of the CGRP receptor in apo and peptide-bound forms., PMID:33602864
Role of calcitonin gene-related peptide in pain regulation in the parabrachial nucleus of naive rats and rats with neuropathic pain., PMID:33524449
Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells., PMID:33462236
Development of a prognostic model of glioma based on immune-related genes., PMID:33376548
For research use only. Not for human or drug use.
