Catalog No.
YHG42801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu6-Trp249
Predicted molecular weight
29.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13162
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Peroxiredoxin-4, Peroxiredoxin IV, Antioxidant enzyme AOE372, PRDX4, AOE37-2, Thioredoxin peroxidase AO372, Thioredoxin-dependent peroxiredoxin 4, Prx-IV, Thioredoxin-dependent peroxide reductase A0372
Identification and Validation of Feature Genes Related to Mitochondrial Dysfunction and Oxidative Stress in Ulcerative Colitis., PMID:40331161
PRDX-4: a novel biomarker similar to KL-6 for predicting the occurrence and progression of systemic sclerosis-ILD., PMID:40169424
Research progress on the role and molecular mechanism of PRDX4 in malignant tumors., PMID:40157831
Chemical Probe-Enabled Lipid Droplet Proteomics., PMID:40069114
Identification of Mitochondrial-related Characteristic Biomarkers in Osteosarcoma using Bioinformatics and Machine Learning., PMID:40012292
Characterisation of the prdx4 gene in Squalius cephalus and its role in freshwater environments with varying impact of perfluoroalkyl substances (PFAS)., PMID:39889648
The immunohistochemical combination of low SGLT2 expression and high PRDX4 expression independently predicts shortened survival in patients undergoing surgical resection for hepatoblastoma., PMID:39773476
PRDX4 mitigates diabetic retinopathy by inhibiting reactive gliosis, apoptosis, ER stress, oxidative stress, and mitochondrial dysfunction in Müller cells., PMID:39706273
A comprehensive review of peroxiredoxin 4, a redox protein evolved in oxidative protein folding coupled with hydrogen peroxide detoxification., PMID:39643136
H2S-Prdx4 axis mitigates Golgi stress to bolster tumor-reactive T cell immunotherapeutic response., PMID:39546607
Screening of pathologically significant diagnostic biomarkers in tears of thyroid eye disease based on bioinformatic analysis and machine learning., PMID:39544368
Serum peroxiredoxin-4, a biomarker of oxidative stress, associates with new-onset chronic kidney disease: A population-based cohort study., PMID:39490314
Lycium barbarum berry extract improves female fertility against aging-related oxidative stress in the ovary., PMID:39224078
Endoplasmic Reticulum Oxidative Stress Promotes Glutathione-Dependent Oxidation of Collagen-1A1 and Promotes Lung Fibroblast Activation., PMID:39042020
Peroxiredoxin 4 deficiency induces accelerated ovarian aging through destroyed proteostasis in granulosa cells., PMID:38971505
Regulatory role of PDK1 via integrated gene analysis of mitochondria-immune response in periodontitis., PMID:38657876
Revealing Prdx4 as a potential diagnostic and therapeutic target for acute pancreatitis based on machine learning analysis., PMID:38641608
Effects of antioxidant vitamins (A, D, E) and trace elements (Cu, Mn, Se, Zn) administration on gene expression, metabolic, antioxidants and immunological profiles during transition period in dromedary camels., PMID:38481237
Endothelial peroxiredoxin-4 is indispensable for blood-brain barrier integrity and long-term functional recovery after ischemic stroke., PMID:38437534
Validation of the interaction between PRDX4 and TXNDC5 in gastric cancer and the significance of the PRDX4 gene in gastric cancer based on a data mining analysis., PMID:38410208
Transcriptomic Analysis Reveals Sixteen Potential Genes Associated with the Successful Differentiation of Antibody-Secreting Cells through the Utilization of Unfolded Protein Response Mechanisms in Robust Responders to the Influenza Vaccine., PMID:38400120
Plasma concentrations of thioredoxin, thioredoxin reductase and peroxiredoxin-4 can identify high risk patients and predict outcome in patients with acute coronary syndrome: A clinical observation., PMID:38382848
The Clinical Relevance of the Expression of SGLT2 in Lung Adenocarcinoma., PMID:38232717
Exploring the role of PRDX4 in the development of uterine corpus endometrial carcinoma., PMID:38177789
Comparative Efficacy of Rosuvastatin Monotherapy and Rosuvastatin/Ezetimibe Combination Therapy on Insulin Sensitivity and Vascular Inflammatory Response in Patients with Type 2 Diabetes Mellitus., PMID:38173371
TMT-based quantitative proteomics reveals the targets of andrographolide on LPS-induced liver injury., PMID:37817228
The combination of the low immunohistochemical expression of peroxiredoxin 4 and perilipin 2 predicts longer survival in pancreatic ductal adenocarcinoma with peroxiredoxin 4 possibly playing a main role., PMID:37787446
Single-Cell Transcriptional and Epigenetic Profiles of Male Breast Cancer Nominate Salient Cancer-Specific Enhancers., PMID:37685859
MRI-based breast cancer radiogenomics using RNA profiling: association with subtypes in a single-center prospective study., PMID:37391754
Altered expression of MZB1 in periodontitis: A possible link to disease pathogenesis., PMID:37332260
High-resolution structural-omics of human liver enzymes., PMID:37289586
Breast cancer cell secretome analysis to decipher miRNA regulating the tumor microenvironment and discover potential biomarkers., PMID:37128318
Proteome profiling of endogenous and potential S-nitrosylation in colorectal cancer., PMID:37124724
Target proteins profiling of irreversible kinase inhibitor pelitinib and discovery of degradation of PRDX4 by label free chemoproteomics., PMID:37084663
Identification of common pathway and hub genes in the degeneration of both annulus fibrosus and nucleus pulposus in intervertebral disc., PMID:36972403
NADPH oxidase 1 in chronic pancreatitis-activated pancreatic stellate cells facilitates the progression of pancreatic cancer., PMID:36777508
In silico analysis reveals PRDX4 as a prognostic and oncogenic marker in renal papillary cell carcinoma., PMID:36646187
Peroxiredoxin-4 and Dopamine D5 Receptor Interact to Reduce Oxidative Stress and Inflammation in the Kidney., PMID:36401517
The deubiquitinase OTUD1 regulates immunoglobulin production and proteasome inhibitor sensitivity in multiple myeloma., PMID:36357400
Peroxiredoxin 4 secreted by cumulus cells ameliorates the maturation of oocytes in vitro., PMID:36334439
Bioinformatics Analysis of Common Genetic and Molecular Traits and Association of Portal Hypertension with Pulmonary Hypertension., PMID:36312597
Global landscape of protein complexes in postprandial-state livers from diet-induced obese and lean mice., PMID:36099783
PUFA-Derived N-Acylethanolamide Probes Identify Peroxiredoxins and Small GTPases as Molecular Targets in LPS-Stimulated RAW264.7 Macrophages., PMID:35867905
Consequences of a peroxiredoxin 4 (Prdx4) deficiency on learning and memory in mice., PMID:35809345
2D-DIGE-MS Proteomics Approaches for Identification of Gelsolin and Peroxiredoxin 4 with Lymph Node Metastasis in Colorectal Cancer., PMID:35804959
Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1., PMID:35646542
Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE-/- Mouse Model., PMID:35456043
Peroxiredoxin 4 regulates tumor-cell-like characteristics of fibroblast-like synoviocytes in rheumatoid arthritis through PI3k/Akt signaling pathway., PMID:35263665
Peroxiredoxin 4, a new favorable regulator, can protect oocytes against oxidative stress damage during in vitro maturation., PMID:35228121
Typical 2-Cys Peroxiredoxins as a Defense Mechanism against Metal-Induced Oxidative Stress in the Solitary Ascidian Ciona robusta., PMID:35052596
For research use only. Not for human or drug use.
