Catalog No.
YHG36501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys150
Predicted molecular weight
19.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12988
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Heat shock 17 kDa protein, HSPL27, HSP 17, Protein 3, Heat shock protein beta-3, HSPB3, HSP27, HspB3
Identification of the immune infiltration and biomarkers in ulcerative colitis based on liquid-liquid phase separation-related genes., PMID:39915583
Genetic and Pharmacological Modulation of Cellular Proteostasis Leads to Partial Functional Rescue of Homocystinuria-Causing Cystathionine-Beta Synthase Variants., PMID:38051092
PINK1 and Parkin rescue motor defects and mitochondria dysfunction induced by a patient-derived HSPB3 mutant in Drosophila models., PMID:37804589
Dynamics and Composition of Small Heat Shock Protein Condensates and Aggregates., PMID:37146746
Clinical exome sequencing findings in 1589 patients., PMID:36964972
Evaluation of the Small Heat Shock Protein Family Members HSPB2 and HSPB3 in Bladder Cancer Prognosis and Progression., PMID:36768927
Identification of Potential Biomarkers and Immune Infiltration Characteristics in Ulcerative Colitis by Combining Results from Two Machine Learning Algorithms., PMID:35959356
Human HspB1, HspB3, HspB5 and HspB8: Shaping these disease factors during vertebrate evolution., PMID:35678958
Genetic and Clinical Studies of Peripheral Neuropathies with Three Small Heat Shock Protein Gene Variants in Korea., PMID:35328016
Association between chronic periodontitis and the risk of Alzheimer's disease: combination of text mining and GEO dataset., PMID:34556089
The Importance of Multiple Gene Analysis for Diagnosis and Differential Diagnosis in Charcot Marie Tooth Disease., PMID:34169998
Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor., PMID:33958580
Identification of Biomarkers Related to CD8+ T Cell Infiltration With Gene Co-expression Network in Lung Squamous Cell Carcinoma., PMID:33816462
Small heat shock proteins in neurodegenerative diseases., PMID:32323160
Neuromuscular Diseases Due to Chaperone Mutations: A Review and Some New Results., PMID:32093037
Heat shock protein beta 3 (HSPB3) is an unfavorable molecular biomarker in colorectal adenocarcinoma., PMID:31709619
Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3., PMID:29969581
Small heat shock protein B3 (HSPB3) mutation in an axonal Charcot-Marie-Tooth disease family., PMID:29341343
Direct biological effects of fractional ultrapulsed CO2 laser irradiation on keratinocytes and fibroblasts in human organotypic full-thickness 3D skin models., PMID:29218493
Aberrant Compartment Formation by HSPB2 Mislocalizes Lamin A and Compromises Nuclear Integrity and Function., PMID:28854361
Upregulation and phosphorylation of HspB1/Hsp25 and HspB5/αB-crystallin after transient middle cerebral artery occlusion in rats., PMID:28425051
A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies., PMID:28202467
An interaction study in mammalian cells demonstrates weak binding of HSPB2 to BAG3, which is regulated by HSPB3 and abrogated by HSPB8., PMID:28181153
Axonal Neuropathies due to Mutations in Small Heat Shock Proteins: Clinical, Genetic, and Functional Insights into Novel Mutations., PMID:28144995
Chaperonopathies: Spotlight on Hereditary Motor Neuropathies., PMID:28018906
The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins., PMID:27909051
HSPB3 protein is expressed in motoneurons and induces their survival after lesion-induced degeneration., PMID:27567740
Small Heat Shock Proteins and Distal Hereditary Neuropathies., PMID:26878578
Aberrant Autophagic Response in The Muscle of A Knock-in Mouse Model of Spinal and Bulbar Muscular Atrophy., PMID:26490709
Mitochondrial dynamics and inherited peripheral nerve diseases., PMID:25847151
[Coexpression of genes located in the 111.35-116.16 Mb of chromosome 13 in mice with different predisposition to catalepsy]., PMID:25842858
Upregulation of heat shock proteins (HSPA12A, HSP90B1, HSPA4, HSPA5 and HSPA6) in tumour tissues is associated with poor outcomes from HBV-related early-stage hepatocellular carcinoma., PMID:25798051
Gene expression of Hsps in normal and abnormal embryonic development of mouse hindlimbs., PMID:25352652
Expression and induction of small heat shock proteins in rat heart under chronic hyperglycemic conditions., PMID:24950024
Neuropathy- and myopathy-associated mutations in human small heat shock proteins: Characteristics and evolutionary history of the mutation sites., PMID:24607769
An exploration of heat tolerance in mice utilizing mRNA and microRNA expression analysis., PMID:23967293
Mutations of small heat shock proteins and human congenital diseases., PMID:23379525
Structural aspects and chaperone activity of human HspB3: role of the "C-terminal extension"., PMID:22610661
Inhibition of α-synuclein aggregation by small heat shock proteins., PMID:21905118
Molecular genetics and mechanisms of disease in distal hereditary motor neuropathies: insights directing future genetic studies., PMID:21902652
Small heat shock proteins induce a cerebral inflammatory reaction., PMID:21849559
Map3k1, Il6st, Gzmk, and Hspb3 gene coexpression network in the mechanism of freezing reaction in mice., PMID:21162133
Differential expression and induction of small heat shock proteins in rat brain and cultured hippocampal neurons., PMID:21162124
The genetics of spinal muscular atrophies., PMID:20733483
Leptin administration downregulates the increased expression levels of genes related to oxidative stress and inflammation in the skeletal muscle of ob/ob mice., PMID:20671928
High-resolution two-dimensional gel electrophoresis analysis of atrial tissue proteome reveals down-regulation of fibulin-1 in atrial fibrillation., PMID:20451270
Mutant small heat shock protein B3 causes motor neuropathy: utility of a candidate gene approach., PMID:20142617
Gene expression of sHsps, Hsp40 and Hsp60 families in normal and abnormal embryonic development of mouse forelimbs., PMID:20117194
The small heat-shock proteins HSPB2 and HSPB3 form well-defined heterooligomers in a unique 3 to 1 subunit ratio., PMID:19715703
Interactions of HSP22 (HSPB8) with HSP20, alphaB-crystallin, and HSPB3., PMID:16225851
For research use only. Not for human or drug use.
