Catalog No.
YHG49001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg77-Gly374
Predicted molecular weight
35.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13332
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
R-PTP-S, PTPRS, Receptor-type tyrosine-protein phosphatase S, R-PTP-sigma, Receptor-type tyrosine-protein phosphatase sigma
Genome-wide transcriptomic response of whole blood to radiation., PMID:40473848
Genetic insight into lung neuroendocrine tumors: Notch and Wnt signaling pathways as potential targets., PMID:40361150
Molecular heterogeneity of CD30+ peripheral T-cell lymphoma with prognostic significance and therapeutic implications: a retrospective multi-centre study., PMID:40215750
Papillary Tumor of the Pineal Region Identified by DNA Methylation Leads to the Incidental Finding of Germline Mutation PTEN G132D Associated with PTEN Hamartoma Tumor Syndrome: A Case Report and Systematic Review., PMID:40136376
Reduced PTPRS expression promotes epithelial-mesenchymal transition of Schwann cells in NF1-related plexiform neurofibromas., PMID:39094827
The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex., PMID:38977849
PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's disease., PMID:38926456
Calycosin promotes axon growth by inhibiting PTPRS and alleviates spinal cord injury., PMID:38904846
Gene-gene interaction analysis for age at onset of bipolar disorder in a Korean population., PMID:38834091
PTPRS is a novel marker for early tau pathology and synaptic integrity in Alzheimer's disease., PMID:38766183
Mass Spectrometry-Based Proteomics Analysis Unveils PTPRS Inhibits Proliferation and Inflammatory Response of Keratinocytes in Psoriasis., PMID:38739342
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma., PMID:38517048
Chronic TNF exposure induces glucocorticoid-like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia., PMID:38459711
Genome-Wide Association Studies of 3 Distinct Recovery Phenotypes in Mild Ischemic Stroke., PMID:38181310
Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit., PMID:37591863
Exonic mutations in cell-cell adhesion may contribute to CADASIL-related CSVD pathology., PMID:37422595
Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance., PMID:37374154
Quantitative Evaluation of Stem-like Markers of Human Glioblastoma Using Single-Cell RNA Sequencing Datasets., PMID:36900348
Fisetin, a dietary flavonoid, increases the sensitivity of chemoresistant head and neck carcinoma cells to cisplatin possibly through HSP90AA1/IL-17 pathway., PMID:36631292
FOLFOXIRI Resistance Induction and Characterization in Human Colorectal Cancer Cells., PMID:36230735
High expression of protein tyrosine phosphatase receptor S (PTPRS) is an independent prognostic marker for cholangiocarcinoma., PMID:35991009
Inhibition of CSPG receptor PTPσ promotes migration of newly born neuroblasts, axonal sprouting, and recovery from stroke., PMID:35905716
Distinct transcriptomic profile of small arteries of hypertensive patients with chronic kidney disease identified miR-338-3p targeting GPX3 and PTPRS., PMID:35703228
Finding New Ways How to Control BACE1., PMID:35305135
Terminalin from African Mango (Irvingia gabonensis) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases., PMID:35204821
LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain., PMID:34966732
Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development., PMID:34863978
Identification and validation of tissue or ctDNA PTPRD phosphatase domain deleterious mutations as prognostic and predictive biomarkers for immune checkpoint inhibitors in non-squamous NSCLC., PMID:34615542
Perineuronal Net Receptor PTPσ Regulates Retention of Memories., PMID:34366821
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma., PMID:34154646
Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR., PMID:33656439
Proteoglycans regulate protein tyrosine phosphatase receptor σ organization on hematopoietic stem/progenitor cells., PMID:33515635
Chondroitinase and Antidepressants Promote Plasticity by Releasing TRKB from Dephosphorylating Control of PTPσ in Parvalbumin Neurons., PMID:33293360
Protein Tyrosine Phosphatase Receptor S Acts as a Metastatic Suppressor in Malignant Peripheral Nerve Sheath Tumor via Profilin 1-Induced Epithelial-Mesenchymal Transition., PMID:33163494
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p., PMID:33151000
Genetic characteristics of gastric-type mucinous carcinoma of the uterine cervix., PMID:32641744
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal., PMID:32637608
PTPσ Knockdown in Lampreys Impairs Reticulospinal Axon Regeneration and Neuronal Survival After Spinal Cord Injury., PMID:32265663
Presynaptic PTPσ regulates postsynaptic NMDA receptor function through direct adhesion-independent mechanisms., PMID:32142410
LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ., PMID:31995730
LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses., PMID:31985401
Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder., PMID:31875546
Features of non-activation dendritic state and immune deficiency in blastic plasmacytoid dendritic cell neoplasm (BPDCN)., PMID:31811114
Genomic Basis of Convergent Island Phenotypes in Boa Constrictors., PMID:31642474
BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis., PMID:31417183
PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation., PMID:29915291
Expression and clinical relations of protein tyrosine phosphatase receptor type S in esophageal squamous cell carcinoma., PMID:29745967
PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis., PMID:28614626
The Tetraspanin-Associated Uroplakins Family (UPK2/3) Is Evolutionarily Related to PTPRQ, a Phosphotyrosine Phosphatase Receptor., PMID:28099513
Unbiased identification of substrates of protein tyrosine phosphatase ptp-3 in C. elegans., PMID:27067626
For research use only. Not for human or drug use.
