Catalog No.
YHH25201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly130-Ala280
Predicted molecular weight
18.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16270
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Prostacyclin-stimulating factor, IGFBP7, MAC25, MAC25 protein, IGFBP-rP1, Tumor-derived adhesion factor, TAF, PSF, IGF-binding protein 7, IGFBP-7, IBP-7, PGI2-stimulating factor, Insulin-like growth factor-binding protein 7
Machine learning algorithms integrate bulk and single-cell RNA data to reveal the crosstalk and heterogeneity of NOTCH and autophagy activity following idiopathic pulmonary fibrosis., PMID:40494203
IGFBP7 inhibition relieves LPS induced nucleus pulposus cell injury by regulating the ERK1/2 pathway., PMID:40488211
Proteomic and Genetic predictors and risk scores of cardiovascular diseases in persons living with HIV., PMID:40463557
ST2, CLSTN2, IGFBP-7 and GDNF proteins gene expressions are associated with presence of carotid plaques in the general population independently from classical risk factors: A cross-sectional study., PMID:40445178
Age-related stress gene expression in neonatal sepsis involves regulatory networks and immune cell infiltration., PMID:40442112
Urinary NGAL Outperforms 99mTc-MAG3 Renography in Predicting DCD Kidney Graft Function., PMID:40421388
The Association between Serially Measured Circulating Biomarker Patterns and Pulmonary Artery Pressures measured by Invasive Hemodynamic Monitoring., PMID:40414277
Postoperative acute kidney injury in major abdominal surgery. Utility of the urinary biomarker [TIMP-2] × [IGFBP7] (NephroCheck™)., PMID:40409484
IGFBP7: A novel biomarker involved in a positive feedback loop with TGF-β1 in idiopathic pulmonary fibrosis., PMID:40381971
Prognostic and diagnostic value of PVR gene and protein levels, serum amylase, and urinary IGFBP-7 and TIMP-2 biomarkers in multiple myeloma., PMID:40369504
Investigation of the Pathogenesis of Liver Fibrosis Associated with Type 2 Diabetes Mellitus via Bioinformatic Analysis., PMID:40299397
Urine TIMP2.IGFBP7 Reflects Kidney Injury After Moderate Volume Paracentesis in Patients With Ascites: A Randomized Control Study., PMID:40264987
Does combining urine sediment examination to renal cell arrest and damage biomarkers improve prediction of progression and mortality of sepsis associated acute kidney injury?, PMID:40247231
Proteomic signatures for fibrosis in MASLD: a biopsy-proven dual-cohort study., PMID:40237197
Biomarker and cognitive decline in atrial fibrillation: a prospective cohort study., PMID:40234472
Genetic determinants and clinical significance of circulating and tumor-specific levels of insulin-like growth factor binding protein 7 (IGFBP7) in a Swedish breast cancer cohort., PMID:40230015
Identification of Ferroptosis-Associated Genes in Primary Open-Angle Glaucoma through Bioinformatics Analysis., PMID:40228223
Comparison and Analysis of the Drug-Resistance Mechanism of Osimertinib- and Almonertinib-Resistant Cell Lines., PMID:40224214
Urinary [TIMP-2]•[IGFBP7], TIMP-2, IGFBP7, NGAL, and L-FABP for the prediction of acute kidney injury following cardiovascular surgery in Japanese patients., PMID:40195176
Plasma Insulin-like Growth Factor-Binding Protein-7 Is Positively Associated with Age, Obesity, Mortality, and Cancer in Postmenopausal Women., PMID:40152978
Biomarkers of cell cycle arrest, microcirculation dysfunction, and inflammation in the prediction of SA-AKI., PMID:40055460
The effects of urine alkalinization on kidney function in critically ill patients with COVID-19: a proof-of-concept randomized clinical trial., PMID:40055234
Advances in the diagnosis of early biomarkers for acute kidney injury: a literature review., PMID:40045274
Enteric GABAergic neuron-derived γ-aminobutyric acid initiates expression of Igfbp7 to sustain ILC3 homeostasis., PMID:40033120
Effects of Oral Administration of the Probiotic Lactobacillus rhamnosus GG on the Proteomic Profiles of Cerebrospinal Fluid and Immunoregulatory Signaling in the Hippocampus of Adult Male Rats., PMID:40031897
Evaluation of uNGAL and TIMP-2*IGFBP7 as early biomarkers of Acute Kidney Injury in Caucasian term and preterm neonates: a prospective observational cohort study., PMID:40025594
Insulin like growth factor binding protein 7 activate JNK/ERK signaling to aggravate uranium-induced renal cell cytotoxicity., PMID:40021513
Vitamin C Mediates IGFBP7 to Alleviate Chronic Atrophic Gastritis via the HIF-1α/VEGF Pathway., PMID:40012220
Elevated IGFBP7 expression in follicular granulosa cells promotes PCOS pathogenesis., PMID:39988179
Efficacy of urinary [TIMP-2]⋅[IGFBP7], L-FABP, and NGAL levels for predicting community-acquired acute kidney injury in Japanese patients: a single-center, prospective cohort study., PMID:39982587
Association between Insulin-Like Growth Factor Binding Protein-7 and Heart Failure., PMID:39950473
Interleukin-38 as a potential diagnostic biomarker for heart failure., PMID:39949181
The efficacy of novel biomarkers for the early detection and management of acute kidney injury: A systematic review., PMID:39879206
Protective effect of Panax ginseng extract on cisplatin-induced AKI via downregulating cell death associated genes., PMID:39863673
Influence of work intensity on acute kidney injury risk during simulated occupational heat stress., PMID:39855252
Urinary biomarkers for diagnosing acute kidney injury in sepsis in the emergency department., PMID:39811377
CD93 blockade promotes effector T-cell infiltration and facilitates adoptive cell therapy in solid tumors., PMID:39805660
NephroCheck as a Predictor of Acute Kidney Injury Following Coronary Artery Bypass Graft Surgery., PMID:39803121
Artificial Intelligence-Guided Identification of IGFBP7 as a Critical Indicator in Lactic Metabolism Determines Immunotherapy Response in Stomach Adenocarcinoma., PMID:39788916
Exploring the link: DNA methylation and kidney injury markers in farmers exposed to glyphosate-surfactant herbicides., PMID:39701272
Proteomic Alterations in Retinal Müller Glial Cells Lacking Interleukin-6 Receptor: A Comprehensive Analysis., PMID:39699914
Delayed Administration of IGFBP7 Improved Bone Defect Healing via ZO-1 Dependent Vessel Stabilization., PMID:39698844
Insulin-like growth factor binding protein 7 identified in aged dental pulp by single-cell RNA sequencing., PMID:39674503
Serum protein risk stratification score for diagnostic evaluation of metabolic dysfunction-associated steatohepatitis., PMID:39621304
Meta-analysis of proteomics data from osteoblasts, bone, and blood: Insights into druggable targets, active factors, and potential biomarkers for bone biomaterial design., PMID:39620099
Immuno-PET Imaging of CD93 Expression with 64Cu-Radiolabeled NOTA-mCD93 ([64Cu]Cu-NOTA-mCD93) and Insulin-Like Growth Factor Binding Protein 7 ([64Cu]Cu-NOTA-IGFBP7)., PMID:39533706
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways., PMID:39533382
Causal associations between the insulin-like growth factor family and sarcopenia: a bidirectional Mendelian randomization study., PMID:39507055
Single-Cell Meta-Analysis Uncovers the Pancreatic Endothelial Cell Transcriptomic Signature and Reveals a Key Role for NKX2-3 in PLVAP Expression., PMID:39445426
Gastrointestinal permeability and kidney injury risk during hyperthermia in young and older adults., PMID:39417775
For research use only. Not for human or drug use.
