Catalog No.
YHH01901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile91-Asp274
Predicted molecular weight
22.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15109
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Receptor for advanced glycosylation end products, Advanced glycosylation end product-specific receptor, AGER, RAGE
HMGB1-Platelet Interactions: Mechanisms and Targeted Therapy Strategies., PMID:40514022
Biomarkers of Reversible and Irreversible Pulpitis: Systematic Review and Meta-Analysis., PMID:40511199
Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation., PMID:40510163
Dihydromyricetin May Attenuate Skin Aging as a RAGE Inhibitor., PMID:40507131
Circulating protein biomarkers and their association with vulnerable plaque characteristics - a PROSPECT II substudy., PMID:40503438
l-Cysteine Alleviates Peritoneal Fibrosis by Repressing PKM2 in Peritoneal Mesothelial Cells., PMID:40497367
Syringetin ameliorates thallium sulphate induced renal dysfunction via regulating Nrf2/Keap-1, TLR4/HMGB1/RAGE and NF-κB pathway., PMID:40494130
Linking oxidative stress biomarkers to disease progression and antioxidant therapy in hypertension and diabetes mellitus., PMID:40492113
Rab7 inhibitor enhances stem cell differentiation into keratinocyte-like cells with anti-inflammatory properties., PMID:40491919
RAGE Is Essential for Subretinal Fibrosis in Laser-Induced Choroidal Neovascularization: Therapeutic Implications., PMID:40488713
Serum proteins and faecal microbiota as potential biomarkers in newly diagnosed, treatment-naïve inflammatory bowel disease and irritable bowel syndrome patients., PMID:40481885
Mechanism and implications of advanced glycation end products (AGE) and its receptor RAGE axis as crucial mediators linking inflammation and obesity., PMID:40474023
Investigating the impact of berberine on autophagy-mediated drug resistance in chronic lymphocytic leukemia tumor cells., PMID:40473844
Network pharmacology-based study in polymetformin's new function of blocking ages/rage pathway curing diabetic complications., PMID:40467581
Seeking standardized in vitro models of AGE-RAGE signaling in the physiological perspective of glycated dietary proteins., PMID:40466838
Argyreia nervosa (Brum.f.) Bojer. alleviates diabetes mellitus-induced male infertility., PMID:40465059
A Genetic Perspective to Reveal the Impact of Mitochondrial Dysfunction-related Genes on Diabetic Kidney Disease: A Multi-omics Study., PMID:40464186
Antithrombotic Effect of Ginkgo Biloba Extract: A Study Based on Network Pharmacological Analysis and In vivo Experiments., PMID:40462336
[Network pharmacology and molecular docking explore mechanism of Croci Stigma in treating immune checkpoint inhibitor-associated myocarditis]., PMID:40461207
Integrative Network Pharmacology Prediction of the Mechanisms of Tri-Ka-Tuk: A Traditional Thai Herbal Formula., PMID:40444620
Dietary advanced glycation end-products promote food allergy by disrupting intestinal barrier and enhancing Th2 immunity., PMID:40436880
Effects of metformin on serum miRNA expression and target gene regulation in prediabetic patients., PMID:40436121
Network pharmacology and in-depth blood proteomics reveal the mechanism of Buqi Tongluo capsules in treating bone destruction in osteoarthritis., PMID:40435578
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways., PMID:40435181
Spinach Extract Reduces Kidney Damage in Diabetic Rats by Impairing the AGEs/RAGE Axis., PMID:40429870
Amyloid β-Induced Inflammarafts in Alzheimer's Disease., PMID:40429737
IL-6 signaling regulates the inflammatory response without impacting pathogen burden during influenza-associated pulmonary aspergillosis., PMID:40420617
HMGB1/RAGE signaling mediates the activation of microglia and participates in depressive-like behaviors and cognitive deficits in rats after ischemia-reperfusion., PMID:40419119
Study on the Mechanism of Dihydromyricetin in Alleviating Depressive-Like Behavior in Rats Based on Network Pharmacology., PMID:40418429
Molecular mechanisms of Potentilla Discolor Bunge in regulating ferroptosis to alleviate DKD via the Nrf2 signaling pathway., PMID:40414576
Omarigliptin ameliorates cisplatin-induced renal damage: Cross-talk between glucagon-like peptide-1, HMGB1/RAGE/TLR4 signaling, and TXNIP/NLRP3 inflammasome/gasdermin D axis., PMID:40414557
Identifying RAGE inhibitors as potential therapeutics for Alzheimer's disease via integrated in-silico approaches., PMID:40404684
Clinical significance of serum RAGE levels in anti-CCP-negative rheumatoid arthritis., PMID:40402318
Complement component C4a binds to oxytocin and modulates plasma oxytocin concentrations and social behavior in male mice., PMID:40393160
A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease., PMID:40391501
Cytoplasmic HMGB1 promotes the activation of JAK2-STAT3 signaling and PD-L1 expression in breast cancer., PMID:40389855
Investigating the Mechanism of the Fuzheng Huayu Formula in Treating Cirrhosis through Network Pharmacology, Molecular Docking, and Experimental Verification., PMID:40385224
Calprotectin inhibition attenuates silica-induced lung fibrosis., PMID:40381145
The S100A11-RAGE/TLR4 axis activation mediates inflammatory response and epithelial integrity against Toxoplasma gondii infection in a human placental explant model., PMID:40378774
An Analysis of Effective Components of Pulsatillae radix Using UHPLC-QTOF-MS/MS and Network Pharmacology to Investigate its Effects on Ulcerative Colitis., PMID:40375698
A bioinformatics-driven approach to identify biomarkers and elucidate the pathogenesis of type 2 diabetes concurrent with pulmonary tuberculosis., PMID:40374744
Zn-Based Multi-Active Framework Nanoparticles TSA-CAN-Zn Inhibit Skin Glycation via Dual Blockade of HMGB1/RAGE and AGEs/RAGE Pathways., PMID:40370206
RAGE-Mediated Effects of Formaldehyde in Alzheimer's Disease., PMID:40367077
Inhibiting Immune Crosstalk by Modulation of the Intracellular Function and Extracellular Environment of Diseased Microglia to Boost Parkinson's Disease Therapy., PMID:40366277
Diabetes mellitus aggravates myocardial inflammation and oxidative stress in aortic stenosis: a mechanistic link to HFpEF features., PMID:40361188
Mechanism of ferroptosis in heart failure: The role of the RAGE/TLR4-JNK1/2 pathway in cardiomyocyte ferroptosis and intervention strategies., PMID:40360081
Assessing the toxicological effects and mechanism of plasticizer exposure on inflammatory bowel disease based on network toxicology and molecular docking., PMID:40354873
RAGE gene polymorphism (rs1800625) and type 1 diabetes mellitus: A potential new model for early diagnosis and risk prediction., PMID:40352233
[Mechanism of Colquhounia Root Tablets against diabetic kidney disease via RAGE-ROS-PI3K-AKT-NF-κB-NLRP3 signaling axis]., PMID:40350875
Charged dendrimers reduce glioblastoma viability by modulating lysosomal activity and HMGB1-RAGE interaction., PMID:40348093
For research use only. Not for human or drug use.
