Catalog No.
YHH02701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu182-Gly296
Predicted molecular weight
14.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15124
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PGMRP, Aciculin, Phosphoglucomutase-related protein, PGM-RP, PGM5, Phosphoglucomutase-like protein 5
Phosphoglucomutase 5 gene transcripts are expressed by the human placenta and differentially regulated in placental dysfunction., PMID:40180976
Tumour protein p53-activated lncRNA PGM5-AS1 suppresses lung cancer growth and stemness by targeting R-spondin1 via microRNA-1247-5p., PMID:40035308
LncRNA PGM5-AS1 Impairs the Resistance of Cervical Cancer to Cisplatin by Regulating the Hippo and PI3K-AKT Pathways., PMID:39733221
Bivariate genome-wide association study of circulating fibrinogen and C-reactive protein levels., PMID:39299614
CircPGM5 regulates Foxo3a phosphorylation via MiR-21-5p/MAPK10 axis to inhibit bladder cancer progression., PMID:39004326
Codonopsis pilosula polysaccharide alleviates rotenone-induced murine brain organoids death through downregulation of gene body DNA methylation modification in the ZIC4/PGM5/CAMTA1 axis., PMID:38074999
Rewiring of miRNA-mRNA bipartite co-expression network as a novel way to understand the prostate cancer related players., PMID:37018429
Network module function enrichment analysis of lung squamous cell carcinoma and lung adenocarcinoma., PMID:36451444
LncRNA PGM5-AS1 Inhibits the Progression of Bladder Cancer by Regulating miR-587/SLIT3 Axis., PMID:36017912
A bioinformatics analysis: ZFHX4 is associated with metastasis and poor survival in ovarian cancer., PMID:35915456
Downregulation of PGM5 expression correlates with tumor progression and poor prognosis in human prostate cancer., PMID:35819729
Identification of Crucial lncRNAs for Luminal A Breast Cancer through RNA Sequencing., PMID:35692369
Long non-coding RNAs PGM5-AS1 upregulates Decorin (DCN) to inhibit cervical cancer progression by sponging miR-4284., PMID:35420507
Construction and Validation of a Novel Pyroptosis-Related Four-lncRNA Prognostic Signature Related to Gastric Cancer and Immune Infiltration., PMID:35392086
Engineered exosomes for co-delivery of PGM5-AS1 and oxaliplatin to reverse drug resistance in colon cancer., PMID:34463962
Gene expression pattern analysis using dual-color RT-MLPA and integrative genome-wide association studies of eQTL for tuberculosis suscepitibility., PMID:33472618
PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer., PMID:33407592
Structure and Characterization of Phosphoglucomutase 5 from Atlantic and Baltic Herring-An Inactive Enzyme with Intact Substrate Binding., PMID:33287293
Reduced long noncoding RNA PGM5-AS1 facilitated proliferation and invasion of colorectal cancer through sponging miR-100-5p., PMID:32767323
Long non-coding RNA PGM5-AS1 promotes epithelial-mesenchymal transition, invasion and metastasis of osteosarcoma cells by impairing miR-140-5p-mediated FBN1 inhibition., PMID:32412676
The Downregulation of lncRNA pgm5-as1 Inhibits the Proliferation and Metastasis Via Increasing miR-484 Expression in Colorectal Cancer., PMID:32354224
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily., PMID:32221390
Identification of key long non-coding RNAs in gastric adenocarcinoma., PMID:32176636
Transcriptional Profiling of Human Peripheral Blood Mononuclear Cells Identifies Diagnostic Biomarkers That Distinguish Active and Latent Tuberculosis., PMID:31921195
Down-regulation of long noncoding RNA PGM5-AS1 correlates with tumor progression and predicts poor prognosis in clear cell renal cell carcinoma., PMID:31858536
A Comprehensive Survey of Genomic Alterations in Gastric Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets., PMID:31781598
PGM5 is a promising biomarker and may predict the prognosis of colorectal cancer patients., PMID:31582909
Systematic analysis of the intersection of disease mutations with protein modifications., PMID:31345222
PGM5: a novel diagnostic and prognostic biomarker for liver cancer., PMID:31218127
p53-induced long non-coding RNA PGM5-AS1 inhibits the progression of esophageal squamous cell carcinoma through regulating miR-466/PTEN axis., PMID:31185143
Transcriptomic analysis of high-throughput sequencing about circRNA, lncRNA and mRNA in bladder cancer., PMID:30025927
Sequence-structure relationships, expression profiles, and disease-associated mutations in the paralogs of phosphoglucomutase 1., PMID:28837627
Identification of key lncRNAs in colorectal cancer progression based on associated protein-protein interaction analysis., PMID:28797257
[Multiple lncRNAs affect the incidence and
development of melanoma]., PMID:28255113
Targeted Proteomics for Multiplexed Verification of Markers of Colorectal Tumorigenesis., PMID:28062797
[CONSTRUCTION AND PROPERTIES OF THE FRANCISELLA TULARENSIS VACCINE STRAIN WITHOUT ONE COPY OF THE IGLC GENE AND WITHOUT RECA GENE]., PMID:26665740
Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance., PMID:24963132
Neuroprotective changes of thalamic degeneration-related gene expression by acupuncture in an MPTP mouse model of parkinsonism: microarray analysis., PMID:23235115
A new method to identify flanking sequence tags in chlamydomonas using 3'-RACE., PMID:22735168
Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions., PMID:12421752
Aciculin and its relation to dystrophin: immunocytochemical studies in human normal and Duchenne dystrophy quadriceps muscles., PMID:10867799
Characterisation of the promoter which regulates expression of a phosphoglucomutase-related protein, a component of the dystrophin/utrophin cytoskeleton predominantly expressed in smooth muscle., PMID:9342213
Localization of cranin (dystroglycan) at sites of cell-matrix and cell-cell contact: recruitment to focal adhesions is dependent upon extracellular ligands., PMID:9117347
A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily., PMID:8631316
Dystrophin, vinculin, and aciculin in skeletal muscle subject to chronic use and disuse., PMID:8775358
Localization of utrophin and aciculin at sites of cell-matrix and cell-cell adhesion in cultured cells., PMID:7589238
Association of aciculin with dystrophin and utrophin., PMID:7890770
Expression and localization of the phosphoglucomutase-related cytoskeletal protein, aciculin, in skeletal muscle., PMID:7983164
Cloning and molecular characterization of csm mutations allowing expression of catabolite-repressible operons in the absence of exogenous cyclic AMP., PMID:3009405