Catalog No.
YHH18201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr1748-Glu1914
Predicted molecular weight
20.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15746
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MLCK1, smMLCK, MYLK1, KRP, Kinase-related protein, MLCK, MYLK, Myosin light chain kinase, smooth muscle, Telokin
The Expression and Molecular Roles of MAMDC2 in MSS Colorectal Cancer with a High Tumor Stromal Ratio., PMID:40427044
Identification of Selected Genes Associated With the Prediction of Prognosis in Bladder Cancer., PMID:40370233
Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique., PMID:40171441
MYLK-AS1 improves fracture by targeting miR-146a-5p to regulate cell viability and apoptosis in osteoblasts., PMID:40108718
Declining activity of serum response factor in aging aorta in relation to aneurysm progression., PMID:40081573
Overexpression of LMOD1 induces oxidative stress and enhances cell apoptosis of melanoma through the RIG-I like receptor pathway., PMID:40068386
A 5-lncRNA signature predicts clinical prognosis and demonstrates a different mRNA expression in adult soft tissue sarcoma., PMID:39974396
JNK Inhibition Overcomes Resistance of Metastatic Tetraploid Cancer Cells to Irradiation-Induced Apoptosis., PMID:39940976
Integrated Transcriptomic and Metabolomic Analysis of Rat PASMCs Reveals the Underlying Mechanism for Pulmonary Arterial Hypertension., PMID:39901736
Exploring markers in nursing care of prostate cancer., PMID:39854742
Genes Related to Motility in an Ionizing Radiation and Estrogen Breast Cancer Model., PMID:39596804
Alternative polyadenylation landscape of longissimus dorsi muscle with high and low intramuscular fat content in cattle., PMID:39565284
Differential Analysis of Pathogenic Variants in Thoracic Aortic Aneurysm and Dissection at Different Ages., PMID:39546729
Genetic insights from a Brazilian cohort of aortopathies through targeted next-generation sequencing and FBN1 direct sequencing., PMID:39511342
Loss of myosin light chain kinase induces the cellular senescence associated secretory phenotype to promote breast epithelial cell migration., PMID:39468273
CT45A1-mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell-in-cell structure, potentiating the progression of microsatellite instability-high colorectal cancer., PMID:39322998
Identification and Benchmarking of Myokinasib-II as a Selective and Potent Chemical Probe for Exploring MLCK1 Inhibition., PMID:39302825
Heat Stress Induces Alterations in Gene Expression of Actin Cytoskeleton and Filament of Cellular Components Causing Gut Disruption in Growing-Finishing Pigs., PMID:39272260
Correction to "LncRNA MYLK antisense RNA 1 activates cell division cycle 42/Neutal Wiskott-Aldrich syndrome protein pathway via microRNA-101-5p to accelerate epithelial-to-mesenchymal transition of colon cancer cells"., PMID:39228279
Targeting AGTPBP1 inhibits pancreatic cancer progression via regulating microtubules and ERK signaling pathway., PMID:39129004
JAK inhibition with tofacitinib rapidly increases contractile force in human skeletal muscle., PMID:39122555
Activation of the ROCK/MYLK Pathway Affects Complex Molecular and Morphological Changes of the Trabecular Meshwork Associated With Ocular Hypertension., PMID:39115865
Mutational and transcriptional profile predicts the prognosis of stage IV gastric cancer - Prognostic factors for metastatic gastric cancer., PMID:39043541
Aging aggravates aortic aneurysm and dissection via miR-1204-MYLK signaling axis in mice., PMID:39013850
Targeted next-generation sequencing reveals the genetic mechanism of Chinese Marfan syndrome cohort with ocular manifestation., PMID:38958168
[Mechanism and compatibility efficacy of Astragali Radix-Chuanxiong Rhizoma drug pair in treating ischemic stroke based on network regulation]., PMID:38812133
An effective urobilin clearance strategy based on paramagnetic beads facilitates microscale proteomic analysis of urine., PMID:38775334
Kinase activities in pancreatic ductal adenocarcinoma with prognostic and therapeutic avenues., PMID:38650175
A novel SIK2 inhibitor SIC-19 exhibits synthetic lethality with PARP inhibitors in ovarian cancer., PMID:38518726
AP-1/C-FOS and AP-1/FRA2 differentially regulate early and late adipogenic differentiation of mesenchymal stem cells., PMID:38440920
IGF2BP3-mediated enhanced stability of MYLK represses MSC adipogenesis and alleviates obesity and insulin resistance in HFD mice., PMID:38196046
The SNHG12/microRNA-15b-5p/MYLK axis regulates vascular smooth muscle cell phenotype to affect intracranial aneurysm formation., PMID:38081409
Inhibition of non-muscular myosin light chain kinase accelerates the clearance of inflammatory cells by promoting the lysosome-mediated cell death., PMID:38056232
Hub biomarkers in ultrasound-guided bladder cancer and osteosarcoma: Myosin light chain kinase and caldesmon., PMID:38050320
MYLK and CALD1 as molecular targets in bladder cancer., PMID:38013282
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway., PMID:37951955
LncRNA MYLK antisense RNA 1 activates cell division cycle 42/Neutal Wiskott-Aldrich syndrome protein pathway via microRNA-101-5p to accelerate epithelial-to-mesenchymal transition of colon cancer cells., PMID:37950620
Itga8-Cre-mediated deletion of YAP and TAZ impairs bladder contractility with minimal inflammation and chondrogenic differentiation., PMID:37927241
Aortic dissection in a young male with persistent ductus arteriosus and a novel variant in MYLK., PMID:37921548
Enhanced ileum function in weaned piglets via Laminaria digitata and alginate lyase dietary inclusion: A combined proteomics and metabolomics analysis., PMID:37775079
Chitosan-gentamicin conjugate attenuates heat stress-induced intestinal barrier injury via the TLR4/STAT6/MYLK signaling pathway: In vitro and in vivo studies., PMID:37739521
Effect of pH and lipopolysaccharide on tight junction regulators and inflammatory markers in intestinal cells as an experimental model of weaning transition in dairy calves., PMID:37727241
GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment., PMID:37723567
Novel Long Noncoding RNAs, LINC01093 and MYLK-AS1, Serve as Potential Diagnostic and Prognostic Biomarkers or Hepatocellular Carcinoma., PMID:37527208
Protein expression of S100A2 reveals it association with patient prognosis and immune infiltration profile in colorectal cancer., PMID:37476187
An erythrocyte-centric view on the MFSD2B sphingosine-1-phosphate transporter., PMID:37390971
Determining the Potential Roles of Branched-Chain Amino Acids in the Regulation of Muscle Growth in Common Carp (Cyprinus carpio) Based on Transcriptome and MicroRNA Sequencing., PMID:37303609
Use of whole genome sequencing to determine the genetic basis of visceral myopathies including Prune Belly syndrome., PMID:37288276
Identification of the hub genes associated with prostate cancer tumorigenesis., PMID:37251946
For research use only. Not for human or drug use.
