Catalog No.
YHH18601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu24-Phe308
Predicted molecular weight
34.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15759
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAP kinase 11, Mitogen-activated protein kinase p38 beta, MAPK 11, Mitogen-activated protein kinase 11, PRKM11, SAPK2B, Stress-activated protein kinase 2b, MAP kinase p38 beta, MAPK11, p38b, p38-2, SAPK2, SAPK2b
Daily acute intermittent hypoxia elicits age & sex-dependent changes in molecules regulating phrenic motor plasticity., PMID:40204197
Tiliroside from Lagopsis supina Ameliorates Myocardial Ischemia Injury in Zebrafish by Activating the kdr-Mediated PI3K-Akt and MAPK Signaling Pathways., PMID:40076931
Kinase Inhibitor-Induced Cell-Type Specific Vacuole Formation in the Absence of Canonical ATG5-Dependent Autophagy Initiation Pathway., PMID:39895059
Bryostatin-1 enhances the proliferation and functionality of exhausted CD8+ T cells by upregulating MAP Kinase 11., PMID:39877358
Activation of P38 MAPK Signaling Cascade is Linked with Clinical Outcomes and Therapeutic Responses in Human Cancers., PMID:39865029
Novel kinase regulators of extracellular matrix internalisation identified by high-content screening modulate invasive carcinoma cell migration., PMID:39666682
Proteomic analysis of the combined effects of cannabigerol and 3-O-ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes., PMID:39537961
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
Identification of critical genes associated with oxidative stress pathways in benzene-induced hematotoxicity., PMID:39170214
ANXA5 predicts prognosis and immune response and mediates proliferation and migration in head and neck squamous cell carcinoma., PMID:39168258
Transcriptome Profiling of Mouse Embryonic Fibroblast Spontaneous Immortalization: A Comparative Analysis., PMID:39125691
Dietary lipid sources affect growth performance, lipid deposition, antioxidant capacity and inflammatory response of largemouth bass (Micropterus salmoides)., PMID:38754648
The Invasion Factor ODZ1 Is Upregulated through an Epidermal Growth Factor Receptor-Induced Pathway in Primary Glioblastoma Cells., PMID:38727302
TSPAN8+ myofibroblastic cancer-associated fibroblasts promote chemoresistance in patients with breast cancer., PMID:38569015
Proline-directed yeast and human MAP kinases phosphorylate the Dot1p/DOT1L histone H3K79 methyltransferase., PMID:38270553
Chicken miR-148a-3p regulates immune responses against AIV by targeting the MAPK signalling pathway and IFN-γ., PMID:37993949
Red Kale (Brassica oleracea L. ssp. acephala L. var. sabellica) Induces Apoptosis in Human Colorectal Cancer Cells In Vitro., PMID:37836781
Illuminating (HTLV-1)-induced adult T-cell leukemia/lymphoma transcriptomic signature: A systems virology approach., PMID:37832654
Transcription factor ETV4 promotes the development of hepatocellular carcinoma by driving hepatic TNF-α signaling., PMID:37670477
Anthracycline cardiotoxicity is exacerbated by global p38β genetic ablation in a sexually dimorphic manner but unaltered by cardiomyocyte-specific p38α loss., PMID:37624097
Integrated Transcriptome and Molecular Docking to Identify the Hub Superimposed Attenuation Targets of Curcumin in Breast Cancer Cells., PMID:37569854
Phosphorylated MAPK11 promotes the progression of clear cell renal cell carcinoma by maintaining RUNX2 protein abundance., PMID:37525479
Identifying Patients With Rapid Progression From Hormone-Sensitive to Castration-Resistant Prostate Cancer: A Retrospective Study., PMID:37394064
MAPK11 (p38β) is a major determinant of cellular radiosensitivity by controlling ionizing radiation-associated senescence: An in vitro study., PMID:37346275
SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication., PMID:37345956
P38 kinase in gastrointestinal cancers., PMID:37248432
Construction and integrated analysis of the ceRNA network hsa_circ_0000672/miR-516a-5p/TRAF6 and its potential function in atrial fibrillation., PMID:37169841
A machine learning method for the identification and characterization of novel COVID-19 drug targets., PMID:37137934
Integration of transcriptomics, metabolomics, and lipidomics reveals the mechanisms of doxorubicin-induced inflammatory responses and myocardial dysfunction in mice., PMID:37087977
Jinfeng pills ameliorate premature ovarian insufficiency induced by cyclophosphamide in rats and correlate to modulating IL-17A/IL-6 axis and MEK/ERK signals., PMID:36775079
p38 Mitogen-Activated Protein Kinase Signaling Enhances Reovirus Replication by Facilitating Efficient Virus Entry, Capsid Uncoating, and Postuncoating Steps., PMID:36744961
An induced pluripotent stem cell-based model identifies molecular targets of vincristine neurotoxicity., PMID:36518084
Transcriptional data analysis reveals the association between infantile hemangiomas and venous malformations., PMID:36338963
Single-Cell Transcriptomics of Endothelial Cells in Upper and Lower Human Esophageal Squamous Cell Carcinoma., PMID:36290884
Microarray meta-analysis reveals IL6 and p38β/MAPK11 as potential targets of hsa-miR-124 in endothelial progenitor cells: Implications for stent re-endothelization in diabetic patients., PMID:36176980
Results of untargeted analysis using the SOMAscan proteomics platform indicates novel associations of circulating proteins with risk of progression to kidney failure in diabetes., PMID:35618095
Design, Synthesis, and Structure-Activity Relationship Study of Potent MAPK11 Inhibitors., PMID:35011435
The exploitation of host autophagy and ubiquitin machinery by Mycobacterium tuberculosis in shaping immune responses and host defense during infection., PMID:35000542
Identification of Hub Genes Associated With Tuberculous Pleurisy by Integrated Bioinformatics Analysis., PMID:34925441
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas., PMID:34814904
Differential Expression of the Sphingolipid Pathway Is Associated with Sensitivity to the PP2A Activator FTY720 in Colorectal Cancer Cell Lines., PMID:34768523
The Role of p38γ in Cancer: From review to outlook., PMID:34671218
Comprehensive Analysis of a Nine-Gene Signature Related to Tumor Microenvironment in Lung Adenocarcinoma., PMID:34540825
p38β - MAPK11 and its role in female cancers., PMID:34174910
Analysis of miRNA and mRNA reveals core interaction networks and pathways of dexamethasone-induced immunosuppression in chicken bursa of Fabricius., PMID:33711668
Phosphorylation of SNX27 by MAPK11/14 links cellular stress-signaling pathways with endocytic recycling., PMID:33605979
MAPK11 regulates seed germination and ABA signaling in tomato by phosphorylating SnRKs., PMID:33448300
Mitogen-activated protein kinase 11 (MAPK11) maintains growth and photosynthesis of potato plant under drought condition., PMID:33388892
p38β (MAPK11) mediates gemcitabine-associated radiosensitivity in sarcoma experimental models., PMID:33310004
Identification of potential mRNA panels for severe acute respiratory syndrome coronavirus 2 (COVID-19) diagnosis and treatment using microarray dataset and bioinformatics methods., PMID:33251083
For research use only. Not for human or drug use.
