Catalog No.
YHG51901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn183-Lys452
Predicted molecular weight
33.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13418
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ILK, ILK2, ILK1, ILK-2, ILK-1, 59 kDa serine/threonine-protein kinase, Beta-integrin-linked kinase, p59ILK, Integrin-linked protein kinase
Cigarette Smoke-Induced PPAR Signaling Dysregulation Accelerates Alzheimer's Disease Pathogenesis and Cognitive Decline in 5xFAD Mice., PMID:40513939
One-pot, chemoselective desulfurative functionalization of cysteine containing peptides using pyridinium salts., PMID:40510019
Roles of focal adhesion proteins in obesity related metabolic syndrome., PMID:40505834
Characterization of immune features and discovery of potential biomarkers for ankylosing spondylitis using deep plasma proteomics., PMID:40436140
A meta-analysis to re-evaluate the sensitivity and specificity of FMDV NSP ELISA tests., PMID:40424643
The role of the extracellular matrix protein SPOCK2 for bone physiology and hematopoiesis., PMID:40403823
Exploring focal adhesion data: dynamic parameter extraction from FRAP and FLAP experiments using chemical master equation., PMID:40396124
Interaction of Serratia proteamaculans with Integrins Activates Invasion-Promoting Signaling Pathways., PMID:40362195
Artesunate Inhibits Metastatic Potential in Cisplatin-Resistant Bladder Cancer Cells by Altering Integrins., PMID:40277897
[A Case of Dengue Fever Presenting with Fever and Atypical Skin Rash and A Literature Review]., PMID:40277271
Integrin linked kinase and threonine tyrosine kinase modulate TCR signaling., PMID:40274929
Plasma Proteomic Profiling Reveals ITGA2B as A Key Regulator of Heart Health in High-altitude Settlers., PMID:40198259
The biological function of integrin-linked kinase on bone formation., PMID:40171447
Identification of a Novel Antagonist of BRS-3 from Natural Products and Its Protective Effects Against H2O2-Induced Cardiomyocyte Injury., PMID:40141387
Integrin-Linked Kinase (ILK) Promotes Mitochondrial Dysfunction by Decreasing CPT1A Expression in a Folic Acid-Based Model of Kidney Disease., PMID:40076489
MCP-1 promotes ILK phosphorylation at Ser246 during endometriosis development and affects the pregnancy outcome., PMID:40037802
PARP-2 acts on ILK signaling and pharmacological targeting of PARP-2 ameliorate endometriosis in a mouse model., PMID:40036901
β-arrestin 1 and integrin-linked kinase interact in epidermal keratinocytes and regulate cell motility., PMID:39945280
miR-758-3p Interferes with Neuronal Apoptosis in Cerebral Ischemia-Reperfusion by Inhibiting ILK., PMID:39937418
Bioinformatics analysis combined with experimental validation reveals the biological role of the ILK gene in prostate cancer., PMID:39890647
DGCR2 targeting affibody molecules for delivery of drugs and imaging reagents to human beta cells., PMID:39747317
Platelet stimulation-regulated expression of ILK and ITGB3 contributes to intrahepatic cholangiocarcinoma progression through FAK/PI3K/AKT pathway activation., PMID:39725790
Emergence of the cell-matrix adhesion element ILK as a player in glioblastoma cell plasticity., PMID:39689679
Prognostic Value of PD-L1, BAP-1 and ILK in Pleural Mesothelioma., PMID:39685780
Expression Profiles of Integrin-Linked Kinase, Vascular Endothelial Growth Factor A, and Ephrin Type-A Receptor 2 in Colorectal Cancer Lymph Nodes., PMID:39525153
Neutrophil extracellular traps with low concentrations induce proliferation and migration of human fibroblasts via activating CCDC25/ILK/PI3K/AKT pathway., PMID:39522234
OSU-T315 overcomes immunosuppression in triple-negative breast cancer by targeting the ILK/NF-κB signaling pathway to enhance immunotherapeutic efficacy., PMID:39515039
TMEM182 inhibits myocardial differentiation of human iPS cells by maintaining the activated state of Wnt/β-catenin signaling through an increase in ILK expression., PMID:39512841
RNF19A inhibits bladder cancer progression by regulating ILK ubiquitination and inactivating the AKT/mTOR signalling pathway., PMID:39508245
Optimized method for fluorine-18 radiolabeling of Affibody molecules using RESCA., PMID:39460878
A microfluidic in vitro method predicting the fate of peptide drugs after subcutaneous administration., PMID:39454976
In Silico Modeling of Fabry Disease Pathophysiology for the Identification of Early Cellular Damage Biomarker Candidates., PMID:39408658
Integrins linked kinase and focal adhesion kinase as the key signaling mediators of vascular mimicry in metastatic breast tumor cells., PMID:39354559
Hexosaminidase B-driven cancer cell-macrophage co-dependency promotes glycolysis addiction and tumorigenesis in glioblastoma., PMID:39353936
Replicative Endothelial Cell Senescence May Lead to Endothelial Dysfunction by Increasing the BH2/BH4 Ratio Induced by Oxidative Stress, Reducing BH4 Availability, and Decreasing the Expression of eNOS., PMID:39337378
An ILK/STAT3 pathway controls glioblastoma stem cell plasticity., PMID:39326421
Oral Administration of Probiotic Bifidobacterium breve Ameliorates Tonic-Clonic Seizure in a Pentylenetetrazole-Induced Kindling Mouse Model via Integrin-Linked Kinase Signaling., PMID:39273208
Inhibition of the ITGB1 gene attenuates crystalline silica-induced pulmonary fibrosis via epithelial-mesenchymal transformation., PMID:39258668
FRAP analysis of peptide diffusion in extracellular matrix mimetic hydrogels as an in vitro model for subcutaneous injection., PMID:39179009
Integrin-linked kinase control dental pulp stem cell senescence via the mTOR signaling pathway., PMID:39169713
PrPC controls epithelial-to-mesenchymal transition in EGFR-mutated NSCLC: implications for TKI resistance and patient follow-up., PMID:39147880
Icariin protects against acute graft-versus-host disease while preserving graft-versus-leukemia activity after allogeneic hematopoietic stem cell transplantation., PMID:39067193
The Evolving Role of Bruton's Tyrosine Kinase Inhibitors in B Cell Lymphomas., PMID:39062757
Human microglial cells as a therapeutic target in a neurodevelopmental disease model., PMID:39059378
The Role of NOTCH Pathway Genes in the Inherited Susceptibility to Aortic Stenosis., PMID:39057646
MCP-1 exerts the inflammatory response via ILK activation during endometriosis pathogenesis., PMID:39004271
Development and validation of LC-MS/MS methods for the pharmacokinetic assessment of the PROTACs bavdeglutamide (ARV-110) and vepdegestrant (ARV-471)., PMID:38996751
Integrin-Linked Kinase in the Development of Gastric Tumors Induced by Helicobacter pylori: Regulation and Prevention Potential., PMID:38951739
Clinical efficacy of SARS-CoV-2 Omicron-neutralizing antibodies in immunoglobulin preparations for the treatment of agammaglobulinemia in patients with primary antibody deficiency., PMID:38884390
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway., PMID:38823175
For research use only. Not for human or drug use.
