Catalog No.
YHG59501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val506-Ala743
Predicted molecular weight
28.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13574
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DAGK6, DAG kinase zeta, Diglyceride kinase zeta, DGK-zeta, Diacylglycerol kinase zeta, DGKZ
Ophthalmological manifestations and plasma markers of inflammation in Ebola survivors in post-treatment era., PMID:40301432
Whole Exome Sequencing Identifies Epithelial and Immune Dysfunction-Related Biomarkers in Food Protein-Induced Enterocolitis Syndrome., PMID:39348862
Integration of network pharmacology, lipidomics, and transcriptomics analysis to reveal the mechanisms underlying the amelioration of AKT-induced nonalcoholic fatty liver disease by total flavonoids in vine tea., PMID:38630029
Comparative Analysis of Transcriptome Profiles in Patients with Thromboangiitis Obliterans., PMID:38275601
Base-editing mutagenesis maps alleles to tune human T cell functions., PMID:38093011
Differential expression of diacylglycerol kinase ζ is involved in inferior parietal lobule-related dysfunction in schizophrenia with cognitive impairments., PMID:37479996
The Regulation Network of Glycerolipid Metabolism as Coregulators of Immunotherapy-Related Myocarditis., PMID:37388276
Exome Sequencing Implicates DGKZ , ESRRA , and GXYLT1 for Modulating Granuloma Formation in Crohn Disease., PMID:37347142
Characterization of the Molecular Alterations Induced by the Prolonged Exposure of Normal Colon Mucosa and Colon Cancer Cells to Low-Dose Bisphenol A., PMID:36232920
DGKZ promotes TGFβ signaling pathway and metastasis in triple-negative breast cancer by suppressing lipid raft-dependent endocytosis of TGFβR2., PMID:35115500
Downregulation of Diacylglycerol kinase zeta (DGKZ) suppresses tumorigenesis and progression of cervical cancer by facilitating cell apoptosis and cell cycle arrest., PMID:33926342
Epigenome-wide DNA methylation signature of benzo[a]pyrene exposure and their mediation roles in benzo[a]pyrene-associated lung cancer development., PMID:33887567
Regulation of p53 and NF-κB transactivation activities by DGKζ in catalytic activity-dependent and -independent manners., PMID:33450306
Interplay Between SNX27 and DAG Metabolism in the Control of Trafficking and Signaling at the IS., PMID:32549284
Identification of target genes in neuroinflammation and neurodegeneration after traumatic brain injury in rats., PMID:31875163
Analytical Method for Diacylglycerol Kinase ζ Activity in Cells Using Protein Myristoylation and Liquid Chromatography-Tandem Mass Spectrometry., PMID:31736090
Characterization of α-synuclein N-terminal domain as a novel cellular phosphatidic acid sensor., PMID:31722116
Knockdown of DEAD-box RNA helicase DDX5 selectively attenuates serine 311 phosphorylation of NF-κB p65 subunit and expression level of anti-apoptotic factor Bcl-2., PMID:31626956
DGKζ Plays Crucial Roles in the Proliferation and Tumorigenicity of Human glioblastoma., PMID:31523189
Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms., PMID:31481522
DzMab-1: Anti-Human Diacylglycerol Kinaseζ Monoclonal Antibody for Immunocytochemistry., PMID:31403910
Epitope Mapping of Anti-Diacylglycerol Kinase Zeta Monoclonal Antibody DzMab-1 for Immunohistochemical Analyses., PMID:31355694
Knockdown of diacylglycerol kinase zeta (DGKZ) induces apoptosis and G2/M phase arrest in human acute myeloid leukemia HL-60 cells through MAPK/survivin/caspase pathway., PMID:31288898
Epitope Mapping of Anti-Diacylglycerol Kinase ζ Monoclonal Antibody for the Detection of T Cells by Immunohistochemical Analyses., PMID:31112065
Expression analysis and genotyping of DGKZ: a GWAS-derived risk gene for schizophrenia., PMID:31087244
DGKZ Acts as a Potential Oncogene in Osteosarcoma Proliferation Through Its Possible Interaction With ERK1/2 and MYC Pathway., PMID:30662872
Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review., PMID:29910734
SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes., PMID:29180720
Dysregulated miR34a/diacylglycerol kinase ζ interaction enhances T-cell activation in acquired aplastic anemia., PMID:28008152
Diacylglycerol kinase ζ limits the polarized recruitment of diacylglycerol-enriched organelles to the immune synapse in T cells., PMID:27999176
Diacylglycerol kinases in cancer., PMID:27697466
African-specific variability in the acetylcholine muscarinic receptor M4: association with cocaine and heroin addiction., PMID:27269905
The effect of HMGB1 on the clinicopathological and prognostic features of non-small cell lung cancer., PMID:26840258
Reciprocal regulation of p53 and NF-κB by diacylglycerol kinase ζ., PMID:26521214
Loss of Diacylglycerol Kinase-Ζ Inhibits Cell Proliferation and Survival in Human Gliomas., PMID:26452358
Redundant and specialized roles for diacylglycerol kinases α and ζ in the control of T cell functions., PMID:25921290
RNA sequencing identifies upregulated kyphoscoliosis peptidase and phosphatidic acid signaling pathways in muscle hypertrophy generated by transgenic expression of myostatin propeptide., PMID:25860951
Downregulation of diacylglycerol kinase ζ enhances activation of cytokine-induced NF-κB signaling pathway., PMID:25450975
Influence of DGKH variants on amygdala volume in patients with bipolar affective disorder and schizophrenia., PMID:24958494
DNA methylation status is more reliable than gene expression at detecting cancer in prostate biopsy., PMID:24937670
Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion., PMID:24646293
Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation., PMID:23723068
Tyrosinase: a central regulatory protein for cutaneous pigmentation., PMID:23187110
Diacylglycerol kinase regulates tyrosinase expression and function in human melanocytes., PMID:22895365
Negative feedback regulation of Gq signaling by protein kinase C is disrupted by diacylglycerol kinase ζ in COS-7 cells., PMID:22197823
Interaction of nucleosome assembly proteins abolishes nuclear localization of DGKζ by attenuating its association with importins., PMID:21996351
Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse., PMID:21937721
Translocation dynamics of sorting nexin 27 in activated T cells., PMID:21303929
Integrated genomic profiling identifies loss of chromosome 11p impacting transcriptomic activity in aggressive pituitary PRL tumors., PMID:21251114
Endocannabinoids and diacylglycerol kinase activity., PMID:21194521
For research use only. Not for human or drug use.
