Catalog No.
EHG33801
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Lys68-Ser225
Predicted molecular weight
45.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12918
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CLEC5B, KLRB1, CD161, HNKR-P1a, C-type lectin domain family 5 member B, NKRP1A, Natural killer cell surface protein P1A, Killer cell lectin-like receptor subfamily B member 1, NKR-P1A
Adaptive NKG2C+ NK cells in cytomegalovirus seropositive individuals predominantly lack NKR-P1A receptor expression., PMID:40426298
[Protective аction of ginseng root extract on myofibril apoptosis and immune response in rats after exhausting physical exercise. Part II. Effect of ginseng root extract on immunity and regulation of energy metabolism]., PMID:40418135
Systems analysis unravels a common rural-urban gradient in immunological profile, function, and metabolic dependencies., PMID:40305616
Liver transplant-facilitated CD161+Vα7.2+ MAIT cell recovery demonstrates clinical benefits in hepatic failure patients., PMID:40301342
Correlation of the Expression Profile of Peripheral Leukocyte and Liver Tissue Immune Markers With Serum Liver Injury Indices in Children With Biliary Atresia., PMID:40270513
Combined CLEC2d Expression and CD58 Loss Mitigate Rejection of Allogeneic T Cells., PMID:40171839
High tumor CD161 expression predicts a survival advantage and marks a Th1-skewed microenvironment., PMID:40165951
CD161, a promising prognostic biomarker in hepatocellular carcinoma, correlates with immune infiltration., PMID:40115278
Classification of NK-large granular lymphocytic leukemia by CD56 expression., PMID:40063609
Anti-SSA/SSB antibody double-negative Sjögren's disease patients: a comprehensive clinical study and immune profile., PMID:39969675
Natural Killer Cells in Graves' Disease: Increased Frequency but Impaired Degranulation Ability Compared to Healthy Controls., PMID:39940745
A Phenotypically Distinct Human Th2 Cell Subpopulation Is Associated With Development of Allergic Disorders in Infancy., PMID:39899007
OMIP-110: A 37-Color Spectral Flow Cytometric Panel to Assess Transcription Factors and Chemokine Receptors in Human Intestinal Lymphoid Cells., PMID:39838760
Proteomic analysis reveals dysregulation of peripheral blood neutrophils in patients with Multiple Sclerosis., PMID:39817476
Intrahepatic CD161hiCD8+T Cell Recruitment Has a Pathogenetic Potential in Chronic HBV Infection., PMID:39799583
Mouse CD8+ T cell subsets differentially generate IL-17-expressing cells in the colon epithelium and lamina propria., PMID:39745881
CD3+CD4-CD8- Double-Negative Lymphocytes Are Increased in the Aqueous Humor of Patients with Retinitis Pigmentosa: Their Possible Role in Mediating Inflammation., PMID:39684872
Klrb1 Loss Promotes Chronic Hepatic Inflammation and Metabolic Dysregulation., PMID:39596644
Expression of senescence-related CD161 promotes extranodal NK/T cell lymphoma by affecting T cell phenotype and cell cycle., PMID:39580409
CCR5 mediates rheumatoid arthritis progression by promoting the activation and proliferation of non-classical Th1 cells., PMID:39558608
Targeting LLT1 as a potential immunotherapy option for cancer patients non-responsive to existing checkpoint therapies in multiple solid tumors., PMID:39511540
The Expression pattern of NK cells in systemic lupus erythematosus patients with different disease activities., PMID:39427243
A shotgun proteomic dataset of human mucosal-associated invariant T cells., PMID:39224509
Immunological insights: assessing immune parameters in medical professionals exposed to SARS-CoV-2., PMID:39187767
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID-19., PMID:39094122
Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis., PMID:39024572
CD161+CD127+CD8+ T cell subsets can predict the efficacy of anti-PD-1 immunotherapy in non-small cell lung cancer with diabetes mellitus., PMID:38952673
Deciphering the role of KLRB1: a novel prognostic indicator in hepatocellular carcinoma., PMID:38914941
Immunological characteristics of CD103+CD161+ T lymphocytes on chronic rhinosinusitis with nasal polyps., PMID:38897020
A Comprehensive Investigation of Stimulatory Agents on MAIT and Vα7.2+/CD161- T Cell Response and Effects of Immunomodulatory Drugs., PMID:38892082
Single-cell analysis reveals cellular and molecular factors counteracting HPV-positive oropharyngeal cancer immunotherapy outcomes., PMID:38857913
Unconventional T Cells Influence Clinical Outcome After Allogeneic Hematopoietic Cell Transplantation., PMID:38822857
A unique human cord blood CD8+CD45RA+CD27+CD161+ T-cell subset identified by flow cytometric data analysis using Seurat., PMID:38798051
Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD., PMID:38782996
Modulation of the Immunological Milieu in Acute Aneurysmal Subarachnoid Hemorrhage: The Potential Role of Monocytes Through CXCL10 Secretion., PMID:38780865
Venetoclax acts as an immunometabolic modulator to potentiate adoptive NK cell immunotherapy against leukemia., PMID:38776913
Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies., PMID:38714671
Impact of Lithium on the Immune System: An Investigation of T-Cell Subpopulations and Cytokine Responses in Rats., PMID:38700635
High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL-17 against M. tuberculosis antigen., PMID:38698866
KLRB1 defines an activated phenotype of CD4+ T cells and shows significant upregulation in patients with primary Sjögren's syndrome., PMID:38636371
A comprehensive analysis of the KLRB1 expression and its clinical implication in testicular germ cell tumors: A review., PMID:38608099
Single-cell sequencing analysis and multiple machine-learning models revealed the cellular crosstalk of dendritic cells and identified FABP5 and KLRB1 as novel biomarkers for psoriasis., PMID:38596682
The proportion of CD161 on CD56+ NK cells in peripheral circulation associates with clinical features and disease activity of primary Sjögren's syndrome., PMID:38577997
Investigating Vα7.2+/CD161- T Cell and MAIT Cell Profiles Using Flow Cytometry in Healthy Subjects and Subjects with Atopic Dermatitis., PMID:38542456
Immune checkpoint CD161/LLT1-associated immunological landscape and diagnostic value in oral squamous cell carcinoma., PMID:38502058
Combined IL6 and CCR2 blockade potentiates antitumor activity of NK cells in HPV-negative head and neck cancer., PMID:38468260
Th17/1 and ex-Th17 cells are detected in patients with polyarticular juvenile arthritis and increase following treatment., PMID:38431635
Radiofrequency ablation plays double role in immunosuppression and activation of PBMCs in recurrent hepatocellular carcinoma., PMID:38348038
Study of pathogenic T-helper cell subsets in Asian Indian patients with Takayasu arteritis., PMID:38326692
HELIOS-expressing human CD8 T cells exhibit limited effector functions., PMID:38187391
For research use only. Not for human or drug use.
