Catalog No.
YHG36801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn286-Pro561
Predicted molecular weight
33.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13002
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EAA4, GluR6, Glutamate receptor 6, Excitatory amino acid receptor 4, Glutamate receptor ionotropic, kainate 2, GluK2, GLUR6, GRIK2, GluR-6
De novo transcriptomic analysis to identify candidate genes potentially related to host recognition during infective stage of Caligus fugu (Crustacea: Copepoda)., PMID:39914265
Pubertal- and Stress-Dependent Changes in Cellular Activation and Expression of Excitatory Amino Acid Receptor Subunits in the Paraventricular Nucleus of the Hypothalamus in Male and Female Rats., PMID:39467516
Interplay of miRNAs and molecular pathways in spaceflight-induced depression: Insights from a rat model using simulated complex space environment., PMID:39037540
Structural and molecular dynamics simulation studies of CBL-interacting protein kinase CIPK and its complexes related to plant salinity stress., PMID:38965105
GRIK phosphorylates and activates KIN10 which also promotes its degradation., PMID:38590740
Causal role of myeloid cells in Parkinson's disease: Mendelian randomization study., PMID:38538756
Differential Proteomic Analysis of Low-Dose Chronic Paralytic Shellfish Poisoning., PMID:38535448
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging., PMID:38173016
Epigenetic signature discriminates lymphatic metastasis in BRAF wild-type thyroid carcinoma: methylation role of GRIK2., PMID:37990886
DOMAIN OF UNKNOWN FUNCTION581-9 negatively regulates SnRK1 kinase activity., PMID:37936321
A Pathogenic Missense Mutation in Kainate Receptors Elevates Dendritic Excitability and Synaptic Integration through Dysregulation of SK Channels., PMID:37802657
The atypical 'hippocampal' glutamate receptor coupled to phospholipase D that controls stretch-sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2., PMID:37656490
GluK2 Is a Target for Gene Therapy in Drug-Resistant Temporal Lobe Epilepsy., PMID:37341588
Interstitial 6q deletion in a patient presenting with drug-resistant epilepsy and Prader-Willi like phenotype: An electroclinical description with literature review., PMID:37210930
HROP68: A rare case of medullary pancreatic cancer-characterization and chemosensitivity of the first patient-derived cell line., PMID:36761421
Bioinformatic analysis and experimental validation identified DNA methylation-Related biomarkers and immune-cell infiltration of atherosclerosis., PMID:36159969
Deficiency of transmembrane AMPA receptor regulatory protein γ-8 leads to attention-deficit hyperactivity disorder-like behavior in mice., PMID:36031768
A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway., PMID:35807406
Ultrarare Loss-of-Function Mutations in the Genes Encoding the Ionotropic Glutamate Receptors of Kainate Subtypes Associated with Schizophrenia Disrupt the Interaction with PSD95., PMID:35629206
Deleted genes associated with obesity in Mexican patients diagnosed with nonalcoholic fatty liver disease., PMID:35343586
Alternative Promoters of GRIK2 (GluR6) Gene in Human Carcinoma Cell Lines Are Regulated by Differential Methylation of CpG Dinucleotides., PMID:35328043
Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration., PMID:35241647
Identification and Prognostic Value Exploration of Cyclophosphamide (Cytoxan)-Centered Chemotherapy Response-Associated Genes in Breast Cancer., PMID:34704810
Autozygosity mapping in consanguineous Pakistani families identifies nine non-overlapping novel linkage intervals for autosomal recessive non-syndromic mental retardation (AR-NSMR); shows genetic heterogeneity for AR-NSMR., PMID:34580524
Detection of fusion gene transcripts in the blood samples of prostate cancer patients., PMID:34417538
Clustered mutations in the GRIK2 kainate receptor subunit gene underlie diverse neurodevelopmental disorders., PMID:34375587
Genome-wide DNA methylation and gene expression analyses in monozygotic twins identify potential biomarkers of depression., PMID:34341332
Genome-wide association study identified INSC gene associated with Trail Making Test Part A and Alzheimer's disease related cognitive phenotypes., PMID:34224794
Validation of the functions and prognostic values of synapse-associated proteins in lower-grade glioma., PMID:33969375
Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer's Disease., PMID:33904022
Class I HDAC Inhibitor Improves Synaptic Proteins and Repairs Cytoskeleton Through Regulating Synapse-Related Genes In vitro and In vivo., PMID:33542682
Genetic and non-genetic factors associated with the phenotype of exceptional longevity & normal cognition., PMID:33154391
Senescence of Normal Human Fibroblasts Relates to the Expression of Ionotropic Glutamate Receptor GluR6/Grik2., PMID:33099472
Truncated RUNX1 Generated by the Fusion of RUNX1 to Antisense GRIK2 via a Cryptic Chromosome Translocation Enhances Sensitivity to Granulocyte Colony-Stimulating Factor., PMID:32544910
A Novel Susceptibility Locus Near GRIK2 Associated With Erosive Esophagitis in a Korean Cohort., PMID:32132452
Transcriptome analysis of rat dorsal hippocampal CA1 after an early life seizure induced by kainic acid., PMID:32062370
Temporal Changes of Spinal Transcriptomic Profiles in Mice With Spinal Nerve Ligation., PMID:31920516
Whole-Transcriptome Analysis of Dermal Fibroblasts, Derived from Three Pairs of Monozygotic Twins, Discordant for Parkinson's Disease., PMID:31823283
Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans., PMID:31792237
The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging., PMID:31767166
Correlation between GRIK2 rs6922753, rs2227283 polymorphism and aggressive behaviors with Bipolar Mania in the Chinese Han population., PMID:31631587
Neto proteins regulate gating of the kainate-type glutamate receptor GluK2 through two binding sites., PMID:31628192
Genome-Wide Scan Identifies Selection Signatures in Chinese Wagyu Cattle Using a High-Density SNP Array., PMID:31151238
Interaction among GRIK2 gene on epilepsy susceptibility in Chinese children., PMID:30908586
Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction., PMID:30770891
Identification of recurrent fusion genes across multiple cancer types., PMID:30705370
Isoforms of Ionotropic Glutamate Receptor GRIK2 Induce Senescence of Carcinoma Cells., PMID:30587499
ADAR2-mediated Q/R editing of GluK2 regulates kainate receptor upscaling in response to suppression of synaptic activity., PMID:30559217
Trehalose 6-Phosphate Positively Regulates Fatty Acid Synthesis by Stabilizing WRINKLED1., PMID:30249634
Kainate Receptors Inhibit Glutamate Release Via Mobilization of Endocannabinoids in Striatal Direct Pathway Spiny Projection Neurons., PMID:29540547
For research use only. Not for human or drug use.
