Catalog No.
YHG76901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu16-Lys290
Predicted molecular weight
32.87 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14249
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endo G, Endonuclease G, mitochondrial, ENDOG
Newly Synthesized PW06 Induced Cell Apoptosis in Human Glioblastoma Multiforme GBM 8401 Cells Through Caspase- and Mitochondria-Dependent Pathways., PMID:40258141
CDK4/6 Inhibitor Can Improve Niraparib Sensitivity and Reverse Acquired Drug Resistance Through Endonuclease G Nuclear Translocation in BRCA Wild-Type Ovarian Cancer: A Vitro Study., PMID:40256809
Inducing Targeted, Caspase-Independent Apoptosis with New Chimeric Proteins for Treatment of Solid Cancers., PMID:40227697
The Role of Metacaspases and Other Proteins Involved in the Apoptosis of Leishmania: Review Article., PMID:40206367
Potential mechanism of dietary palm kernel meal effect on muscle tenderness in Tibetan sheep revealed by proteomics and phosphorylated proteomics., PMID:40068263
Mass Spectrometric Identification of Urinary Biomarkers of Chronic Kidney Disease: A Proteomic-Related Preliminary Report., PMID:40060058
Aflatoxin B1-Induced Apoptosis in Donkey Kidney via EndoG-Mediated Endoplasmic Reticulum Stress., PMID:40005890
Mitochondrial DNA removal is essential for sperm development and activity., PMID:39934414
Apoptotic endonuclease EndoG induces alternative splicing of Caspase-2., PMID:39239896
Yeast EndoG prevents genome instability by degrading extranuclear DNA species., PMID:39227600
The effects of ENDOG on lipid metabolism may be tissue-dependent and may not require its translocation from mitochondria., PMID:39169002
Reply to: The effects of ENDOG on lipid metabolism may be tissue-dependent and may not require its translocation from mitochondria., PMID:39168974
Impact of combined intermittent fasting and high-intensity interval training on apoptosis and atrophy signaling in rat fast- and slow-twitch muscles., PMID:39138135
Naringin Induces ROS-Stimulated G1 Cell-Cycle Arrest and Apoptosis in Nasopharyngeal Carcinoma Cells., PMID:39056589
Caspase-3 promotes oncogene-induced malignant transformation via EndoG-dependent Src-STAT3 phosphorylation., PMID:38977663
TET3 is a positive regulator of mitochondrial respiration in Neuro2A cells., PMID:38227585
The transcription factor AP2 and downstream genes shared by asexual reproduction and zooidal regeneration in the tunicate, Polyandrocarpa misakiensis., PMID:38007002
The biological function of cytoplasm-translocated ENDOG (endonuclease G)., PMID:37889084
Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress., PMID:37794041
The Effect of Cell-Free DNA from Blood Serum of Mice with Metastatic Melanoma on Enhancement of Oncogenic Properties of Melanoma Cells., PMID:37751869
Identifying Profiles of Patients With Uncontrolled Type 2 Diabetes Who Would Benefit From Referral to an Endocrinologist., PMID:37595841
A Novel Isotope-labeled Small Molecule Probe CC12 for Anti-glioma via Suppressing LYN-mediated Progression and Activating Apoptosis Pathways., PMID:37416766
Honokiol attenuates acetaminophen-induced acute liver injury by inhibiting hepatic CYP1A2 activity and improving liver mitochondrial dysfunction., PMID:37265773
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro., PMID:36856879
Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway., PMID:36852641
Ischemic stroke protected by ISO-1 inhibition of apoptosis via mitochondrial pathway., PMID:36797398
Amentoflavone induces caspase-dependent/-independent apoptosis and dysregulates cyclin-dependent kinase-mediated cell cycle in colorectal cancer in vitro and in vivo., PMID:36727907
Muscle fiber characteristics and apoptotic factor differences in beef Longissimus lumborum and Psoas major during early postmortem., PMID:36603399
Mechanism of selective induction of apoptosis of HCT116 tumor cells in circulating blood by riboflavin photochemistry., PMID:36334509
Metformin alleviates HFD-induced oxidative stress in hepatocyte via activating SIRT6/PGC-1α/ENDOG signaling., PMID:36315407
Ectopic endometriosis in the pelvic cavity evokes bladder hypersensitivity via transient receptor potential ankyrin 1 hyperexpression in rats., PMID:36040506
SIRT6 regulates obesity-induced oxidative stress via ENDOG/SOD2 signaling in the heart., PMID:35798905
Novel hybrid pyrrolidinedione-thiazolidinones as potential anticancer agents: Synthesis and biological evaluation., PMID:35533562
Assessment of the Role of Nuclear ENDOG Gene and mtDNA Variations on Paternal Mitochondrial Elimination (PME) in Infertile Men: An Experimental Study., PMID:35477840
Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways., PMID:35436470
Integrative bioinformatics analysis of potential therapeutic targets and immune infiltration characteristics in dilated cardiomyopathy., PMID:35433958
Biallelic Variants in ENDOG Associated with Mitochondrial Myopathy and Multiple mtDNA Deletions., PMID:35326425
Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls., PMID:35024303
Nutrigenomic Studies on the Ameliorative Effect of Enzyme-Digested Phycocyanin in Alzheimer's Disease Model Mice., PMID:34959983
Chemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells., PMID:34845198
Functionalized Tumor-Targeting Nanosheets Exhibiting Fe(II) Overloading and GSH Consumption for Ferroptosis Activation in Liver Tumor., PMID:34448349
Anti-apoptotic and pro-survival effect of exercise training on early aged hypertensive rat cerebral cortex., PMID:34432648
Analysis of Proapoptotic Protein Trafficking to and from Mitochondria., PMID:34096003
Conserved role of ENDOG in promoting autophagy., PMID:33779488
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response., PMID:33473107
Autophagy restricts mitochondrial DNA damage-induced release of ENDOG (endonuclease G) to regulate genome stability., PMID:33465003
Whole-genome sequencing to identify candidate genes for litter size and to uncover the variant function in goats (Capra hircus)., PMID:33276007
DNase I Induces Other Endonucleases in Kidney Tubular Epithelial Cells by Its DNA-Degrading Activity., PMID:33212932
Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE2 pathway in non-small cell lung cancer., PMID:33180744
Hexavalent chromium-induced apoptosis in Hep3B cells is accompanied by calcium overload, mitochondrial damage, and AIF translocation., PMID:33039869
For research use only. Not for human or drug use.
