Catalog No.
YHH08401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro51-Arg303
Predicted molecular weight
31.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15391
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GPR105, P2RY14, UDP-glucose receptor, KIAA0001, G-protein coupled receptor 105, P2Y14, P2Y purinoceptor 14
Unraveling the immune activation mechanisms of DAMPs in coronary artery disease through transcriptomic and single-cell analyses., PMID:40306092
Construction and validation of a comprehensive metabolism-associated prognostic model for predicting survival and immunotherapy benefits in ovarian cancer., PMID:39440060
NF1-dependent disruption of the blood-nerve-barrier is improved by blockade of P2RY14., PMID:39100928
Machine learning-based screening and validation of liver metastasis-specific genes in colorectal cancer., PMID:39085446
Single-nucleus RNA-seq identifies one galanin neuronal subtype in mouse preoptic hypothalamus activated during recovery from sleep deprivation., PMID:38703367
ARDS and aging: TYMS emerges as a promising biomarker and therapeutic target., PMID:38558817
UDP-Glucose/P2Y14 Receptor Signaling Exacerbates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats., PMID:38525592
Identification and verification of feature biomarkers associated with immune cells in recurrent pregnancy loss., PMID:38305600
Exploring Prognostic Immune Microenvironment-Related Genes in Head and Neck Squamous Cell Carcinoma from the TCGA Database., PMID:38213736
The combined signatures of G protein-coupled receptor family and immune landscape provide a prognostic and therapeutic biomarker in endometrial carcinoma., PMID:37584707
A comprehensive analysis of biomarkers associated with synovitis and chondrocyte apoptosis in osteoarthritis., PMID:37545537
Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice., PMID:37250906
ncRNA-mediated low expression of P2RY14 correlates with poor prognosis and tumor immune infiltration in ovarian carcinoma., PMID:36760244
Identification of potential biomarkers in Barrett's esophagus derived esophageal adenocarcinoma., PMID:36759514
Identification of immune associated potential molecular targets in proliferative diabetic retinopathy., PMID:36658547
Expression of the pro-inflammatory P2Y14 receptor in the non-vasectomized and vasectomized human epididymis., PMID:36029226
Identifying key genes and functionally enriched pathways in Th2-high asthma by weighted gene co-expression network analysis., PMID:35550122
The purinergic P2Y14 receptor links hepatocyte death to hepatic stellate cell activation and fibrogenesis in the liver., PMID:35385339
P2RY14 cAMP signaling regulates Schwann cell precursor self-renewal, proliferation, and nerve tumor initiation in a mouse model of neurofibromatosis., PMID:35311647
Identification of Impacted Pathways and Transcriptomic Markers as Potential Mediators of Pulmonary Fibrosis in Transgenic Mice Expressing Human IGFBP5., PMID:34830489
Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion., PMID:34385262
P2RY14 Is a Potential Biomarker of Tumor Microenvironment Immunomodulation and Favorable Prognosis in Patients With Head and Neck Cancer., PMID:34306014
Adipocyte P2Y14 receptors play a key role in regulating whole-body glucose and lipid homeostasis., PMID:34027896
MicroRNA-363-3p promote the development of acute myeloid leukemia with RUNX1 mutation by targeting SPRYD4 and FNDC3B., PMID:33950983
UDP-glucose and P2Y14 receptor amplify allergen-induced airway eosinophilia., PMID:33792561
CCR4, CCR8, and P2RY14 as Prognostic Factors in Head and Neck Squamous Cell Carcinoma Are Involved in the Remodeling of the Tumor Microenvironment., PMID:33692955
UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells., PMID:33011563
Role of UDP-Sugar Receptor P2Y14 in Murine Osteoblasts., PMID:32326617
Proinflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice., PMID:32287042
Insights regarding novel biomarkers and the pathogenesis of primary colorectal carcinoma based on bioinformatic analysis., PMID:32058945
P2 receptors mRNA expression profiles in macrophages from ankylosing spondylitis patients and healthy individuals., PMID:31884692
Integrative genomics analysis of hub genes and their relationship with prognosis and signaling pathways in esophageal squamous cell carcinoma., PMID:31485619
Development of novel predictive miRNA/target gene pathways for colorectal cancer distance metastasis to the liver using a bioinformatic approach., PMID:30807603
Modulation of blood inflammatory markers by benralizumab in patients with eosinophilic airway diseases., PMID:30658649
Candidate gene and pathway analyses identifying genetic variations associated with prasugrel pharmacokinetics and pharmacodynamics., PMID:30458339
Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression., PMID:29951132
Identification of key genes related to high-risk gastrointestinal stromal tumors using bioinformatics analysis., PMID:29578181
P2Y14 receptor activation decreases interleukin-6 production and glioma GL261 cell proliferation in microglial transwell cultures., PMID:29189936
The expression of P2Y14, a purinergic G-protein coupled receptor, defines functionally distinct subpopulations in placenta-derived hematopoietic stem progenitor cells., PMID:28804125
Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y1 and P2Y14 receptors in mice., PMID:28487256
Effects of Lithium Monotherapy for Bipolar Disorder on Gene Expression in Peripheral Lymphocytes., PMID:27867936
Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling., PMID:27554816
Functional screen identifies regulators of murine hematopoietic stem cell repopulation., PMID:26880577
UTP activates small-conductance Ca2+-activated K+ channels in murine detrusor PDGFRα+ cells., PMID:26202222
Renal intercalated cells sense and mediate inflammation via the P2Y14 receptor., PMID:25799465
The G protein-coupled receptor P2Y14 influences insulin release and smooth muscle function in mice., PMID:24993824
Purinergic P2Y₁₄ receptor modulates stress-induced hematopoietic stem/progenitor cell senescence., PMID:24937426
Loss of P2Y₁₄ results in an arresting response to hematological stress., PMID:24937422
Characterization of the contractile P2Y14 receptor in mouse coronary and cerebral arteries., PMID:24911208
Selective induction of P2Y14 receptor by RANKL promotes osteoclast formation., PMID:24048691
For research use only. Not for human or drug use.
