Catalog No.
YHH20101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp259-Ser462
Predicted molecular weight
25.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15797
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BSP1, Mothers against DPP homolog 1, Mothers against decapentaplegic homolog 1, SMAD1, Transforming growth factor-beta-signaling protein 1, MADH1, JV4-1, MADR1, SMAD family member 1, hSMAD1, SMAD 1, MAD homolog 1, Mad-related protein 1, BSP-1, Smad1
Exosomal BMPR2 Macromolecule Facilitates Alveolar Epithelial Cell Repair Through Functional Complex Formation with BMPR1B in Acute Lung Injury., PMID:40502982
Identification of amh and its potential signaling pathway involved in the ovary development in the Largemouth Bass (Micropterus salmoides)., PMID:40499662
Gold-doped wollastonite nanohybrids enhance bone regeneration via the bone morphogenetic protein-2, SMAD1, and Runt-related transcription factor-2 signalling pathway., PMID:40487310
Distinct BMP-smad signaling outputs confer diverse functions in dental mesenchyme., PMID:40446216
Regulatory Roles of E3 Ubiquitin Ligases and Deubiquitinases in Bone., PMID:40427572
Tilorone attenuates high-fat diet-induced hepatic steatosis by enhancing BMP9-Smad1/5/8 signaling., PMID:40423936
Compressive Force Inhibits Osteogenic Differentiation of Dental Follicle Stem Cells Through Biglycan/Bone Morphogenetic Protein2/Smad1 Signaling Pathway., PMID:40395190
Harnessing the potential of recombinant human BMP2: regulating scleral changes in myopic guinea pigs., PMID:40375931
Gestational Exposure to Phenanthrene Induces Superfluous Fibrosis and Calcification and Metabolic Imbalance of the Placenta in Mice., PMID:40359265
Anti-Müllerian hormone signalling sustains circadian homeostasis in zebrafish., PMID:40348785
Ishophloroglucin A Isolated From Ishige okamurae Stimulates Osteoblast Differentiation Through Activation of the Bone Morphogenetic Protein and Wnt/β-Catenin Signaling Pathways in MC3T3-E1 Cells., PMID:40343669
Drugs targeting novel pathways in pulmonary arterial hypertension., PMID:40341051
Antioxidant Potential of Gallic Acid Prevents Di-2-ethyhexyl Phthalate-induced Inhibition of Osteogenic Differentiation., PMID:40296616
Bimodal specificity of TF-DNA recognition in embryonic stem cells., PMID:40287827
Melatonin Promotes Cerebral Angiogenesis in Ischemic Mice via BMP6/Smad1/5/9 Pathway., PMID:40274709
G protein-coupled receptor 35 suppresses oxidative stress response 1 in diabetic wound healing., PMID:40267342
ACVR1 drives neuropathic pain by regulating NLRP3-Induced neuronal pyroptosis through the p38 and Smad1/5/8 pathways., PMID:40250754
Biglycan deficiency alleviates intestinal fibrosis through BMP-7-mediated Smad1/5/8 signaling., PMID:40249230
Beyond Repetition: The Role of Gray Zone Alleles in the Upregulation of FMR1-Binding miR-323a-3p and the Modification of BMP/SMAD-Pathway Gene Expression in Human Granulosa Cells., PMID:40244008
Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells., PMID:40194969
BMP2 expression in oral squamous cell carcinoma and its effects on SCC9 cell biological behavior., PMID:40185978
Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis., PMID:40166328
GDF15 promotes trophoblast invasion and pregnancy success via the BMPR1A/BMPR2/p-SMAD1 pathway: Implications for recurrent miscarriage., PMID:40157640
The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma., PMID:40148468
The Role of BMP2/4 in Intestinal Ischemia-Reperfusion Injury: Bridging Smad1/5 and Notch Pathways via Smad6., PMID:40134367
Autocrine GDF10 Inhibits Hepatic Stellate Cell Activation via BMPR2/ALK3 Receptor to Prevent Liver Fibrosis., PMID:40125634
Rare but specific: 5-bp composite motifs define SMAD binding in BMP signaling., PMID:40082964
Expression Patterns of SMAD1-8 in the Peripheral Facial Nerve Following Compressive Nerve Injury or Axotomy., PMID:40076910
Sonic Hedgehog potentiates BMP9-induced osteogenic differentiation of mesenchymal stem cells., PMID:40070367
Spontaneous bone regeneration achieved through one-step alignment of human mesenchymal stem cell-embedded collagen., PMID:40054649
The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway., PMID:40045149
ActRII or BMPR ligands inhibit skeletal myoblast differentiation, and BMPs promote heterotopic ossification in skeletal muscles in mice., PMID:39994804
PROTAC based targeted degradation of LRG1 for mitigating corneal neovascularization., PMID:39993640
LncIMF1 Promotes Adipogenesis of Porcine Intramuscular Preadipocyte by Sponging miR-187., PMID:39961961
MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo., PMID:39956898
Rubiadin Mediates the Upregulation of Hepatic Hepcidin and Alleviates Iron Overload via BMP6/SMAD1/5/9-Signaling Pathway., PMID:39941155
Cistanche deserticola polysaccharides enhance female germline stem cell differentiation through BMP/SMAD signaling to mitigate premature ovarian failure., PMID:39938839
TGF-β1 Induces Mucosal Mast Cell Genes and is Negatively Regulated by the IL-3/ERK1/2 Axis., PMID:39934802
TRIB3 mediates vascular calcification by facilitating self-ubiquitination and dissociation of Smurf1 in chronic kidney disease., PMID:39932798
Short-term effects of subacute ruminal acidosis on ferroptosis and iron metabolism in the livers of lactating sheep fed a high-grain diet., PMID:39890062
Bone morphogenetic protein-4 induced matrix turnover and osteogenic differentiation-related molecules of stem cells from apical papilla and its associated ALK/Smad signaling., PMID:39873078
Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex., PMID:39844165
FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia., PMID:39837840
Evaluating the transcriptional regulators of arterial gene expression via a catalogue of characterized arterial enhancers., PMID:39819837
1,8-Cineole reduces pulmonary vascular remodelling in pulmonary arterial hypertension by restoring intercellular communication and inhibiting angiogenesis., PMID:39813848
Ghrelin Induces Ferroptosis Resistance and M2 Polarization of Microglia to Alleviate Neuroinflammation and Cognitive Impairment in Alzheimer's Disease., PMID:39797928
Bone-brain communication mediates the amelioration of Polgonatum cyrtonema Hua polysaccharide on fatigue in chronic sleep-deprived mice., PMID:39793823
A Recombinant Antibody Against ALK2 Promotes Tissue Iron Redistribution and Contributes to Anemia Resolution in a Mouse Model of Anemia of Inflammation., PMID:39791515
Exosomal NEDD4L derived from HG+oxLDL-induced vascular endothelial cells accelerates macrophage M1 polarization and oxLDL uptake by ubiquitinating IκBα and PPARγ., PMID:39775116
Slit1 Promotes Hypertrophic Scar Formation Through the TGF-β Signaling Pathway., PMID:39768930
For research use only. Not for human or drug use.
