Catalog No.
YHG77601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile209-Pro439
Predicted molecular weight
29.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14314
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibrinogen-like protein 2, pT49, Fibroleukin, FGL2
The Maternal-Fetal Interface Fibrin Deposition and Expression of FGL2 in the Placenta of Preeclampsia and Fetal Growth Restriction., PMID:40388520
Fgl2 regulates FcγRIIB+CD8+ T cell responses during infection., PMID:40197366
Macrophage-derived Fgl2 dampens antitumor immunity through regulation of FcγRIIB+CD8+ T cells in melanoma., PMID:40125553
Fibrinogen-like 2 in tumor-associated macrophage-derived extracellular vesicles shapes an immunosuppressive microenvironment in colorectal liver metastases by promoting tumor stemness and neutrophil extracellular traps formation., PMID:40097065
Novel predictive biomarkers for atonic postpartum hemorrhage as explored by proteomics and metabolomics., PMID:39885444
Role of fibrinogen-like 2 (FGL2) proteins in implantation: Potential implications and mechanism., PMID:39884406
Serum Soluble Fibrinogen-Like Protein 2 Estimates Increased T-Helper 2 Cytokine, Elevated Disease Severity, and Unfavorable Outcomes in Allergic Rhinitis Patients., PMID:39686736
Prognostic significance and gene co-expression network of CD16A and FGL2 in gliomas., PMID:39629005
Proteomic analysis of plasma and duodenal tissue in celiac disease patients reveals potential noninvasive diagnostic biomarkers., PMID:39622892
Exploring the role of neutrophil extracellular traps in neuroblastoma: identification of molecular subtypes and prognostic implications., PMID:39575432
FIBRINOGEN-LIKE PROTEIN 2 PROTECTS THE AGGRAVATION OF HYPERTRIGLYCERIDEMIA ON THE SEVERITY OF HYPERTRIGLYCERIDEMIA ACUTE PANCREATITIS BY REGULATING MACROPHAGES., PMID:39527492
FGL2172-220 peptides improve the antitumor effect of HCMV-IE1mut vaccine against glioblastoma by modulating immunosuppressive cells in the tumor microenvironment., PMID:39508842
FGL2: A new target molecule for coagulation and immune regulation in infectious disease., PMID:39488038
The effect of rs2910686 on ERAP2 expression in IBD and epithelial inflammatory response., PMID:39123229
FGL2 improves experimental colitis related to gut microbiota structure and bile acid metabolism by regulating macrophage autophagy and apoptosis., PMID:39104498
FGL2/FcγRIIB Signalling Mediates Arterial Shear Stress-Mediated Endothelial Cell Apoptosis: Implications for Coronary Artery Bypass Vein Graft Pathogenesis., PMID:39062880
Identification of two key biomarkers CD93 and FGL2 associated with survival of acute myeloid leukaemia by weighted gene co-expression network analysis., PMID:39054581
FGL2 as a predictive biomarker for prognosis and immunotherapy in bladder cancer., PMID:38903931
CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcγRIIB., PMID:38902261
Soluble Fibrinogen-Like Protein 2 Downregulation and Th17/Treg Imbalance in a Taurocholate-Induced Murine Experimental Model of Severe Acute Pancreatitis., PMID:38853390
FGL1 and FGL2: emerging regulators of liver health and disease., PMID:38816776
Proteomic and Cellular Characterization of Omicron Breakthrough Infections and a Third Homologous or Heterologous Boosting Vaccination in a Longitudinal Cohort., PMID:38641227
Tumor and Peritoneum-Associated Macrophage Gene Signature as a Novel Molecular Biomarker in Gastric Cancer., PMID:38612926
Construction and evaluation of endometriosis diagnostic prediction model and immune infiltration based on efferocytosis-related genes., PMID:38370978
Integrated genetic analysis of diabetic complications: Bioinformatics insights into foot ulcers, neuropathy and peripheral artery disease., PMID:38358067
Host transcriptomics and machine learning for secondary bacterial infections in patients with COVID-19: a prospective, observational cohort study., PMID:38310908
Targeted Mass Spectrometry of Longitudinal Patient Sera Reveals LTBP1 as a Potential Surveillance Biomarker for High-Grade Serous Ovarian Carcinoma., PMID:38266179
Analysis of joint protein expression profile in anterior disc displacement of TMJ with or without OA., PMID:38251222
FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models., PMID:38191799
DIA-based quantitative proteomic analysis of porcine endometrium in the peri-implantation phase., PMID:38158016
Fibrinogen-like protein 2 promotes tumor immune suppression by regulating cholesterol metabolism in myeloid-derived suppressor cells., PMID:38056898
Comprehensive analysis of miRNA-mRNA regulatory pairs associated with colorectal cancer and the role in tumor immunity., PMID:38036953
sFgl2 gene-modified MSCs regulate the differentiation of CD4+ T cells in the treatment of autoimmune hepatitis., PMID:37924141
Beyond the Rhythm: In Silico Identification of Key Genes and Therapeutic Targets in Atrial Fibrillation., PMID:37893006
The construction and validation of ECM-related prognosis model in laryngeal squamous cell carcinoma., PMID:37809868
Fibrinogen-like protein 2 regulates macrophage glycolytic reprogramming by directly targeting PKM2 and exacerbates alcoholic liver injury., PMID:37734200
Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain., PMID:37703873
The TIGIT+ T regulatory cells subset associates with nosocomial infection and fatal outcome in COVID-19 patients under mechanical ventilation., PMID:37604833
lncRNA CLRN1-AS1 reduces adhesion ability of human trophoblasts via CXCL10/CXCL11., PMID:37531749
Exploring molecular dynamic indicators associated with reproductive performance of Bos indicus cattle in blood plasma samples through data-independent acquisition mass spectrometry., PMID:37321300
Presence and activity of Fibrinogen like protein 2 in platelets., PMID:37200306
Staphylococcus aureus induces tolerance in human monocytes accompanied with expression changes of cell surface markers., PMID:37063823
FGL2 deficiency alleviates maternal inflammation-induced blood-brain barrier damage by blocking PI3K/NF-κB mediated endothelial oxidative stress., PMID:37051251
Differentiation-related genes in tumor-associated macrophages as potential prognostic biomarkers in non-small cell lung cancer., PMID:36969247
Fibrinogen-like protein 2 promotes proinflammatory macrophage polarization and mitochondrial dysfunction in liver fibrosis., PMID:36878044
Multi-omic approach associates blood methylome with bronchodilator drug response in pediatric asthma., PMID:36796456
Fibrinogen-like protein 2 in inflammatory diseases: A future therapeutic target., PMID:36764282
FGL2-targeting T cells exhibit antitumor effects on glioblastoma and recruit tumor-specific brain-resident memory T cells., PMID:36759517
Identification of key biomarkers and immune infiltration in the thoracic acute aortic dissection by bioinformatics analysis., PMID:36755239
Assessment of Fibrinogen-like 2 (FGL2) in Human Chronic Kidney Disease through Transcriptomics Data Analysis., PMID:36671474
For research use only. Not for human or drug use.
