Catalog No.
YHG76701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His21-Glu220
Predicted molecular weight
23.79 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14246
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADGRE1, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, Adhesion G protein-coupled receptor E1, EMR1, TM7LN3, EMR1 hormone receptor
Lactiplantibacillus Plantarum YDJ-03 and Limosilactobacillus fermentum YDJ-6 Alleviate Metabolic Syndrome in Mice., PMID:40298159
β-Arrestin Condensates Regulate G Protein-Coupled Receptor Function., PMID:40236194
BNIP3-mediated mitophagy in macrophages regulates obesity-induced adipose tissue metaflammation., PMID:40195021
LAMP2-FLOT2 interaction enhances autophagosome-lysosome fusion to protect the septic heart in response to ILC2., PMID:40066518
Overlap of Genomic and Transcriptomic Genes Identified in Familial Eosinophilic Esophagitis., PMID:39914776
Prolyl hydroxylase domain inhibitors prevent kidney crystal formation by suppressing inflammation., PMID:39724472
Macrophage autophagy protects against acute kidney injury by inhibiting renal inflammation through the degradation of TARM1., PMID:39193910
Phenotypic characterisation of bovine alveolar macrophages reveals two major subsets with differential expression of CD163., PMID:38951667
A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets for breast cancer., PMID:38834774
Upregulation of EMR1 (ADGRE1) by Tumor-Associated Macrophages Promotes Colon Cancer Progression by Activating the JAK2/STAT1,3 Signaling Pathway in Tumor Cells., PMID:38673975
Vitamin D3 exacerbates steatosis while calcipotriol inhibits inflammation in non-alcoholic fatty liver disease in Sod1 knockout mice: a comparative study of two forms of vitamin D., PMID:38590249
Progranulin deficiency attenuates tubulointerstitial injury in a mouse unilateral ureteral obstruction model., PMID:38369347
ATG5-regulated CCL2/MCP-1 production in myeloid cells selectively modulates anti-malarial CD4+ Th1 responses., PMID:38368631
6-Formylindolo[3,2-b]carbazole, a potent ligand for the aryl hydrocarbon receptor, attenuates concanavalin-induced hepatitis by limiting T-cell activation and infiltration of proinflammatory CD11b+ Kupffer cells., PMID:38366630
Anti-inflammatory and immunomodulating effects of rilpivirine: Relevance for the therapeutics of chronic liver disease., PMID:37738799
Conventional, high frequency and differential targeted multiplexed spinal cord stimulation in experimental painful diabetic peripheral neuropathy: Pain behavior and role of the central inflammatory balance., PMID:37488684
mthl1, a potential Drosophila homologue of mammalian adhesion GPCRs, is involved in antitumor reactions to injected oncogenic cells in flies., PMID:37459549
Pharmacologic inhibition of HNF4α prevents parenteral nutrition associated cholestasis in mice., PMID:37173326
Central growth hormone action regulates neuroglial and proinflammatory markers in the hypothalamus of male mice., PMID:37030549
EMR1/ADGRE1 Expression in Cancer Cells Upregulated by Tumor-Associated Macrophages Is Related to Poor Prognosis in Colorectal Cancer., PMID:36551877
Integrating network pharmacology and experimental verification to decipher the immunomodulatory effect of Bu-Zhong-Yi-Qi-Tang against poly (I:C)-induced pulmonary inflammation., PMID:36304166
FOXP3+ macrophage represses acute ischemic stroke-induced neural inflammation., PMID:36170234
miR155 deficiency reduces breast tumor burden in the MMTV-PyMT mouse model., PMID:36121133
Microcystin-LR incorporated into colonic cells through probenecid-sensitive transporters leads to upregulated MCP-1 expression induced by JNK activation., PMID:35875256
Administration of nicotinamide mononucleotide improves oocyte quality of obese mice., PMID:35811338
A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in Uterine Corpus Endometrial cancer., PMID:35413679
NUCB2/Nesfatin-1 Reduces Obesogenic Diet Induced Inflammation in Mice Subcutaneous White Adipose Tissue., PMID:35406022
A defective lysophosphatidic acid-autophagy axis increases miscarriage risk by restricting decidual macrophage residence., PMID:35220880
Enantiomer-dependent immunological response to chiral nanoparticles., PMID:35046606
Bioinformatics analysis of an animal model of diet-induced nonalcoholic fatty liver disease with rapid progression., PMID:34775841
NLRC5 Deficiency Deregulates Hepatic Inflammatory Response but Does Not Aggravate Carbon Tetrachloride-Induced Liver Fibrosis., PMID:34712238
Fetuin-A secretion from β-cells leads to accumulation of macrophages in islets, aggravates inflammation and impairs insulin secretion., PMID:34643217
The myeloid cell biomarker EMR1 is ectopically expressed in colon cancer., PMID:34486997
Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation., PMID:34131243
Sugar kelp (Saccharina latissima) inhibits hepatic inflammation and fibrosis in a mouse model of diet-induced nonalcoholic steatohepatitis., PMID:34119629
Immune responses to injury and their links to eye disease., PMID:34051364
Dysfunction in Sertoli cells participates in glucocorticoid-induced impairment of spermatogenesis., PMID:34032349
Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo., PMID:33987714
Effect of Si-Miao-Yong-An decoction on the differentiation of monocytes, macrophages, and regulatory T cells in ApoE-/- mice., PMID:33945857
Identification of vital prognostic genes related to tumor microenvironment in pheochromocytoma and paraganglioma based on weighted gene co-expression network analysis., PMID:33795528
Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization., PMID:33705947
Physical activity modulates mononuclear phagocytes in mammary tissue and inhibits tumor growth in mice., PMID:33552733
Effects of renalase deficiency on liver fibrosis markers in a nonalcoholic steatohepatitis mouse model., PMID:33495844
Aldose reductase regulates doxorubicin-induced immune and inflammatory responses by activating mitochondrial biogenesis., PMID:33482179
Heparanase Deficiency Is Associated with Disruption, Detachment, and Folding of the Retinal Pigment Epithelium., PMID:33372561
Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice., PMID:33294147
Akt1 is involved in tubular apoptosis and inflammatory response during renal ischemia-reperfusion injury., PMID:33247386
TXNIP/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation., PMID:33190588
Network analysis of transcriptomic diversity amongst resident tissue macrophages and dendritic cells in the mouse mononuclear phagocyte system., PMID:33031383