Catalog No.
YHH03101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr651-Gln876
Predicted molecular weight
28.69 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15139
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PRKD1, Protein kinase D, nPKC-D1, Protein kinase C mu type, PKD1, PKD, nPKC-mu, PRKCM, Serine/threonine-protein kinase D1
Note
For research use only.
MiR-375 promotes cisplatin sensitivity of lung adenocarcinoma., PMID:37625279
Protein kinase D2 confers neuroprotection by promoting AKT and CREB activation in ischemic stroke., PMID:37730136
The role of PKC and PKD in CXCL12 and CXCL13 directed malignant melanoma and acute monocytic leukemic cancer cell migration., PMID:37949381
Role of protein kinase D1 in vasoconstriction and haemodynamics in rats., PMID:37963515
PKD knockdown mitigates Ang II-induced cardiac hypertrophy and ferroptosis via the JNK/P53 signaling pathway., PMID:37972803
Protein kinase D1 - A targetable mediator of pancreatic cancer development., PMID:38061566
A role for mutations in AK9 and other genes affecting ependymal cells in idiopathic normal pressure hydrocephalus., PMID:38100419
Protein kinase D (PKD) on the crossroad of lipid absorption, synthesis and utilization., PMID:38104800
The mechanism of 25-hydroxycholesterol-mediated suppression of atrial β1-adrenergic responses., PMID:38253680
Metabolic remodeling in cardiac hypertrophy and heart failure with reduced ejection fraction occurs independent of transcription factor EB in mice., PMID:38259303
Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010
Effect of deletion of the protein kinase PRKD1 on development of the mouse embryonic heart., PMID:38419169
Sorting of secretory proteins at the trans-Golgi network by human TGN46., PMID:38466628
Association between Single Nucleotide Polymorphisms of PRKD1 and KCNQ3 Gene and Milk Quality Traits in Gannan Yak (Bos grunniens)., PMID:38472894
Protein Kinase D Plays a Crucial Role in Maintaining Cardiac Homeostasis by Regulating Post-Translational Modifications of Myofilament Proteins., PMID:38474037
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals., PMID:38489359
Adeno-associated virus-based approach for genetic modification of cardiac fibroblasts in adult rat hearts., PMID:38538007
Shared Features Underlying Compact Genomes and Extreme Habitat Use in Chironomid Midges., PMID:38662498
PRKD1-related telangiectasia-ectodermal dysplasia-brachydactyly-cardiac anomaly syndrome: Case report and review of the literature., PMID:38677542
Protein kinase-D1 and downstream signaling mechanisms involved in GLUT4 translocation in cardiac muscle., PMID:38723678
A Novel Gene Fusion YLPM1::PRKD1 Identified in a Cribriform Subtype of Polymorphous Adenocarcinoma., PMID:38735907
Internalized β2-Adrenergic Receptors Oppose PLC-Dependent Hypertrophic Signaling., PMID:38813686
Calcium plays an essential role in early-stage dendrite injury detection and regeneration., PMID:38825174
Prkd1 regulates the formation and repair of plasma membrane disruptions (PMD) in osteocytes., PMID:38866124
Natural variation in protein kinase D modifies alcohol sensitivity in Caenorhabditis elegans., PMID:38895441
Genetic Rearrangements in Different Salivary Gland Tumors: A Systematic Review., PMID:38966479
Benzo(a)pyrene exposure impacts cerebrovascular development in zebrafish embryos and the antagonistic effect of berberine., PMID:39053545
The role of protein kinase D (PKD) in obesity: Lessons from the heart and other tissues., PMID:39128598
Getting smart - Deciphering the neuronal functions of protein kinase D., PMID:39147241
Novel autosomal recessive SINO syndrome-associated KIDINS220 variants provide insight into the genotype-phenotype correlation., PMID:39296002
Protein kinase D2 modulates hepatic insulin sensitivity in male mice., PMID:39401614
Potential Prognostic Role of Protein Kinase D Isoforms in Head and Neck Cancers., PMID:39408603
Protein kinase D1 mitigation against etoposide induced DNA damage in prostate cancer is associated with increased α-Catenin., PMID:39428693
Protein kinase D1 in myeloid lineage cells contributes to the accumulation of CXCR3+CCR6+ nonconventional Th1 cells in the lungs and potentiates hypersensitivity pneumonitis caused by S. rectivirgula., PMID:39464896
Sphingosine-1-phosphate activates LRRC8 volume-regulated anion channels through Gβγ signalling., PMID:39496493
Inhibition of protein kinase D and its substrate phosphatidylinositol-4 kinase III beta blocks common human coronavirus replication., PMID:39540754
Stress and Obesity Signaling Converge on CREB Phosphorylation to Promote Pancreatic Cancer., PMID:39642318
Phosphorylation of Optineurin by protein kinase D regulates Parkin-dependent mitophagy., PMID:39669425
PRKD3 promotes proliferation of liver cancer cells: a downstream proteomics profiling study., PMID:39678603
Brain calcification in congenital heart defects and ectodermal dysplasia (CHDED)., PMID:39740729
Targeting protein kinase D in oral squamous cell carcinoma: a promising therapeutic approach., PMID:39945774
Loss of Cathepsin K impairs collagen biogenesis and enhances actin polymerization in trabecular meshwork., PMID:39990379
Deciphering the transcriptional alterations in high grade serous ovarian cancer upon catalytic inactivation of protein kinase D., PMID:40057070
Tetramethylpyrazine exerts a neuroprotective effect in acute spinal cord injury by mitigating oxidative stress through PKD1: Multi-omics analysis and experimental validation., PMID:40097129
Neurogenic differentiation 2 promotes inflammatory activation of macrophages in doxorubicin-induced myocarditis via regulating protein kinase D., PMID:40102732
Effect of PRKD3 on cell cycle in gastric cancer progression and downstream regulatory networks., PMID:40131654
Syringic Acid in Canarium odontophyllum for Diabetes and Obesity - A Review., PMID:40377865
Adipose tissue protein kinase D (PKD): regulation of signalling networks and its sex-dependent effects on metabolism., PMID:40454664
Down-regulation of neuroprotective protein kinase D in Huntington´s disease., PMID:40461488
Protein Kinase D Knockdown Alleviates Vascular Calcification Through P53-SLC7A11 Axis-Mediated Ferroptosis., PMID:40474563
For research use only. Not for human or drug use.
