Catalog No.
YHH24101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala12-Pro182
Predicted molecular weight
21.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q16082
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DMPK-binding protein, HSPB2, HspB2, MKBP, Heat shock protein beta-2
Decreased Expression of Alzheimer's Disease-Related Genes in Cancer May Contribute to the Inverse-Relationship-a Computational Study., PMID:40352571
Comprehensive analysis of heat shock proteins in glioma revealed the association with glioma-associated myeloid cells., PMID:40234584
Dihydromyricetin protects against cisplatin-induced renal injury and mitochondria-mediated apoptosis via the EGFR/HSP27/STAT3 signaling pathway., PMID:40230054
Heat shock protein 27 downregulation attenuates isoprenaline-induced myocardial fibrosis and diastolic dysfunction by modulating the endothelial-mesenchymal transition., PMID:39515591
One day of environment-induced heat stress damages the murine myocardium., PMID:39212770
Compartmentalization proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation., PMID:38827406
Significant genomic introgression from grey junglefowl (Gallus sonneratii) to domestic chickens (Gallus gallus domesticus)., PMID:38556896
Rapamycin protects mouse skin from ultraviolet B-induced photodamage by modulating Hspb2-mediated autophagy and apoptosis., PMID:38183537
HSP27 induced glaucomatous damage in mice of young and advanced age., PMID:37744880
HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury., PMID:37606039
CD93 Ameliorates Diabetic Wounds by Promoting Angiogenesis via the p38MAPK/MK2/HSP27 Axis., PMID:37295599
Dynamics and Composition of Small Heat Shock Protein Condensates and Aggregates., PMID:37146746
Evaluation of the Small Heat Shock Protein Family Members HSPB2 and HSPB3 in Bladder Cancer Prognosis and Progression., PMID:36768927
Sex-Specific Genetic and Transcriptomic Liability to Neuroticism., PMID:36244801
High mRNA Expression Levels of Heat Shock Protein Family B Member 2 (HSPB2) Are Associated with Breast Cancer Patients' Relapse and Poor Survival., PMID:36077156
Exploitation of High Tumour GSH Levels for Targeted siRNA Delivery in Rhabdomyosarcoma Cells., PMID:36009022
Machine learning-based screening of the diagnostic genes and their relationship with immune-cell infiltration in patients with lung adenocarcinoma., PMID:35399247
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice., PMID:35146957
αB-crystallin/HSPB2 is critical for hyperactive mTOR-induced cardiomyopathy., PMID:34101831
Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein., PMID:34046506
Quantitative Proteomics Analysis for the Identification of Differential Protein Expression in Calf Muscles between Young and Old SD Rats Using Mass Spectrometry., PMID:33778255
Increased IGFBP7 Expression Correlates with Poor Prognosis and Immune Infiltration in Gastric Cancer., PMID:33531979
Differential Effects of Homologous Transcriptional Regulators NicR2A, NicR2B1, and NicR2B2 and Endogenous Ectopic Strong Promoters on Nicotine Metabolism in Pseudomonas sp. Strain JY-Q., PMID:33187996
Mog1 knockout causes cardiac hypertrophy and heart failure by downregulating tbx5-cryab-hspb2 signalling in zebrafish., PMID:33032360
Unlike estrogens that increase PCSK9 levels post-menopause HSP27 vaccination lowers cholesterol levels and atherogenesis due to divergent effects on PCSK9 and LDLR., PMID:33022407
Heme induces rapid endothelial barrier dysfunction via the MKK3/p38MAPK axis., PMID:32548640
Exercise modulates heat shock protein 27 activity in diabetic cardiomyopathy., PMID:31904365
Molecular chaperone HspB2 inhibited pancreatic cancer cell proliferation via activating p53 downstream gene RPRM, BAI1, and TSAP6., PMID:31692031
Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline., PMID:31479860
Cognition may link cortical IGFBP5 levels with motor function in older adults., PMID:31404102
Simultaneous use of natural adjuvants and cell penetrating peptides improves HCV NS3 antigen-specific immune responses., PMID:31254535
The Hsp27-Mediated IkBα-NFκB Signaling Axis Promotes Radiation-Induced Lung Fibrosis., PMID:31126962
Novel predictive epigenetic signature for temozolomide in non-G-CIMP glioblastomas., PMID:31088577
Adverse Effects in Skeletal Muscle Following the Medicinal Use of Nicotiana glauca., PMID:31061309
Iron Oxide Nanoparticles Affects Behaviour and Monoamine Levels in Mice., PMID:30941547
Correlation of clinical symptoms and signs with conjunctival gene expression in primary Sjögren syndrome dry eye patients., PMID:30905840
Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons., PMID:30875674
Binge ethanol and MDMA combination exacerbates HSP27 and Trx-1 (biomarkers of toxic cardiac effects) expression in right ventricle., PMID:30708098
Modulation of Heat Shock Response Proteins by ASS234, Targeted for Neurodegenerative Diseases Therapy., PMID:30133257
Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3., PMID:29969581
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia., PMID:29908079
Molecular mechanism for the influence of gender dimorphism on alcoholic liver injury in mice., PMID:29792338
HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis., PMID:29650953
HSP27 inhibitor attenuates radiation-induced pulmonary inflammation., PMID:29520071
The small heat shock proteins, especially HspB4 and HspB5 are promising protectants in neurodegenerative diseases., PMID:29425965
Methamphetamine withdrawal induces activation of CRF neurons in the brain stress system in parallel with an increased activity of cardiac sympathetic pathways., PMID:29383398
Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation., PMID:29363670
LPS ameliorates renal ischemia/reperfusion injury via Hsp27 up-regulation., PMID:29124510
Evolutionary Origins of Pax6 Control of Crystallin Genes., PMID:28903537
Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function., PMID:28854361
For research use only. Not for human or drug use.
