Catalog No.
YHG33401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp45-Arg322
Predicted molecular weight
33.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12907
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C5orf8, VIP36, Vesicular integral-membrane protein 36, Vesicular integral-membrane protein VIP36, LMAN2, Glycoprotein GP36b, Lectin mannose-binding 2
Identification of protein biomarker candidates associated with organ-specific immune-related toxicity and response to management by plasma proteomics., PMID:40510441
Host and bacterial urine proteomics might predict treatment outcomes for immunotherapy in advanced non-small cell lung cancer patients., PMID:40297587
COVID-19 related epigenetic changes and atopic dermatitis: An exploratory analysis., PMID:39867872
LMAN2 interacts with HEATR3 to expedite HER2-positive breast cancer advancement and inflammation and Akt/ERK/NF-κB signaling., PMID:39772898
Identification of potential pathogenic genes for urolithiasis through multi-omics Mendelian randomization analysis., PMID:39680155
Competitive modulation of KV1.2 gating by LMAN2 and Slc7a5., PMID:39659243
LMAN2 Promotes Breast Cancer Tumorigenesis and Drug Resistance by Interacting With MAPK9 via Activation of the MAPK Pathway., PMID:39618331
Exploring susceptibility and therapeutic targets for kidney stones through proteome-wide Mendelian randomization., PMID:39530187
Regulation of Kv1.2 Redox-Sensitive Gating by the Transmembrane Lectin LMAN2., PMID:39264045
Plasma proteome analysis implicates novel proteins as potential therapeutic targets for chronic kidney disease: A proteome-wide association study., PMID:38828357
Alterations in the Circulating Proteome Associated with Albuminuria., PMID:36890639
Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood., PMID:36759259
Identification of salivary autoantibodies as biomarkers of oral cancer with immunoglobulin A enrichment combined with affinity mass spectrometry., PMID:36625099
Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients., PMID:35766008
Comprehensive Analysis of the Expression and Prognostic Value of LMAN2 in HER2+ Breast Cancer., PMID:35707004
Valosin Containing Protein as a Specific Biomarker for Predicting the Development of Acute Coronary Syndrome and Its Complication., PMID:35369356
MXD3 as an onco-immunological biomarker encompassing the tumor microenvironment, disease staging, prognoses, and therapeutic responses in multiple cancer types., PMID:34584637
Endoplasmic reticulum stress-related secretory proteins as biomarkers of early myocardial ischemia-induced sudden cardiac deaths., PMID:34580752
Proteins Associated with Risk of Kidney Function Decline in the General Population., PMID:34465608
Mapping of the amniotic fluid proteome of fetuses with congenital anomalies of the kidney and urinary tract identifies plastin 3 as a protein involved in glomerular integrity., PMID:33987838
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor., PMID:32515674
One-Step Enrichment of Intact Glycopeptides From Glycoengineered Chinese Hamster Ovary Cells., PMID:32363175
Recombinant Expression and Purification of Animal Intracellular L-Type Lectins., PMID:32306311
Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles., PMID:31882861
White matter DNA methylation profiling reveals deregulation of HIP1, LMAN2, MOBP, and other loci in multiple system atrophy., PMID:31535203
Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals., PMID:30993211
Overexpression of quality control proteins reduces prion conversion in prion-infected cells., PMID:30154245
Combining multi-dimensional data to identify a key signature (gene and miRNA) of cisplatin-resistant gastric cancer., PMID:29693274
Comparative Proteomics Analysis of Urine Reveals Down-Regulation of Acute Phase Response Signaling and LXR/RXR Activation Pathways in Prostate Cancer., PMID:29286311
Adaptor protein CD2AP and L-type lectin LMAN2 regulate exosome cargo protein trafficking through the Golgi complex., PMID:28986432
Diet-induced reconstruction of mucosal microbiota associated with alterations of epithelium lectin expression and regulation in the maintenance of rumen homeostasis., PMID:28638072
Adaptor Protein CD2AP and L-type Lectin LMAN2 Regulate Exosome Cargo Protein Trafficking through the Golgi Complex., PMID:27765817
Nano LC-MS Based Proteomic Analysis as a Predicting Approach to Study Cellular Responses of Carbon Nanotubes., PMID:27455640
Structural basis for disparate sugar-binding specificities in the homologous cargo receptors ERGIC-53 and VIP36., PMID:24498414
Site-specific N-linked glycosylation of receptor guanylyl cyclase C regulates ligand binding, ligand-mediated activation and interaction with vesicular integral membrane protein 36, VIP36., PMID:23269669
SILAC-based quantitative proteomic analysis of gastric cancer secretome., PMID:23161554
Subcellular localization of ERGIC-53 under endoplasmic reticulum stress condition., PMID:22821029
VIP36 protein is a target of ectodomain shedding and regulates phagocytosis in macrophage Raw 264.7 cells., PMID:22016386
Role of the lectin VIP36 in post-ER quality control of human alpha1-antitrypsin., PMID:20477988
Molecular basis of sugar recognition by the human L-type lectins ERGIC-53, VIPL, and VIP36., PMID:18025080
VIPL has sugar-binding activity specific for high-mannose-type N-glycans, and glucosylation of the alpha1,2 mannotriosyl branch blocks its binding., PMID:17621594
Stable interaction of the cargo receptor VIP36 with molecular chaperone BiP., PMID:17586539
Detection of weak sugar binding activity of VIP36 using VIP36-streptavidin complex and membrane-based sugar chains., PMID:17169971
Sugar-binding properties of VIP36, an intracellular animal lectin operating as a cargo receptor., PMID:16129679
VIPL, a VIP36-like membrane protein with a putative function in the export of glycoproteins from the endoplasmic reticulum., PMID:12878160
The cargo receptor ERGIC-53 is a target of the unfolded protein response., PMID:12727195
Profile-based data base scanning for animal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein., PMID:12609988
Quantitative ER <--> Golgi transport kinetics and protein separation upon Golgi exit revealed by vesicular integral membrane protein 36 dynamics in live cells., PMID:11359937
VIP36 localisation to the early secretory pathway., PMID:10444376
For research use only. Not for human or drug use.
