Catalog No.
YHG56301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val175-Leu387
Predicted molecular weight
26.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13505
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mitochondrial outer membrane import complex protein 1, MTX, MTXN, Metaxin-1, MTX1
Multi-Omics Analysis Links Mitochondrial-Related Genes to Idiopathic Pulmonary Fibrosis and In Vivo Transcriptome Validation., PMID:39952317
Integrated Mendelian Randomization and Single-Cell Transcriptomics Analysis Identifies Critical Blood Biomarkers and Potential Mechanisms in Epilepsy., PMID:39753851
Structure-Function Relationship of a Novel MTX-like Peptide (MTX1) Isolated and Characterized from the Venom of the Scorpion Maurus palmatus., PMID:39408804
Single-cell and genome-wide Mendelian randomization identifies causative genes for gout., PMID:38831441
Polygenic risk score trend and new variants on chromosome 1 are associated with male gout in genome-wide association study., PMID:36221101
Interferon gamma upregulates the cytokine receptors IFNGR1 and TNFRSF1A in HT-29-MTX E12 cells., PMID:35653895
Ultrastructural and proteomic profiling of mitochondria-associated endoplasmic reticulum membranes reveal aging signatures in striated muscle., PMID:35368021
Pleiotropic Effects of Functional MUC1 Variants on Cardiometabolic, Renal, and Hematological Traits in the Taiwanese Population., PMID:34638981
AREL1 E3 ubiquitin ligase inhibits TNF-induced necroptosis via the ubiquitination of MTX2., PMID:34584540
Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy., PMID:34421355
Variants in urate transporters, ADH1B, GCKR and MEPE genes associate with transition from asymptomatic hyperuricaemia to gout: results of the first gout versus asymptomatic hyperuricaemia GWAS in Caucasians using data from the UK Biobank., PMID:33832965
Chromatin architecture reveals cell type-specific target genes for kidney disease risk variants., PMID:33627123
Metaxins are core components of mitochondrial transport adaptor complexes., PMID:33397950
Loss of MTX2 causes mandibuloacral dysplasia and links mitochondrial dysfunction to altered nuclear morphology., PMID:32917887
The plasma peptides of sepsis., PMID:32636717
Synergistic Effect of Transient Receptor Potential Antagonist and Amiloride against Maitotoxin Induced Calcium Increase and Cytotoxicity in Human Neuronal Stem Cells., PMID:29733572
Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway., PMID:29149599
The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death., PMID:27845183
Evolution and structural organization of the mitochondrial contact site (MICOS) complex and the mitochondrial intermembrane space bridging (MIB) complex., PMID:26477565
Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2., PMID:26016997
Genetic variation and gastric cancer risk: a field synopsis and meta-analysis., PMID:25731870
Metaxins 1 and 2, two proteins of the mitochondrial protein sorting and assembly machinery, are essential for Bak activation during TNF alpha triggered apoptosis., PMID:24794530
Mtx toxins from Lysinibacillus sphaericus enhance mosquitocidal cry-toxin activity and suppress cry-resistance in Culex quinquefasciatus., PMID:24144574
Expression of adipokine and lipid metabolism genes in adipose tissue of dairy cows differing in a female fertility quantitative trait locus., PMID:24119802
Identification and characterization of two novel toxins expressed by the lethal honey bee pathogen Paenibacillus larvae, the causative agent of American foulbrood., PMID:23992535
Identification of mosquito larvicidal bacterial strains isolated from north Sinai in Egypt., PMID:22280528
Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes., PMID:22252321
Homozygosity for the MTX1 c.184T>A (p.S63T) alteration modifies the age of onset in GBA-associated Parkinson's disease., PMID:21837367
Identification of recombinant alleles using quantitative real-time PCR implications for Gaucher disease., PMID:21704274
Lysinibacillus sphaericus S-layer protein toxicity against Culex quinquefasciatus., PMID:21671091
Metaxin deficiency alters mitochondrial membrane permeability and leads to resistance to TNF-induced cell killing., PMID:21088703
Properties and applied use of the mosquitocidal bacterium, Bacillus sphaericus., PMID:28883761
Lactation stage-dependent expression of transporters in rat whole mammary gland and primary mammary epithelial organoids., PMID:19702690
A new agent for tumour necrosis factor-alpha inhibition: In vitro effects of dipyridamole in Crohn's disease., PMID:19452347
Detection of Bacillus sphaericus mosquitocidal toxin genes by multiplex colony PCR., PMID:19295654
Bacillus sphaericus Mtx1 and Mtx2 toxins co-expressed in Escherichia coli are synergistic against Aedes aegypti larvae., PMID:19082531
Mtx toxins synergize Bacillus sphaericus and Cry11Aa against susceptible and insecticide-resistant Culex quinquefasciatus larvae., PMID:17704274
[The synergism between Mtx1 from Bacillus sphaericus and Cyt1 Aa from Bacillus thuringiensis to Culex quinquefasciatus]., PMID:17672305
The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11., PMID:17624330
Conserved roles of Sam50 and metaxins in VDAC biogenesis., PMID:17510655
Lack of cross-resistance to Mtx1 from Bacillus sphaericus in B. sphaericus-resistant Culex quinquefasciatus (Diptera: Culicidae)., PMID:17103380
Proteolytic stability of insecticidal toxins expressed in recombinant bacilli., PMID:17098916
The yolk syncytial layer regulates myocardial migration by influencing extracellular matrix assembly in zebrafish., PMID:17008449
Cytolytic toxin Cyt1Aa of Bacillus thuringiensis synergizes the mosquitocidal toxin Mtx1 of Bacillus sphaericus., PMID:16960378
Mosquitocidal toxin from Bacillus sphaericus induces stronger delayed effects than binary toxin on Culex quinquefasciatus (Diptera: Culicidae)., PMID:16892631
Differential gene expression in lymphocytes from malnourished children., PMID:16731013
Partial restoration of antibacterial activity of the protein encoded by a cryptic open reading frame (cyt1Ca) from Bacillus thuringiensis subsp. israelensis by site-directed mutagenesis., PMID:16159771
Characterization of the cDNA and amino acid sequences of Xenopus Metaxin 3, and relationship to Xenopus Metaxins 1 and 2., PMID:16147884
Rat reduced-folate carrier-1 is localized basolaterally in MDCK kidney epithelial cells and contributes to the secretory transport of methotrexate and fluoresceinated methotrexate., PMID:15846510
Cloning and characterization of a mosquito larvicidal toxin produced during vegetative stage of Bacillus sphaericus 2297., PMID:15297911
For research use only. Not for human or drug use.
