Catalog No.
YHH11401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln65-Gly299
Predicted molecular weight
28.37 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15493
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GNL, Senescence marker protein 30, SMP-30, Gluconolactonase, Regucalcin, RGN, SMP30, RC
Extracellular regucalcin reveals anti-cancer activity by suppressing cell growth and metastatic activity by blocking EGF signaling pathway in human glioblastoma cells in vitro., PMID:40318797
Effect of electromagnetic field radiation on transcriptomic profile and DNA methylation level in pig conceptuses during the peri-implantation period., PMID:40269194
SOS1 inhibitor BI-3406 shows in vivo antitumor activity akin to genetic ablation and synergizes with a KRASG12D inhibitor in KRAS LUAD., PMID:40073053
Threonine and tyrosine kinase promotes multiple myeloma progression by regulating regucalcin expression., PMID:39961467
Low Expression of FAM96B is Associated with Poor Prognosis in Hepatocellular Carcinoma., PMID:39697039
SMP30 Alleviates Oxidative Stress and Regulates Ca2+-ATPase Activity in UVR-B-Induced Cataracts in Rats., PMID:39690481
Downregulated Regucalcin Expression Induces a Cancer-like Phenotype in Non-Neoplastic Prostate Cells and Augments the Aggressiveness of Prostate Cancer Cells: Interplay with the G Protein-Coupled Oestrogen Receptor?, PMID:39682121
Factors Influencing Nerinetide Effect on Infarct Volume in Patients Without Alteplase in the Randomized ESCAPE-NA1 Trial., PMID:39648909
Admission hyperglycemia effect on symptomatic intracranial hemorrhage in tenecteplase versus alteplase before large vessel occlusion stroke thrombectomy., PMID:39312003
Alterations of plasma metabolomes and their correlations with immunogenicity in maintenance hemodialysis patients receiving different COVID-19 vaccine regimens., PMID:39161065
Tenecteplase versus alteplase before stroke thrombectomy: outcomes after system-wide transitions in Pennsylvania., PMID:38960948
Gn protein expressed in plants for diagnosis of severe fever with thrombocytopenia syndrome virus., PMID:38639795
Effects of L-Leu-L-Leu peptide on growth, proliferation, and apoptosis in broiler intestinal epithelial cells., PMID:38457989
E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner., PMID:38414029
An international multicenter study comparing COVID-19 omicron outcomes in patients with hematological malignancies treated with obinutuzumab versus rituximab., PMID:38400683
A Chronic Increase in Blood-Brain Barrier Permeability Facilitates Intraneuronal Deposition of Exogenous Bloodborne Amyloid-Beta1-42 Peptide in the Brain and Leads to Alzheimer's Disease-Relevant Cognitive Changes in a Mouse Model., PMID:38393907
Intravenous Tirofiban Versus Alteplase Before Endovascular Treatment in Acute Ischemic Stroke: A Pooled Analysis of the DEVT and RESCUE BT Trials., PMID:38362756
Release of SMP30 in Extracellular Vesicles under Conditions of Ascorbic Acid Deficiency Is Involved with Acute Phase Response in ODS Rat., PMID:38171814
Intra-arterial tenecteplase following endovascular therapy in patients with acute posterior circulation arterial occlusion: study protocol and rationale., PMID:38124230
Anti-biofilm potential of human senescence marker protein 30 against Mycobacterium smegmatis., PMID:38114754
Regucalcin Is a Potential Regulator in Human Cancer: Aiming to Expand into Cancer Therapy., PMID:38001749
Integrative proteome and metabolome analyses reveal molecular basis underlying growth and nutrient composition in the Pacific oyster, Crassostrea gigas., PMID:37838097
Development of Zika Virus Mini-Replicon Based Single-Round Infectious Particles as Gene Delivery Vehicles., PMID:37632104
Uroplakin 1a Interacts with Regucalcin and Proteasome Subunit Beta 1., PMID:37468792
Structural and photophysical characterization of the small ultra-red fluorescent protein., PMID:37438348
Impact of REAC Regenerative Endogenous Bioelectrical Cell Reprogramming on MCF7 Breast Cancer Cells., PMID:37374009
SARS-CoV-2 Omicron subvariant spike N405 unlikely to rapidly deamidate., PMID:37178506
RGN as a prognostic biomarker with immune infiltration and ceRNA in lung squamous cell carcinoma., PMID:37161020
Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma., PMID:36928883
Early Detection of Alzheimer's Disease-Related Pathology Using a Multi-Disease Diagnostic Platform Employing Autoantibodies as Blood-Based Biomarkers., PMID:36847005
GUS Reporter-Aided Promoter Deletion Analysis of A. thaliana POLYAMINE OXIDASE 3., PMID:36768644
Metabolic Hijacking of Hexose Metabolism to Ascorbate Synthesis Is the Unifying Biochemical Basis of Murine Liver Fibrosis., PMID:36766828
Randomised phase 2 study (JADE) of the HBV capsid assembly modulator JNJ-56136379 with or without a nucleos(t)ide analogue in patients with chronic hepatitis B infection., PMID:36697207
Senescence in oral lichen planus as assessed by the immunohistochemical evaluation of senescence marker protein-30 (Regucalcin)., PMID:36656203
Triglyceride content of lipoprotein subclasses and kidney hemodynamic function and injury in adolescents with type 1 diabetes., PMID:36623423
0.1% RGN-259 (Thymosin ß4) Ophthalmic Solution Promotes Healing and Improves Comfort in Neurotrophic Keratopathy Patients in a Randomized, Placebo-Controlled, Double-Masked Phase III Clinical Trial., PMID:36613994
Reviewing Collagen Supplements: Independent nurse prescriber Caroline Hall explores the literature around collagen supplementation in aesthetics., PMID:36583588
Functional pleiotropy of calcium binding protein Regucalcin in signaling and diseases., PMID:36442591
SMP30-mediated synthesis of vitamin C activates the liver PPARα/FGF21 axis to regulate thermogenesis in mice., PMID:36434042
RGN: Residue-Based Graph Attention and Convolutional Network for Protein-Protein Interaction Site Prediction., PMID:36398714
Ruscogenin Protects Against Deoxynivalenol-Induced Hepatic Injury by Inhibiting Oxidative Stress, Inflammation, and Apoptosis Through the Nrf2 Signaling Pathway: An In vitro Study., PMID:36247053
Single-sequence protein structure prediction using a language model and deep learning., PMID:36192636
Proteomic analysis of the liver regulating lipid metabolism in Chaohu ducks using two-dimensional electrophoresis., PMID:36060646
Antisenescence effect of REAC biomodulation to counteract the evolution of myelodysplastic syndrome., PMID:35899943
A Reverse Mutation E143K within the PrM Protein of Zika Virus Asian Lineage Natal RGN Strain Increases Infectivity and Cytopathicity., PMID:35891552
Senescence marker protein30 protects lens epithelial cells against oxidative damage by restoring mitochondrial function., PMID:35615975
Correlation of von Willebrand factor and platelets with acute ischemic stroke etiology and revascularization outcome: an immunohistochemical study., PMID:35595407
The mechanism and effects of remdesivir-induced developmental toxicity in zebrafish: Blood flow dysfunction and behavioral alterations., PMID:35560222
Avelumab First-Line Maintenance Treatment in Advanced Bladder Cancer: Practical Implementation Steps for Infusion Nurses., PMID:35537002
Overexpression of regucalcin blocks the migration, invasion, and bone metastatic activity of human prostate cancer cells: Crosstalk between cancer cells and bone cells., PMID:35365850
For research use only. Not for human or drug use.
