Catalog No.
YHG49901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu24-Cys162
Predicted molecular weight
18.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13361
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAGP2, MAGP-2, MFAP-5, MP25, Microfibril-associated glycoprotein 2, MFAP5, Microfibrillar-associated protein 5
Microfibril-Associated Protein 5 Contributes to the Elastic Fiber Abnormalities in Aged Skin., PMID:40268468
Increased Sirtuin 6 Activity in Tumor Cells Can Prompt CD4-Positive T-Cell Differentiation Into Regulatory T Cells and Impede Immune Surveillance in the Microenvironment., PMID:40162112
Molecular Markers of Occult Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients., PMID:40018925
Proteins and pathways involved in inflammation are longitudinally associated with total body bone mineral density among primarily Hispanic overweight/obese adolescents and young adults., PMID:39808688
Proteomic Analysis of Mesenchymal Stem Cell-derived Exosomes in Psoriasis., PMID:39779548
MFAP5 inhibits the malignant progression of endometrial cancer cells in vitro., PMID:39759103
Identification and validation of the diagnostic biomarker MFAP5 for CAVD with type 2 diabetes by bioinformatics analysis., PMID:39749331
Shared Gene Expression Dysregulation Across Subtypes of Sanfilippo and Morquio Diseases: The Role of PFN1 in Regulating Glycosaminoglycan Levels., PMID:39735993
High-resolution subtyping of fibroblasts in gastric cancer reveals diversity among fibroblast subsets and an association between the MFAP5-fibroblast subset and immunotherapy., PMID:39524442
Upregulation of MFAP5 Enhances COL1A1 Expression, Promoting Epithelial-Mesenchymal Transition in Gastric Cancer Cells., PMID:39463228
Single-cell RNA sequencing identifies inherent abnormalities of adipose-derived stem cells from nonlesional sites of patients with localized scleroderma., PMID:39215271
Effects of Gene Alternative Splicing Events on Resistance to Cryptocaryonosis of Large Yellow Croaker (Larimichthys crocea)., PMID:38969905
Multicompartment Polyion Complex Micelles Based on Triblock Polypept(o)ides Mediate Efficient siRNA Delivery to Cancer-Associated Fibroblasts for Antistromal Therapy of Hepatocellular Carcinoma., PMID:38958110
Loci cg06256735 and cg15815843 in the MFAP5 gene regulatory regions are hypomethylated in varicose veins apparently due to active demethylation., PMID:38743016
The insulin-like growth factor binding protein-microfibrillar associated protein-sterol regulatory element binding protein axis regulates fibroblast-myofibroblast transition and cardiac fibrosis., PMID:38586912
MFAP5 Strengthened the Stem Cell Features of Non-small Cell Lung Cancer Cells by Regulating the FBW/Sox9 Axis., PMID:38415489
MAGP2 promotes osteogenic differentiation during fracture healing through its crosstalk with the β-catenin pathway., PMID:38348695
Plasma fibroblast activation protein is decreased in acute heart failure despite cardiac tissue upregulation., PMID:38297310
CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma., PMID:38186580
Identification and validation of feature genes associated with M1 macrophages in preeclampsia., PMID:38048229
Extracellular matrix analysis of fibrosis: A step towards tissue engineering for urethral stricture disease., PMID:38032942
MFAP5 variant-induced multiple giant thoracic aortic aneurysm., PMID:38031457
Tricellulin, α-Catenin and Microfibrillar-Associated Protein 5 Exhibit Concomitantly Altered Immunosignals along with Vascular, Extracellular and Cytoskeletal Elements after Experimental Focal Cerebral Ischemia., PMID:37569268
A comprehensive analysis of biomarkers associated with synovitis and chondrocyte apoptosis in osteoarthritis., PMID:37545537
Key Molecules in Bladder Cancer Affect Patient Prognosis and Immunotherapy Efficacy: Further Exploration for CNTN1 and EMP1., PMID:37437228
Interactions between MFAP5 + fibroblasts and tumor-infiltrating myeloid cells shape the malignant microenvironment of colorectal cancer., PMID:37344903
Microfibril-associated protein 5 and the regulation of skin scar formation., PMID:37253753
Cancer-associated fibroblasts in the invasive tumour front promote the metastasis of oral squamous cell carcinoma through MFAP5 upregulation., PMID:37217152
Targeting MFAP5 in cancer-associated fibroblasts sensitizes pancreatic cancer to PD-L1-based immunochemotherapy via remodeling the matrix., PMID:37156839
Microfibrillar-associated protein 5 suppresses adipogenesis by inhibiting essential coactivator of PPARγ., PMID:37020143
Microfibril-Associated Glycoprotein-2 Promoted Fracture Healing via Integrin αvβ3/PTK2/AKT Signaling., PMID:36934797
Angiotensin receptor blockers retard the progression and fibrosis via inhibiting the viability of AGTR1+ CAFs in intrahepatic cholangiocarcinoma., PMID:36855786
Comparative Hypothalamic Transcriptome Analysis Reveals Crucial mRNAs, lncRNAs, and circRNAs Affecting Litter Size in Goats., PMID:36833370
Microfibril Associated Protein 5 (MFAP5) Is Related to Survival of Ovarian Cancer Patients but Not Useful as a Prognostic Biomarker., PMID:36555638
High expression of COL6A1 predicts poor prognosis and response to immunotherapy in bladder cancer., PMID:36474424
Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype., PMID:36167601
Microfiber-associated protein 5 (MFAP5): A promising approach to discover new biomarkers for heart failure and cardiac remodeling., PMID:35810921
Proteomic Analyses Identify Therapeutic Targets in Hepatocellular Carcinoma., PMID:35433463
High glucose stimulating ECM remodeling and an inflammatory phenotype in the IPFP via upregulation of MFAP5 expression., PMID:35240498
MAGP2 induces tumor progression by enhancing uPAR-mediated cell proliferation., PMID:34915136
Microfibrillar-associated protein 5 regulates osteogenic differentiation by modulating the Wnt/β-catenin and AMPK signaling pathways., PMID:34865619
Levofloxacin exerts broad-spectrum anticancer activity via regulation of THBS1, LAPTM5, SRD5A3, MFAP5 and P4HA1., PMID:34419964
A novel mechanism driving poor-prognostic gastric cancer: overexpression of the transcription factor Krüppel-like factor 16 promotes growth and metastasis of gastric cancer through regulating the Notch pathway., PMID:34249424
Atorvastatin Augments Gemcitabine-Mediated Anti-Cancer Effects by Inhibiting Yes-Associated Protein in Human Cholangiocarcinoma Cells., PMID:33066548
Reduced MFAP5 expression in stroma of gallbladder adenocarcinoma and its potential diagnostic utility., PMID:32895766
Prognostic and clinicopathological values of tissue expression of MFAP5 and ITM2A in triple-negative breast cancer: an immunohistochemical study., PMID:32774133
Molecular structure and function of microfibrillar-associated proteins in skeletal and metabolic disorders and cancers., PMID:32572962
CAFs-derived MFAP5 promotes bladder cancer malignant behavior through NOTCH2/HEY1 signaling., PMID:32293074
Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma., PMID:32047565
For research use only. Not for human or drug use.
