Catalog No.
YHG65901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met213-Trp447
Predicted molecular weight
29.73 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13867
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BMH, BLMH, Bleomycin hydrolase, BH, BLM hydrolase
Assessment of the cytostasis and chromosomal instability potential of myricetin and its chemopreventive effect against bleomycin-induced cyto-genotoxicity., PMID:40244708
Association of GLOD4 with Alzheimer's Disease in Humans and Mice., PMID:39302370
Homocysteine Thiolactone Detoxifying Enzymes and Alzheimer's Disease., PMID:39125665
Nasal Lavage Fluid Proteomics Reveals Potential Biomarkers of Asthma Associated with Disease Control., PMID:38770268
Serum BLMH and CKM as Potential Biomarkers for Predicting Therapeutic Effects of Deep Brain Stimulation in Parkinson's Disease: A Proteomics Study., PMID:38176938
Systematic Analysis of Tumor Stem Cell-related Gene Characteristics to Predict the PD-L1 Immunotherapy and Prognosis of Gastric Cancer., PMID:37936456
Deletion of the Homocysteine Thiolactone Detoxifying Enzyme Bleomycin Hydrolase, in Mice, Causes Memory and Neurological Deficits and Worsens Alzheimer's Disease-Related Behavioral and Biochemical Traits in the 5xFAD Model of Alzheimer's Disease., PMID:37718819
Proteomic analysis reveals mechanisms underlying increased efficacy of bleomycin by photochemical internalization in bladder cancer cells., PMID:37345535
Genetically regulated gene expression and proteins revealed discordant effects., PMID:35604899
The linkage of cell cycle and DNA replication with growth difference in female Chinese tongue sole (Cynoglossus semilaevis): Analysis from transcriptomic study and WGCNA., PMID:33848768
Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen., PMID:33810334
Breast Cancer-Derived Microvesicles Are the Source of Functional Metabolic Enzymes as Potential Targets for Cancer Therapy., PMID:33499132
Bleomycin hydrolase regulates the release of chemokines important for inflammation and wound healing by keratinocytes., PMID:31892708
Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs., PMID:31875550
Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice., PMID:31479664
Paraoxonase 1 Q192R genotype and activity affect homocysteine thiolactone levels in humans., PMID:29782204
New In-Depth Analytical Approach of the Porcine Seminal Plasma Proteome Reveals Potential Fertility Biomarkers., PMID:29411616
Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase., PMID:25333274
Histamine exerts multiple effects on expression of genes associated with epidermal barrier function., PMID:25219105
Chk1 protects against chromatin bridges by constitutively phosphorylating BLM serine 502 to inhibit BLM degradation., PMID:25015292
Methionine-induced hyperhomocysteinemia and bleomycin hydrolase deficiency alter the expression of mouse kidney proteins involved in renal disease., PMID:24913063
Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis., PMID:24633403
Hyperhomocysteinemia and bleomycin hydrolase modulate the expression of mouse brain proteins involved in neurodegeneration., PMID:24496069
The secretome of colon cancer stem cells contains drug-metabolizing enzymes., PMID:23835434
Pharmacogenetic analysis in the treatment of Hodgkin lymphoma., PMID:23323945
Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase., PMID:22227865
Part 2: pharmacogenetic variability in drug transport and phase I anticancer drug metabolism., PMID:21632461
Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin., PMID:21310951
Analysis of association between bleomycin hydrolase and apolipoprotein E polymorphism in Alzheimer's disease., PMID:20198498
Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase., PMID:17391860
Transmission disequilibrium mapping at the serotonin transporter gene (SLC6A4) region in autistic disorder., PMID:11920155
Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease., PMID:11436125
For research use only. Not for human or drug use.
