Catalog No.
YHG53501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro440-Gly680
Predicted molecular weight
28.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13443
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Disintegrin and metalloproteinase domain-containing protein 9, Meltrin-gamma, ADAM9, MDC9, MLTNG, ADAM 9, Metalloprotease/disintegrin/cysteine-rich protein 9, Cellular disintegrin-related protein, KIAA0021, MCMP, Myeloma cell metalloproteinase
Potential Influence of ADAM9 Genetic Variants and Expression Levels on the EGFR Mutation Status and Disease Progression in Patients with Lung Adenocarcinoma., PMID:40429751
ADAM9 Genetic Variants and Their Role in Modulating Enzyme Activity in Diabetes and Metabolic Traits., PMID:40330740
Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer's disease., PMID:40313591
Differential roles of the ADAM9/NF-κB and the ADAM9/STAT3 feedback loops in HIV-1 Tat-induced microglial inflammatory response and subsequent neuronal apoptosis., PMID:40203953
Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma., PMID:40113769
ADAM9 mediates Cisplatin resistance in gastric cancer cells through DNA damage response pathway., PMID:40108033
NACC1 accelerates the progression of AML by regulating the ADAM9/PI3K/AKT axis., PMID:39898241
Matrix Metalloproteinases, Tissue Inhibitors of Metalloproteinases, and Their Ratios in Women with Polycystic Ovary Syndrome and Healthy Controls., PMID:39796177
A disintegrin and metallopeptidase domain (ADAM) 12, ADAM 17 mRNA and ADAM10 protein hold potential as biomarkers for detection of early gastric cancer., PMID:39755747
MLL1 promotes placental trophoblast ferroptosis and aggravates preeclampsia symptoms through epigenetic regulation of RBM15/TRIM72/ADAM9 axis., PMID:39709463
Genetic variants of ADAM9 as potential predictors for biochemical recurrence in prostate cancer patients after receiving a radical prostatectomy., PMID:39628685
Circ-ADAM9 Knockdown Reduces Insulin Resistance and Placental Injury in Diabetic Mice via MAPK Pathway Inactivation., PMID:39575501
An integrative proteotranscriptomics approach reveals new ADAM9 substrates and downstream pathways., PMID:39574690
Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage., PMID:39563331
A pan-cancer study of ADAM9's immunological function and prognostic value particularly in liver cancer., PMID:39505907
Deciphering the oncogenic potential of ADAM9 in hepatocellular carcinoma through bioinformatics and experimental approaches., PMID:39488509
Overexpression of a disintegrin and metalloproteinase 9 (ADAM9) in relation to poor prognosis of patients with oral squamous cell carcinoma., PMID:39441449
Unraveling the role of ADAMs in clinical heterogeneity and the immune microenvironment of hepatocellular carcinoma: insights from single-cell, spatial transcriptomics, and bulk RNA sequencing., PMID:39346916
Hypoxia Promotes the Expression of ADAM9 by Tubular Epithelial Cells, Which Enhances Transforming Growth Factor β1 Activation and Promotes Tissue Fibrosis in Patients With Lupus Nephritis., PMID:39279154
Association of ADAM family members with proliferation signaling and disease progression in multiple myeloma., PMID:39261477
ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing., PMID:39229132
Hepatic Amyloid Beta-42-Metabolizing Proteins in Liver Steatosis and Metabolic Dysfunction-Associated Steatohepatitis., PMID:39201455
Sevoflurane Affects Myocardial Autophagy Levels After Myocardial Ischemia Reperfusion Injury via the microRNA-542-3p/ADAM9 Axis., PMID:39126581
LncRNA NEAT1 targets miR-125/ADAM9 mediated NF-κB pathway in inflammatory response of rosacea., PMID:38988131
An Antibody of the Secreted Isoform of Disintegrin and Metalloprotease 9 (sADAM9) Inhibits Epithelial-Mesenchymal Transition and Migration of Prostate Cancer Cell Lines., PMID:38928352
Identification of coagulation diagnostic biomarkers related to the severity of spinal cord injury., PMID:38908081
Four Unique Genetic Variants in Three Genes Account for 62.7% of Early-Onset Severe Retinal Dystrophy in Chile: Diagnostic and Therapeutic Consequences., PMID:38892339
Whole genome sequencing of HER2-positive metastatic extramammary Paget's disease: a case report., PMID:38831459
Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein., PMID:38777146
ADAM9 promotes type I interferon-mediated innate immunity during encephalomyocarditis virus infection., PMID:38755212
Lipoxin A4 ameliorates knee osteoarthritis progression in rats by antagonizing ferroptosis through activation of the ESR2/LPAR3/Nrf2 axis in synovial fibroblast-like synoviocytes., PMID:38754271
ADAM9 drives the immunosuppressive microenvironment by cholesterol biosynthesis-mediated activation of IL6-STAT3 signaling for lung tumor progression., PMID:38726266
Exploring Potential Biomarkers in Oesophageal Cancer: A Comprehensive Analysis., PMID:38673838
Identification of Novel Cuproptosis-Related Genes Mediating the Prognosis and Immune Microenvironment in Cholangiocarcinoma., PMID:38613350
CAPN2-responsive mesoporous silica nanoparticles: A promising nanocarrier for targeted therapy of pancreatic cancer., PMID:38589004
Exploring the oncogenic and tumor-suppressive roles of Circ-ADAM9 in cancer., PMID:38537524
A Disintegrin and metalloproteinase carves T cell abnormalities and pathogenesis in systemic lupus erythematosus., PMID:38458301
Therapeutic restoration of miR-126-3p as a multi-targeted strategy to modulate the liver tumor microenvironment., PMID:38358374
Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy., PMID:38267627
ADAM9 deubiquitination induced by USP22 suppresses proliferation, migration, invasion, and epithelial-mesenchymal transition of trophoblast cells in preeclampsia., PMID:38176298
Hsa_circ_0001583 fuels bladder cancer metastasis by promoting staphylococcal nuclease and tudor domain containing 1-mediated MicroRNA decay., PMID:38176295
Circ_0061140 Potentiates Clear Cell Renal Cell Carcinoma Progression Via the MicroRNA-126-5p/ADAM9 Axis., PMID:38062234
Licochalcone A Inhibits Proliferation and Metastasis of Colon Cancer by Regulating miR-1270/ADAM9/Akt/NF-κB axis., PMID:38033851
Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair., PMID:37918552
Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans., PMID:37728486
A disintegrin and metalloproteinase domain 9 facilitates SARS-CoV-2 entry into cells with low ACE2 expression., PMID:37713503
A Metalloproteinase Cocktail from the Venom of Protobothrops flavoviridis Cleaves Amyloid Beta Peptides at the α-Cleavage Site., PMID:37624257
Preclinical Assessment of ADAM9-Responsive Mesoporous Silica Nanoparticles for the Treatment of Pancreatic Cancer., PMID:37445886
The role of BHLHE40 in clinical features and prognosis value of PDAC by comprehensive analysis and in vitro validation., PMID:37377917
Functional characteristics of DNA N6-methyladenine modification based on long-read sequencing in pancreatic cancer., PMID:37279592
For research use only. Not for human or drug use.
